1 results match your criteria: "Barcelona hUniversitat de Vic (UVic-UCC)[Affiliation]"
Highly pathogenic adapted HIV-1 strains limit host immunity and dictate rapid disease progression.
AIDS
June 2014
aAIDS Research Institute -IrsiCaixa-iInstitut d'Investigació en Ciències de la Salut Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain bInstitute of Microbiology, University Hospital Center and University of Lausanne, Lausanne cUniversity Clinic of Infectious Diseases, University Hospital Bern and University of Bern, Bern, Switzerland dUniversidad Complutense de Madrid, Madrid, Spain eMonogram Biosciences, South San Francisco, California, USA fCentre d'Estudis Epidemiològics sobre les Infeccions de Transmissió Sexual i Sida de Catalunya (CEEISCAT), Badalona gBanc de Sang i Teixits, Barcelona hUniversitat de Vic (UVic-UCC), Vic iInstitució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain. *Judith Dalmau and Margalida Rotger contributed equally to this article. †Amalio Talenti, Javier Martinez-Picado and Julia G. Prado contributed equally to the work.
Objective: The study of HIV-1 rapid progressors has been limited to specific case reports. Nevertheless, identification and characterization of the viral and host factors involved in rapid progression are crucial when attempting to uncover the correlates of rapid disease outcome.
Design: We carried out comparative functional analyses in rapid progressors (n = 46) and standard progressors (n = 46) early after HIV-1 seroconversion (≤1 year).