345 results match your criteria: "Bangur Institute of Neurosciences[Affiliation]"

 Vascular dementia is the second leading cause of dementia worldwide. Its heterogenous presentation along with potential for reversibility at earlier stages makes it unique among all dementias.  We aimed to study the cognitive dysfunction in large-vessel vascular dementia.

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Dystonic storm (also called status dystonicus) is a neurological emergency characterized by sustained/intermittent involuntary generalized muscle contractions resulting in repetitive painful twisting movements and abnormal postures. It is commonly documented in patients with diagnosed primary dystonic syndromes or secondary dystonic states (i.e.

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Rare neurological and neuropsychiatric manifestations of scrub typhus: a case series of 10 cases.

Neurologia (Engl Ed)

December 2024

Department of Neurology, University Hospital "12 de Octubre", Madrid, Spain; Centro de Investigación Biomédica en Red Sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain; Department of Medicine, Complutense University, Madrid, Spain. Electronic address:

Introduction: Scrub typhus is a potentially life-threatening but curable disease that can produce multi-organ failure. Neurological manifestations in scrub typhus have gained attention recently, where the entire neural axis except the myoneural junction can be involved. Although the pathogenesis of neurological involvement has not been established, immune-mediated mechanisms are suspected.

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Snakebite envenomation-induced posterior reversible encephalopathy syndrome presenting with Bálint syndrome.

Neurologia (Engl Ed)

June 2023

Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain; Centro de Investigación Biomédica en Red Sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain; Department of Medicine, Complutense University, Madrid, Spain. Electronic address:

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Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune astrocytopathy against foot processes of aquaporin-4 (AQP4) water channels. Patients with NMOSD tend to have other coexisting autoimmune/connective tissue diseases. However, AQP-4-antibody-positive NMOSD coexisting with ankylosing spondylitis (AS) is rare.

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Multiple sclerosis and Moyamoya angiopathy: Mimic and misdiagnosis.

Mult Scler Relat Disord

October 2022

Department of Neurology, Institute of Post Graduate Medical Education & Research, Bangur Institute of Neurosciences, Kolkata, India. Electronic address:

Article Synopsis
  • - Moyamoya Angiopathy (MMA) is often overlooked when diagnosing Multiple Sclerosis (MS), leading to misdiagnoses, as highlighted in this first prospective study.
  • - Out of 160 confirmed MMA cases, 5 (3.13%) were initially misdiagnosed as MS, predominantly affecting females (80%), with most presenting symptoms like hemiparesis and having identifiable triggers.
  • - Key radiological features aiding differentiation included the presence of "Ivy" sign and abnormal flow voids, with careful examination of white matter lesions being crucial to accurately distinguish MMA from MS.
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Parkinson's disease (PD) is a genetically heterogeneous neurodegenerative disease with poorly defined environmental influences. Genomic studies of PD patients have identified disease-relevant monogenic genes, rare variants of significance, and polygenic risk-associated variants. In this study, whole genome sequencing data from 90 young onset Parkinson's disease (YOPD) individuals are analyzed for both monogenic and polygenic risk.

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Objective: Bengali, the 6th most spoken language globally with 268 million speakers, demands a culturally appropriate tool for screening any cognitive compromise in this population. Addenbrooke Cognitive Examination-III (ACE-III) is a standardized tool used for screening and/or diagnostic purpose worldwide. The aim of the present study was to adapt and validate ACE-III into Bengali language.

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Background: Diabetic striatopathy (DS), coined as a generic term, has been defined as a hyperglycemic condition associated with either one of the two following conditions: chorea/ballism or striatal hyperdensity on computed tomography or striatal hyperintensity on T1-weighted magnetic resonance imaging. This review highlights those "gray areas," which need further exploration to understand better hyperglycemia-induced striatal changes and diverse movement disorder phenotypes associated with these changes.

Results And Discussion: We searched in PubMed and Google Scholar the terms "diabetes mellitus," "movement disorders," "diabetic striatopathy," "chorea," "hemichorea," "ballism," "hemichorea-hemiballism," and "neuroradiology" in various combinations (time range from 1980 to March 2022).

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Post-Varicella Neurological Complications: A Preliminary Observation from a Tertiary Care Centre of Eastern India.

Ann Indian Acad Neurol

February 2022

Department of Neuromedicine, Bangur Institute of Neurosciences, IPGMER and SSKM Hospital, Kolkata, West Bengal, India.

Article Synopsis
  • This study analyzed 17 cases of neurological complications that developed after acute varicella (chickenpox) infection, looking into clinical symptoms, imaging findings, and patient outcomes.
  • Patients, ranging from childhood to middle age, exhibited various neurological issues, with peripheral nervous system disorders like Guillain-Barré syndrome being the most common.
  • While serious complications like encephalitis were less frequent compared to some studies, most patients responded well to treatment, particularly for demyelinating conditions, though outcomes were less favorable for those with ataxia.
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Background: To combat the COVID-19 pandemic, several countries imposed strict lockdown to ensure social distancing to limit the spread of the virus. This caused difficulties in the management and care of patients with various chronic disorders including dementia.

Objectives: The objective of the study was to explore the health condition of patients with dementia and assess their caregivers' burden during the lockdown.

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Rapidly progressive dementia with generalized myoclonus in an adult: Do not forget subacute sclerosing panencephalitis.

Neurologia (Engl Ed)

June 2022

Department of Neurology, University Hospital "12 de Octubre", Madrid, Spain; Department of Neurology, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain; Department of Medicine, Complutense University, Madrid, Spain. Electronic address:

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Prognostic indicators and outcomes of hospitalised COVID-19 patients with neurological disease: An individual patient data meta-analysis.

PLoS One

June 2022

National Institute for Health Research Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.

Background: Neurological COVID-19 disease has been reported widely, but published studies often lack information on neurological outcomes and prognostic risk factors. We aimed to describe the spectrum of neurological disease in hospitalised COVID-19 patients; characterise clinical outcomes; and investigate factors associated with a poor outcome.

Methods: We conducted an individual patient data (IPD) meta-analysis of hospitalised patients with neurological COVID-19 disease, using standard case definitions.

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Background: Multiple sclerosis (MS), a subset of chronic primary inflammatory demyelinating disorders of the central nervous system, is closely associated with various movement disorders. These disorders may be due to MS pathophysiology or be coincidental. This review describes the full spectrum of movement disorders in MS with their possible mechanistic pathways and therapeutic modalities.

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Introduction: Neurological disorders in pregnancy may be observed in patients with a pre-existing neurological disorder; patients developing a primary neurological disorder during the course of pregnancy or puerperium; and in patients with primary medical disorders presenting with neurological manifestations.

Objectives: The objectives of the study were to find out the magnitude of neurological disorders in pregnancy in a tertiary care hospital along with assessment of proportion of women with particular disorders among total number of neurological disorders during the course of pregnancy or puerperium (6 weeks after child birth) and also to elicit the effect of neurological disorders on pregnancy outcome, if any.

Methods: A prospective observational longitudinal study was carried out in a tertiary care centre of Eastern India from July 2018 to June 2020 including all pregnant women attending the department of Obstetrics and Gynaecology.

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Background: Genetic factors, including causal gene and modifier genes, contribute significantly in PD pathogenesis in an ethnicity-dependent manner. Dopamine Receptor 4 (DRD4), involved in dopamine metabolism is one such modifier locus for PD.

Objective: To identify the potential association of DRD4 polymorphic variants with PD among Eastern Indians.

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Epigenetics, hypothalamic-pituitary axes, environmental and metabolic influences, and transgenerational plasticity govern social behavior. Cognitive research considers the brain's default mode network (DMN) as a central hub that integrates various cognitive and social processing domains responsible for emotion perception, empathy, theory of mind, and morality. Hence, DMN is regarded as the "social brain.

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Hemifacial spasm followed by predominantly unilateral upper limb monochorea unmasking type-2 diabetes mellitus.

Neurologia (Engl Ed)

April 2022

Department of Neurology, University Hospital "12 de Octubre", Madrid, Spain; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain; Department of Medicine, Complutense University, Madrid, Spain. Electronic address:

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The alien limb is a phenomenon characterized by a cluster of clinical features wherein the limb behaves autonomously and as separated from a person's identity. We herein report a 36-year-old Indian female with multiple comorbidities who presented with recurrent episodes of limb-shaking transient ischemic attacks for 1 year, followed by left-sided hemiplegia. During recovering, the patient noticed a feeling that as if her left hand did not belong to herself and acted autonomously (alien limb phenomenon) along with visuospatial deficits.

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Article Synopsis
  • A study explored acute onset movement disorders in 59 patients with diabetes mellitus (DM) in West Bengal, finding that most had choreic or ballistic movements, with ballism being the most common disorder.
  • The analysis revealed that 76.3% of patients experienced nonketotic hyperglycemia, and 55.9% showed no MRI abnormalities while some exhibited striatal hyperintensity.
  • The research emphasizes the need for blood glucose checks in patients with sudden movement disorders, even if they have normal past glycemic levels, as most (76.3%) recovered fully.
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"Asymptomatic" Moyamoya Angiopathy: Is it Truly Asymptomatic?

J Stroke Cerebrovasc Dis

June 2022

Department of Neurology, Institute of Post Graduate Medical Education & Research, Bangur Institute of Neurosciences, Kolkata, India. Electronic address:

Introduction: An ambiguous definition of "asymptomatic" Moyamoya Angiopathy(aMMA) of absence of ischemic/hemorrhagic episodes in MMA patients, has led to its variable adaptation in the limited past-studies.

Objective: To observe the clinic-radiological characteristics and prospective follow-up of apparently "asymptomatic" MMA, and to determine if it is truly asymptomatic or not.

Materials And Methods: An observation, cohort study of 122 angiographically proven MMA over 6 years was undertaken from a single, tertiary-care-center to observe the clinico-radiological characteristics, prospective follow-up of apparently aMMA.

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