Effectiveness of ginger for prevention of nausea and vomiting after gynecological laparoscopy.

Objective: To study the effectiveness of ginger for prevention of nausea and vomiting after gynecological laparoscopy.

Material And Method: From July 2005 to October 2005, 60 inpatients who underwent laparoscopic operations for non-cancer gynecologic conditions at Bangkok Metropolitan Administration Medical College or Vajira Hospital were randomized into Group A (n = 30) or Group B (n = 30). Group A received 3 capsules of ginger (1 capsule contained 0.

Primary umbilical endometriosis.

A 45-year old nulliparous woman presented with umbilical pigmented lesion with cyclical bleeding. The lesion was excised and pathological diagnosis was umbilical endometriosis. The authors reviewed the current literature and discussed the different diagnosis and management of umbilical endometriosis.

Lymph node size in uterine cancer: A revisit.

To study whether lymph node size is a good predictor of lymph node metastasis in uterine cancer, we reviewed the pathologic sections of pelvic and para-aortic lymph node removed from uterine cancer patients who underwent surgical staging in our institution from January 1994 to December 2004. The long axis of each individual node was measured. Out of 4280 total nodes obtained (178 cases), 86 nodes (28 cases) were positive for metastatic cancer (2.

Tumor persistence in high grade squamous intraepithelial lesion patients with positive surgical margin post loop electrosurgical excision procedure.

Objective: To determine the rates of persistent and recurrent tumors in patients with High Grade Squamous Intraepithelial Lesion (HSIL) who had positive surgical margin from Loop Electrosurgical Excision Procedure (LEEP).

Material And Method: Clinical and pathological data of all women who underwent LEEP procedures and revealed HSIL lesions with positive surgical margin between July 1997 and December 2004 were recorded.

Results: Histologic diagnoses of HSIL with positive surgical margin were found in 95 cases during the study period.

Prenatal vitamin K1 administration in epileptic women to prevent neonatal hemorrhage: is it effective?

Objective: To summarize current knowledge on whether prenatal prophylactic vitamin K1 administration to epileptic women receiving enzyme-inducing antiepileptic drugs (AEDs) to prevent neonatal hemorrhage is effective.

Study Design: A computerized MEDLINE search was conducted using the terms antiepileptic drug, hemorrhagic disease of the newborn, pregnancy and vitamin K since 1966 to July 2004, limited only to human studies. English-language publications were selected based on their relevance to the clinical effectiveness of administration of oral vitamin K to epileptic women exposed to enzyme-inducing AEDs for prevention of hemorrhagic disease of the newborn (HDN).

Survival rate of recurrent cervical cancer patients.

Objectives: To determine the survival rate of recurrent cervical cancer patients and factors influencing survival.

Material And Method: The subjects were identified from the Gynecologic Oncology Unit tumor registry record The pathological, clinical data including the follow-up information of recurrent cervical cancer patients who were treated in the Gynecologic Oncology Unit, Bangkok Metropolitan Administration Medical College and Vajira Hospital between 1992 and 2003 were retrospective reviewed.

Results: During the study period, 144 recurrent cervical cancer patients were identified.

Efficacy of platinum plus cyclophosphamide in patients with epithelial ovarian cancer.

Objectives: To determine the response rate (RR), 5-year progression-free survival (PFS), and the 5-year survival rate (SVR) of epithelial ovarian cancer patients who received platinum plus cyclophosphamide as adjuvant postoperative chemotherapy.

Material And Method: Epithelial ovarian cancer patients who underwent tumor debulking surgery and received platinum plus cyclophosphamide as adjuvant chemotherapy at Vajira Hospital from January 1995 to December 2003 were identified. All clinical and pathological data were reviewed

Results: Among 114 patients included in the present study, 101 patients were evaluable for response.

The growing teratoma syndrome: a case report and a review of the literature.

We present the case of a 5-year-old girl with ovarian immature teratoma, which recurred a few months after an incomplete surgical staging. The recurrent masses, located in the upper abdomen and lower pelvis, were accompanied by rise in levels of serum alpha-fetoprotein. The patient and her parents refused surgical resection of these recurrent masses; therefore, chemotherapy was promptly given.

Association between Bcl-2 expression and tumor recurrence in cervical cancer: a matched case-control study.

Objectives: To evaluate the association between bcl-2 expression, some pathological factors (lymph-vascular space invasion (LVSI), tumor grade, depth of stromal invasion), and tumor recurrence in cervical cancer.

Methods: A matched case-control study was performed in cervical cancer patients who underwent radical hysterectomy and were found to have negative lymph node between January 1992 and June 1998 in Bangkok Metropolitan Administration Medical College and Vajira Hospital and Maharaj Nakorn Chiangmai Hospital, Thailand. Cases were 32 patients who had tumor recurrence within 5 years after surgery.

Cost effectiveness of concurrent chemoradiation in comparison with radiation alone in locally advanced cervical cancer.

Introduction: Concurrent chemoradiation has been advocated to be more effective than radiation alone in the treatment of cervical cancer. However, it certainly has more side effects. Hence, it is worthwhile to investigate the cost-effectiveness (CE) of concurrent chemoradiation in comparison with radiation alone in locally advanced cervical cancer.

Prophylactic oral betamimetics for reducing preterm birth in women with a twin pregnancy.

Background: Twin pregnancies are associated with a high risk of neonatal mortality and morbidity due to an increased rate of preterm birth. Betamimetics can decrease contraction frequency or delay preterm birth in singleton pregnancies by 24 to 48 hours. The efficacy of oral betamimetics in women with a twin pregnancy is unproven.

Growth of breast-fed and formula-fed infants compared with national growth references of Thai children.

Objective: To compare the growth patterns of breast-fed (BF) and formula-fed (FF) infants with national growth references of Thai children and to determine whether the Thai growth references can be used to assess growth of BF infants who were fed according to Thai guidelines of infant feeding.

Design: Cohort study.

Material And Method: One hundred and fifty six term infants (78 BF and 78 FF infants) were followed prospectively for 12 months.

Random urinary protein-to-creatinine ratio for prediction of significant proteinuria in women with preeclampsia.

Objective: To evaluate the accuracy of random urinary protein-to-creatinine ratio for prediction of significant proteinuria in women with suspected preeclampsia.

Methods: A prospective study was conducted in hospitalized pregnant women with a suspicion of preeclampsia. Random mid-stream urine specimens were obtained for protein-to-creatinine ratio determination, and then participants were instructed to collect 24-h urine samples for protein measurement.

Antiemetic effect of ginger in gynecologic oncology patients receiving cisplatin.

To determine whether ginger had antiemetic effect in cisplatin-induced emesis, we conducted a randomized, double-blinded crossover study in 48 gynecologic cancer patients receiving cisplatin-based chemotherapy. Subjects were randomly allocated to regimen A or regimen B in their first cycle of the study. All patients received standard antiemetics in the first day of cisplatin administration.

Percutaneous versus open bone grafting in the treatment of tibial fractures: a randomized prospective trial.

Purpose: To compare the results between percutaneous bone grafting and open bone grafting of tibial shaft fractures.

Method: Thirty tibial fractured shafts with a delayed union or a high-energy tibial fractures which required early prophylaxis bone grafts were randomized to either percutaneous bone graft (n= 15) or open bone graft (n=15). One patient from the open bone graft group was lost to follow-up.

Nocardia pneumonia with empyema thoracis in a healthy neonate: a case report.

A 40-day-old male infant presented with fever and non-productive cough for 3 weeks, tachypnea and dyspnea 5 days before admission. The chest radiograph and computed tomographic (CT) scan revealed right lung consolidation with pleural effusion. Pleural tapping showed frank pus that grew Nocardia asteroides.

Effects of elephant garlic volatile oil (Allium ampeloprasum) and T-2 toxin on murine skin.

Effects of elephant garlic (Allium ampeloprasum) volatile oil (GVO) and trichothecene (T-2) toxin were studied in Swiss albino mice. The animals were 1) topically applied GVO, 2) topically applied T-2 toxin, 3) topically applied GVO followed by T-2 toxin (GVO/T-2), and 4) T-2 toxin application followed by GVO (T-2/GVO) on the right footpad. All animals were observed by Langerhans cell enumeration and pathological changes of the footpad on days 1, 3, 5 and 7.

Accuracy of frozen section in diagnosis of ovarian mass.

To determine the accuracy of frozen section according to the status of malignancy and the histologic cell type, we reviewed the frozen and permanent pathologic reports of 212 resected ovarian masses in our hospital. The accuracy, sensitivity, specificity, positive, and negative predictive value of frozen section were studied. The overall accuracy to determine the status of malignancy was 90.

Evaluation of the sensitivity of the double-contrast upper gastrointestinal series in the diagnosis of gastric cancer.

Objective: To evaluate the sensitivity, specificity and accuracy of the double-contrast upper gastrointestinal series (UGI series) in the diagnosis of gastric cancer.

Material And Method: The authors retrospectively reviewed the radiographs of the double-contrast UGI series for diagnosis of gastric cancer of 84 patients who had pathological confirmation by gastric biopsies and/or operations.

Results: The lesions were true positive in 45 patients, true negative in 28 patients, false positive in 8 patients and false nagative in 3 patients.

Methyldopa supplement for resistant essential hypertension: a prospective randomized placebo control crossover study.

Background: Resistant hypertension is an important public health problem, its prevalence varies between 30 to 50 per cent. However, there is no definite recommendation for the treatment of resistant hypertension (HT).

Material And Method: A prospective randomized placebo control crossover study in resistant HT was designed to compare safety and efficacy between methyldopa 250 mg twice daily and placebo using ambulatory blood pressure monitoring.

Squamous cell carcinoma arising from dermoid cyst: Case reports and review of literature.

Malignant transformation of a dermoid cyst is rare, with squamous cell carcinoma (SCC) being the most common type. During a 10-year period in our institution, we encountered only four cases of SCC out of 425 cases of dermoid cyst, an incidence of 0.94%.

Can we rely on the size of the lymph node in determining nodal metastasis in ovarian carcinoma?

This study endeavored to determine whether lymph node size is a reliable indicator in determining lymph node metastasis in common epithelial ovarian cancer. We reviewed pathologic sections of pelvic and para-aortic lymph nodes removed from 104 ovarian carcinoma patients who underwent either primary surgical staging or secondary surgery from January 1994 to July 2001. All sections of each individual node were measured in two dimensions.

Suprafibrous injection with corticosteroid in de Quervain's disease.

Between February 1996 and August 2001, 115 suprafibrous injections with corticosteroid were performed on 103 patients. Initial satisfactory result was found in 105 wrists (91.30%).

Blood pressure response to antihypertensive agents related to baseline blood pressure.

Prevalence of white-coat hypertension varies approximately 20 per cent among mild hypertensives. When white-coat hypertensives are prescribed antihypertensive medication, there is usually a decrease in clinic blood pressure (BP), but little or no change in 24 hours blood pressure (ABPM). The objective of the study was to test the hypothesis that efficacy of medication therapy for hypertension is identical in any grading of severity of baseline blood pressure.