A closer look at depression and sleep quality relation: A cross-sectional study of taxi drivers in Tabriz metropolis.

Background And Aim: Taxi drivers play a significant role in urban mobility and safety as professional drivers. They typically have poor incomes, long work hours, lack of sleep, and high levels of stress, which increase the risk of physical and mental illnesses. The goal of this study was to explore the relationship between sleep disorders and depression among Tabriz metropolis taxi drivers.

A nanoscale electrochemical guanine DNA-biosensor based on a flower-like nanocomposite of Tb-doped ZnO for the sensitive determination of pemetrexed.

Pemetrexed is an antineoplastic drug used in chemotherapeutic treatments, especially in malignant mesothelioma and non-small cell lung carcinoma, but can also cause a variety of complications, like stomach pain, nausea, burning, vomiting, numbness, and tingling, emphasizing the need for an approach to quantify the drug in biological matrices. Herein, a DNA-based biosensor was introduced for pemetrexed determination. A hydrothermal approach was used for synthesizing flower-like nanoparticles (NPs) of zinc oxide (ZnO) doped with Tb (FL-NP Tb/ZnO).

Prognosis of COVID-19 patients using lab tests: A data mining approach.

Background: The rapid prevalence of coronavirus disease 2019 (COVID-19) has caused a pandemic worldwide and affected the lives of millions. The potential fatality of the disease has led to global public health concerns. Apart from clinical practice, artificial intelligence (AI) has provided a new model for the early diagnosis and prediction of disease based on machine learning (ML) algorithms.

Eco-friendly synthesis of carbon nanotubes and their cancer theranostic applications.

Carbon nanotubes (CNTs) with attractive physicochemical characteristics such as high surface area, mechanical strength, functionality, and electrical/thermal conductivity have been widely studied in different fields of science. However, the preparation of these nanostructures on a large scale is either expensive or sometimes ecologically unfriendly. In this context, plenty of studies have been conducted to discover innovative methods to fabricate CNTs in an eco-friendly and inexpensive manner.

A label-free electrochemical biosensor based on 3D cubic Eu/CuO nanostructures with clover-like faces for the determination of anticancer drug cytarabine.

The present research utilized a simplified procedure for developing a novel electro-chemical DNA biosensor based on a carbon paste electrode (CPE) modified with three-dimensional (3D) cubic Eu/CuO nanostructures with clover-like faces (Eu/CuO CLFNs). The modified electrode was applied to monitor electro-chemical interactions between dsDNA and cytarabine for the first time. Then, the decreased oxidation signal of guanine following the interactions between cytarabine and dsDNA was utilized as an indicator for selectively determining cytarabine using differential pulse voltammetry (DPV).

Determination of halogenated hydrocarbons in urine samples using a needle trap device packed with Ni/Zn-BTC bi-MMOF the dynamic headspace method.

In this study, a nickel/zinc-BTC bi-metallic metal-organic framework (bi-MMOF) was employed as a new and efficient adsorbent in a needle trap device (NTD) for headspace (HS) sampling, extraction and analysis of halogenated hydrocarbons (trichloroethylene, tetrachloroethylene, chloroform, and tetrachloroethylene) from spiked and real urine samples. Characterization of the prepared adsorbent was accomplished by FT-IR, PXRD, EDX, elemental mapping, and FE-SEM techniques. According to experimental results, the optimal temperature and extraction time, salt content, temperature and desorption time of the response surface methodology (RSM) and Box-Behnken design (BBD) were determined to be 56 °C and 30 min, 5.

Quantum dots against SARS-CoV-2: diagnostic and therapeutic potentials.

The application of quantum dots (QDs) for detecting and treating various types of coronaviruses is very promising, as their low toxicity and high surface performance make them superior among other nanomaterials; in conjugation with fluorescent probes they are promising semiconductor nanomaterials for the detection of various cellular processes and viral infections. In view of the successful results for inhibiting SARS-CoV-2, functional QDs could serve eminent role in the growth of safe nanotherapy for the cure of viral infections in the near future; their large surface areas help bind numerous molecules post-synthetically. Functionalized QDs with high functionality, targeted selectivity, stability and less cytotoxicity can be employed for highly sensitive co-delivery and imaging/diagnosis.

Does propolis have any effect on rheumatoid arthritis? A review study.

Rheumatoid arthritis (RA) is a chronic autoimmune disease in which inflammation and oxidative stress play a key role in its pathophysiology. Complementary therapies along with medications may be effective in the control of RA. Propolis is a natural substance extracted from beehives, which have confirmed anti-inflammatory and antioxidant effects.

Effect of propolis supplementation on athletic performance, body composition, inflammation, and oxidative stress following intense exercise: A triple-blind randomized clinical trial.

Background: Emerging evidence indicates that propolis as a novel potential antioxidant has unique benefits. This study aimed to evaluate the effect of propolis on oxidative stress, inflammation, body composition, and athletic performance in healthy active subjects.

Methods: This clinical trial was conducted on 54 male military cadets.

Recent developments in voltammetric and amperometric sensors for cysteine detection.

This review article aims to provide an overview of the recent advances in the voltammetric and amperometric sensing of cysteine (Cys). The introduction summarizes the important role of Cys as an essential amino acid, techniques for its sensing, and the utilization of electrochemical methods and chemically modified electrodes for its determination. The main section covers voltammetric and amperometric sensing of Cys based on glassy carbon electrodes, screen printed electrodes, and carbon paste electrodes, modified with various electrocatalytic materials.

Simplification of gold nanoparticle synthesis with low cytotoxicity using a greener approach: opening up new possibilities.

Gold nanoparticles (AuNPs) have diverse applications in the diagnosis and treatment of ailments. This study describes an extremely simplified synthesis of AuNPs using antioxidant-rich pollen extract as a local natural source. Ultraviolet-visible (UV-vis) spectroscopy, X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR) and transmission electron microscopy (TEM) were used to characterize the synthesized AuNPs; strong UV-vis absorption at 534 nm confirmed their formation, the XRD pattern showed the presence of a crystalline structure, and TEM images showed them to be spherical nanoparticles with an average size of 9.

Nano-hydroxyapatite/polyaniline composite as an efficient sorbent for sensitive determination of the polycyclic aromatic hydrocarbons in air by a needle trap device.

Hydroxyapatite is a readily available, inexpensive, environmentally friendly adsorbent with high adsorption capacity. In this study, a polyaniline-doped nano-hydroxyapatite (PANI@HA) adsorbent was synthesized and employed in a needle trap device for the extraction of polycyclic aromatic hydrocarbons such as naphthalene, fluoranthene, benzo[]anthracene, phenanthrene, and benzo[]pyrene for the first time. The synthesized adsorbent was characterized by X-ray diffraction, field emission scanning electron microscopy, and Fourier-transform infrared spectroscopy analysis.

Simultaneous determination of methadone and morphine at a modified electrode with 3D β-MnO nanoflowers: application for pharmaceutical sample analysis.

The present research synthesized manganese dioxide nano-flowers (β-MnO-NF) a simplified technique for electro-catalytic utilization. Moreover, morphological characteristics and X-ray analyses showed Mn in the oxide form with β-type crystallographic structure. In addition, the research proposed a new efficient electro-chemical sensor to detect methadone at the modified glassy carbon electrode (β-MnO-NF/GCE).

Calcium carbonate nanowires: greener biosynthesis and their leishmanicidal activity.

The synthesis of inorganic rod shape nanostructures is important in chromatography, dentistry, and medical applications such as bone implants, and drug and gene delivery systems. Herein, calcium carbonate (CaCO) nanowires were synthesized using a plant extract and the ensuing nanoparticles were characterized by XRD, FESEM, and HR-TEM. Then, the leishmanicidal effects of biogenic calcium carbonate nanowires were investigated against including the toxicity of varying concentrations of nanoparticles, and the percentage of viable and apoptotic cells based on flow cytometry analysis.

anticancer activity of parent and nano-encapsulated samarium(iii) complex towards antimicrobial activity studies and FS-DNA/BSA binding affinity.

Based on the potential anticancer properties of lanthanide complexes, the anticancer activity of the Sm(iii) complex containing a 2,2'-bipyridine ligand (bpy) and its interaction with FS-DNA (Fish-Salmon DNA) and BSA (Bovine Serum Albumin) were examined experimentally and by molecular docking in this paper. Absorption and fluorescence spectroscopic methods were used to define the thermodynamic parameters, binding constant ( ), and the probable binding mechanism. It was concluded that the Sm complex interacts with FS-DNA through a minor groove with a of 10 M.

Metallic SPIONP/AgNP synthesis using a novel natural source and their antifungal activities.

The green synthesis of nanoparticles (NPs) is important because of the favorable potential of plant biomolecules involved in the synthesis of NPs. This study aimed to provide a fast, easy, cheap, and environmentally friendly method for the synthesis of superparamagnetic iron oxide NPs (SPIONP) and silver nanoparticles (AgNPs) using and an evaluation of their use as antifungal agents against and . The physicochemical properties of AgNPs and SPIONPs were studied using FESEM, HRTEM, XRD, VSM, UV-Vis, and EDX spectroscopy.

Parent and nano-encapsulated ytterbium(iii) complex toward binding with biological macromolecules, cytotoxicity, cleavage and antimicrobial activity studies.

To determine the chemotherapeutic and pharmacokinetic aspects of an ytterbium complex containing 2,9-dimethyl-1,10-phenanthroline (MePhen), binding studies were carried out with FS-DNA/BSA by employing multiple biophysical methods and a molecular modeling study. There are different techniques including absorption spectroscopy, fluorescence spectroscopy, circular dichroism studies, viscosity experiments (only in the case of DNA), and competitive experiments used to determine the interaction mode between DNA/BSA and the ytterbium-complex. The results showed that the Yb-complex exhibited a high propensity for the interaction of BSA and DNA hydrophobic interactions and van der Waals forces.

The synthesis, characterization, DNA/BSA/HSA interactions, molecular modeling, antibacterial properties, and cytotoxic activities of novel parent and niosome nano-encapsulated Ho(iii) complexes.

Based on the importance of metal-centered complexes that can interact with DNA, this research focused on the synthesis of a new Ho(iii) complex. This complex was isolated and characterized elemental analysis, and FT-IR, fluorescence, and UV-vis spectroscopy. Additional confirmation of the Ho(iii) complex structure was obtained single-crystal X-ray diffraction.

Applications of nano-materials in diverse dentistry regimes.

Research and development in the applied sciences at the atomic or molecular level is the order of the day under the domain of nanotechnology or nano-science with enormous influence on nearly all areas of human health and activities comprising diverse medical fields such as pharmacological studies, clinical diagnoses, and supplementary immune system. The field of nano-dentistry has emerged due to the assorted dental applications of nano-technology. This review provides a brief introduction to the general nanotechnology field and a comprehensive overview of the synthesis features and dental uses of nano-materials including current innovations and future expectations with general comments on the latest advancements in the mechanisms and the most significant toxicological dimensions.

Efficient extraction of aromatic amines in the air by the needle trap device packed with the zirconium based metal-organic framework sorbent.

In this study, development of a needle trap device (NTD) packed with UiO-66 adsorbent was used for the sampling of the aromatic amine compounds (including aniline, ,-dimethylaniline and -toluidine) followed by gas chromatography (GC) with flame-ionization detector (FID) analysis. The UiO-66 sorbent was synthesized and then packed inside a spinal needle (Gauge 22). The synthesized sorbent was characterized with the XRD, FE-SEM, EDS and FT-IR techniques.

Nickel-doped cerium oxide nanoparticles: biosynthesis, cytotoxicity and UV protection studies.

This study was conducted to obtain Ni Ce O (where = 0, 1, 3 and 5% w/w) nanoparticles using extracts through an easy, inexpensive and non-toxic method. The biosynthesized nanoparticles have been characterized powder X-ray diffraction (PXRD), Raman spectroscopy, field emission scanning electron microscopy (FESEM), energy dispersive X-ray (EDX) spectroscopy, and vibrating-sample magnetometer (VSM) analysis. The results of PXRD showed that Ni doping in the CeO process generated a higher shift at an angle of (111); also, the PXRD patterns were surveyed by the Rietveld refinement technique.