1,761 results match your criteria: "Baltimore National Study Center for Trauma & EMS[Affiliation]"

Objectives: To describe and enumerate surgeries for patients who underwent reconstruction or amputation after severe distal tibia, ankle, and mid to hindfoot injuries.

Methods: Design: Secondary analysis of a multicenter prospective observational study.

Setting: 31 U.

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Sedation Practices in Mechanically Ventilated Neurocritical Care Patients from 19 Countries: An International Cohort Study.

Neurocrit Care

January 2025

Division of Neuroscience Critical Care, Departments of Neurology, Neurosurgery, and Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Background: Our objective was to characterize the impact of common initial sedation practices on invasive mechanical ventilation (IMV) duration and in-hospital outcomes in patients with acute brain injury (ABI) and to elucidate variations in practices between high-income and middle-income countries.

Methods: This was a post hoc analysis of a prospective observational data registry of neurocritically ill patients requiring IMV. The setting included 73 intensive care units (ICUs) in 18 countries, with a total of 1,450 patients with ABI requiring IMV.

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Sleep-wake disturbances frequently present in Veterans with mild traumatic brain injury (mTBI). These TBI-related sleep impairments confer significant burden and commonly exacerbate other functional impairments. Therapies to improve sleep following mTBI are limited and studies in Veterans are even more scarce.

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Incarceration is associated with higher mortality after trauma: An unreported health care disparity.

J Trauma Acute Care Surg

January 2025

From the Division of Plastic and Reconstructive Surgery, Department of Surgery (H.N.-P.), Albany Medical Center, Albany, New York; Johns Hopkins Bloomberg School of Public Health (H.N.-P., E.R.H.); Division of Acute Care Surgery, Department of Surgery (J.P.B., E.R.H.), Johns Hopkins Medicine, Baltimore, Maryland; Division of General Surgery, Department of Surgery (J.P.B.), University of British Columbia, Vancouver, British Columbia, Canada; and Department of Plastic and Reconstructive Surgery (C.S.H.), WakeMed Health and Hospitals, Raleigh, North Carolina.

Background: While the United States has the highest incarceration rate worldwide, at nearly 1% of the adult population (more than 2 million people), insights regarding health disparities in this population remain limited. This retrospective cohort study represents the largest national database analysis of incarcerated trauma patients to date and investigates whether incarceration status is an independent risk factor for poor outcomes after trauma for US adults.

Methods: We analyzed data from the National Trauma Data Bank from 2017 to 2018.

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Background: Anterior labroligamentous periosteal sleeve avulsion (ALPSA) lesions are associated with recurrent shoulder instability and higher rates of failure after capsulolabral repair compared with similarly treated Bankart lesions. Although these lesions can portend poor outcomes, there are limited data on the associated conditions and postoperative course in a young, active population.

Purpose: To evaluate the mid- to long-term clinical course and failure rates after ALPSA repairs and assess features associated with these outcomes.

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Associations of Traumatic Brain Injury and Hearing: Results From the Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS).

J Head Trauma Rehabil

December 2024

Author Affiliations: Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania (Dr Schneider); Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania (Dr Schneider); Department of Psychiatry and Behavioral Sciences, School of Medicine, Johns Hopkins University, Baltimore, Maryland (Dr Kamath); Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland (Drs Reed, Sharrett, Lin, and Deal); The MIND Center, University of Mississippi Medical Center, Jackson, Mississippi (Dr Mosley); National Institute of Neurological Disorders and Stroke Intramural Research Program, Bethesda, Maryland (Dr Gottesman); Department of Otolaryngology, School of Medicine, Johns Hopkins University, Baltimore, Maryland (Drs Lin and Deal); and Cochlear Center for Hearing and Public Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland (Drs Lin and Deal).

Objective: To examine associations of traumatic brain injury (TBI) with self-reported and clinical measures of hearing function.

Setting: Four US communities.

Participants: A total of 3176 Atherosclerosis Risk in Communities Study participants who attended the sixth study visit in 2016-2017, when hearing was assessed.

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E-cigarette/vaping-associated lung injury (EVALI) is strongly associated with vitamin E acetate and often occurs with concomitant tetrahydrocannabinol (THC) use. To uncover pathways associated with EVALI, we examined cytokines, transcriptomic signatures, and lipidomic profiles in bronchoalveolar lavage fluid (BALF) from THC-EVALI patients. At a single center, we prospectively enrolled mechanically ventilated patients with EVALI from THC-containing products (N = 4) and patients with non-vaping acute lung injury and airway controls (N = 5).

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Prevalence of Disability Among Older Adults in Prison.

JAMA Netw Open

December 2024

Department of Health Policy and Management, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, Maryland.

Importance: The number of older adults in long-term correctional facilities (prisons) has increased rapidly in recent years. The cognitive and functional status of this population is not well understood due to limitations in the availability of longitudinal data.

Objective: To comparatively examine the prevalence and disability status of the population of adults 55 years and older in prisons and adults living in community settings for a 14-year period (2008-2022).

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Is trauma associated with plant-based diet choice?

Appetite

December 2024

VA Boston Healthcare System, 150 South Huntington, Boston, MA, 02130, USA; National Center for PTSD, 150 South Huntington, Boston, MA, 02130, USA; Boston University School of Medicine, 72 East Concord St. Boston, MA, 02118, USA. Electronic address:

Examinations of links between plant-based diets (e.g., vegetarian and vegan diets) and indices of physical and mental health have received increased attention in the scientific literature in recent years.

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Background: Previous research has estimated that over one-half of patients with orthopaedic trauma experience financial distress after the injury. However, it is unknown what proportion of patients lived under financial distress before the injury and, therefore, the causal effect of the injury on financial distress. This study examined changes in financial distress after the injury and factors associated with new post-injury financial distress.

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Background: Emergency/trauma radiology artificial intelligence (AI) is maturing along all stages of technology readiness, with research and development (R&D) ranging from data curation and algorithm development to post-market monitoring and retraining.

Purpose: To develop an expert consensus document on best research practices and methodological priorities for emergency/trauma radiology AI.

Methods: A Delphi consensus exercise was conducted by the ASER AI/ML expert panel between 2022-2024.

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Purpose: We tested whether residents would improve in fluoroscopy knowledge and ability after using an inexpensive novel pelvis model and educational website.

Methods: Twenty-four orthopaedic residents were recruited from three United States residency programs and randomised into two groups with equal numbers of juniors and seniors. The OrthoAcademy group received educational materials from a website ( www.

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Objective: There is a paucity of high-quality return-to-play (RTP) data following treatment of cervical spine injuries in contact sports. In this study, the authors gathered insights from National Football League (NFL) team spine surgeon consultants to highlight current practices in treating cervical spine injuries and report decision-making regarding RTP in professional American football players.

Methods: A cross-sectional, online survey was distributed to all NFL consulting physicians specializing in the management of spine injuries.

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Article Synopsis
  • The study explores the biological differences linked to PTSD by examining DNA methylation changes in blood, suggesting they could indicate susceptibility or effects of trauma.
  • Conducted by the Psychiatric Genomics Consortium, the research included nearly 5,100 participants to identify specific genetic markers associated with PTSD.
  • Results showed 11 significant CpG sites related to PTSD, with some also showing correlations between blood and brain tissue methylation, highlighting their potential role in understanding PTSD biology.
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Background: In June 2021, the Injury Research Engagement Project (I-REP) was established. In 2022, we preformed focus group analysis with patients/caregiver and researchers that resulted in themes in preferences, motivations, and best practices to increase participation in trauma research. The importance of trust and well-established relationships was common across all groups.

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Several reports revealed that oxidative stress was involved in the mouse model of nonsteroidal anti-inflammatory drug (NSAIDs)-induced small intestinal mucosal injuries. Thus, we aimed to investigate in the prospective clinical study, that the relevance of oxidative stress balance in small intestinal mucosal injury in NSAIDs users. We prospectively included 60 patients who had been taking NSAIDs continuously for more than 3 months and exhibited obscure gastrointestinal bleeding (number UMIN 000011775).

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Purpose: This study aims to explore demographic disparities, regional and institutional variations, surgical timing, narcotic use, and management trends in neonatal brachial plexus palsy (NBPP) patients due to limited published literature.

Methods: We conducted a retrospective cohort study using the Pediatric Health Information System (PHIS) database of NBPP patients who underwent surgery within the first 2 years of life. Patients were stratified into two groups based on age at surgery: ≤ 8 months and > 8 months.

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Background: Hamstring injuries can have a significant burden on a professional football player's career and performance. One in 4 players will suffer a lower extremity strain in their career, with the hamstring being the most common. These injuries are often fraught with extended periods of recovery and reinjury rates varying between 16% and 38%.

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Article Synopsis
  • The text discusses the importance of forecasting future health issues in the USA for effective planning and public awareness regarding disease and injury burdens.
  • It describes the methodology for predicting life expectancy, cause-specific mortality, and disability-adjusted life-years (DALYs) from 2022 to 2050 using the Global Burden of Diseases framework.
  • The forecasting includes various scenarios to assess the potential impacts of health risks and improvements across the country, focusing on demographic trends and health-related risk factors.
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Background: Sexual orientation discrimination increases the risks of negative health outcomes for sexual minorities. Previous studies have found increased rates of eating disorder symptoms in sexual minority individuals, which is attributable to minority stress and discrimination that they experience. Emerging research suggests relationships between sexual orientation discrimination and eating disorder symptoms.

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Article Synopsis
  • Major depressive disorder (MDD) includes a challenging subset known as treatment-resistant depression (TRD), which can be effectively targeted using rapid-acting antidepressants such as ketamine and esketamine, though individual responses vary.
  • Research is focusing on identifying clinical predictors for better treatment outcomes with ketamine/esketamine, including factors like family history of alcohol use and history of childhood trauma, as well as potential brain-based biomarkers detected through EEG.
  • Most response predictors show modest effects, thus future studies should employ multivariate models and standardize biomarker collection methods to improve the robustness and comparability of findings across trials.
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Article Synopsis
  • - Chronic opioid use (COU) following traumatic injuries is a health issue globally, impacting recovery and heightening the risk of long-term dependence, with a specific study conducted in South Korea highlighting the prevalence and associated factors.
  • - In analyzing data from over 1 million individuals, the study found that 13.5% of trauma patients and 12.6% of non-trauma patients were chronic opioid users, indicating a slightly higher risk should one experience a traumatic injury.
  • - Significant risk factors for COU included older age (especially those aged 65 and older) and prior opioid use, suggesting a need for further research to minimize risks related to opioid prescriptions in South Korea.
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The burden of alcohol and substance use disorders in adolescents and young adults.

Drug Alcohol Depend

January 2025

Division of Gastroenterology and Hepatology, Department of Medicine, University of Arizona College of Medicine, Phoenix, AZ, USA; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Banner University Medical Center, Phoenix, AZ, USA; BIO5 Institute, University of Arizona College of Medicine-Phoenix, Phoenix, AZ, USA. Electronic address:

Article Synopsis
  • * Analysis of Global Burden of Disease Study 2019 data shows a geographical concentration of SUD issues in Europe and the Americas, with males being more affected than females.
  • * The research emphasizes the urgent need for effective policies to address the substantial burden of SUDs among AYAs, particularly focusing on alcohol-related harms like injuries and violence.
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Article Synopsis
  • This study focused on understanding how common diagnostic uncertainty is when critically ill children are admitted to Pediatric Intensive Care Units (PICUs) and what factors contribute to it.
  • Researchers reviewed medical records from 882 pediatric patients across four hospitals to assess the presence of diagnostic uncertainty at admission and how it changed by the time of discharge.
  • Key findings indicated that 25.9% of patients showed diagnostic uncertainty upon PICU admission, with significant factors being the time of admission, illness severity, atypical symptoms, and discrepancies in diagnoses between different healthcare providers.
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