1 results match your criteria: "Bakirkoy Research and Training Hospital for Neurology and Psychiatry[Affiliation]"
Matrix metalloproteinases and their tissue inhibitors in relapsing remitting multiple sclerosis: Possible markers and treatment agents.
Ideggyogy Sz
January 2021
Department of Neurology, Bakirkoy Research and Training Hospital for Neurology and Psychiatry, Istanbul, Turkey.
Background And Purpose: Matrix metalloproteinases (MMPs), which are synthesized by many cell groups and responsible for the destruction of matrix proteins, and endogen tissue inhibitors of MMPs (TIMPs) have a role in the pathogenesis of Multiple Sclerosis (MS) by affecting the blood-brain barrier. We aimed to investigate the role of MMPs and TIMPs in the immunopathogenesis and in the course of multiple sclerosis (MS).
Methods: We enrolled 25 relapsing remitting MS patients, who had a definite MS diagnosis according to McDonald criteria and 25 healthy subjects similar for age and gender as control group.