Evaluation of risk factors for postpartum cerebral venous sinus thrombosis, a multicenter retrospective observational study.

The postpartum period is a well-defined risk factor for cerebral venous sinus thrombosis (CVST). However, it is unclear which patients are at risk for CVST in the postpartum period. Thus, determining some CVST risk factors in postpartum patients may be useful for preventing the disorder in this population.

Is Unilateral Extended Pterional Craniotomy Adequate Instead of Bicoronal (Bifrontal) Craniotomy in Large or Giant Olfactory Groove Meningiomas?

Aim: To evaluate the radiological characteristics, clinical features,and surgical outcomes of bicoronal incision and bifrontal craniotomy for olfactory groove meningiomas (OGMs).

Material And Methods: This was a retrospective review of 16 patients (nine male and seven female) with large and giant OGMs operated through unilateral extended pterional craniotomy between 2010 and 2022. The radiological characteristics, clinical features,and surgical outcomes were examined.

Hoyeraal-Hreidarsson syndrome: a case report of dyskeratosis congenita with a novel PARN gene mutation.

Introduction And Importance: Dyskeratosis congenita (DC) is a rare multisystem disorder primarily characterized by bone marrow failure due to telomere shortening. Typical clinical features include oral leukoplakia, skin hyperpigmentation, and nail dystrophy, along with an increased risk of malignancies. Hoyeraal-Hreidarsson syndrome (HH), a severe variant of DC, is associated with profound neurological and immunological complications, emphasizing the importance of early diagnosis and genetic evaluation to guide appropriate management.

Associations between stages of diabetic polyneuropathy and quality of life, neuropathic pain, and well-being: A multicenter, cross-sectional analysis based on electroneuromyographic findings.

Aim: This study aimed to investigate the relationship between electrophysiological findings of diabetic neuropathy (DN) and patients' quality of life, neuropathic pain levels, and well-being.

Materials And Methods: A cross-sectional study was conducted in 12 centers in Turkey. DN patients were categorized into four stages based on electrophysiological findings using the Baba classification.

Effects of tDCS on glutamatergic pathways in epilepsy: neuroprotective and therapeutic potential.

Epilepsy is a chronic neurological disease characterized by recurrent seizures caused by abnormal electrical activity in the brain. The aim of our study was to investigate the effect of tDCS on oxidative stress, Ca, glutamate, GABA, AMPAR1, and NMDAR1 levels in kindling-induced epilepsy model. Behavioral tests evaluated motor and cognitive functions, while assessing oxidative stress, Ca, glutamate, GABA, AMPAR1, and NMDAR1 levels in hippocampal tissue.

Validity and Reliability of the Turkish Version of the Medial Tibial Stress Syndrome Score.

Background: Medial tibial stress syndrome (MTSS) is a common leg injury in military personnel and athletes and is especially related to running and jumping. A patient-reported outcome measure, the MTSS score, was developed to determine the severity of MTSS.

Purpose: To translate, culturally adapt, and validate the MTSS score for the Turkish language.

Retinal Vascular Changes in Vitiligo: A Novel Approach Using OCTA.

Purpose: This study aimed to the detect of structural and functional changes in the retina and choroid in patients with vitiligo using optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA).

Materials And Methods: Thirty patients with vitiligo and 30 healthy participants were enrolled in the study. Central macular thickness (CMT), retina nerve fiber layer (RNFL) thickness, choroidal thickness (CT), foveal avascular zone (FAZ) area, and superficial and deep vascular density (VD) ratios were compared between the groups.

An interpretable framework for inter-observer agreement measurements in TILs scoring on histopathological breast images: A proof-of-principle study.

Breast cancer, a widespread and life-threatening disease, necessitates precise diagnostic tools for improved patient outcomes. Tumor-Infiltrating Lymphocytes (TILs), reflective of the immune response against cancer cells, are pivotal in understanding breast cancer behavior. However, inter-observer variability in TILs scoring methods poses challenges to reliable assessments.

Urinary Neurotrophin Levels as Potential Biomarkers for Overactive Bladder: A Prospective Study.

Background: Overactive bladder (OAB) is an issue in the field of urology that is known for causing symptoms like urges to urinate frequently during the day and even at night (known as nocturia). Nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) play a vital role in the growth and operation of nerve cells in the body. New studies are indicating a connection between these neurotrophins and OAB; As such this research project was undertaken to explore how levels of NGT and BDNF in urine might be related to the presence of OAB in individuals.

Reliability and quality of information provided by artificial intelligence chatbots on post-contrast acute kidney injury: an evaluation of diagnostic, preventive, and treatment guidance.

Objective: The aim of this study was to evaluate the reliability and quality of information provided by artificial intelligence chatbots regarding the diagnosis, preventive methods, and treatment of contrast-associated acute kidney injury, while also discussing their benefits and drawbacks.

Methods: The most frequently asked questions regarding contrast-associated acute kidney injury on Google Trends between January 2022 and January 2024 were posed to four artificial intelligence chatbots: ChatGPT, Gemini, Copilot, and Perplexity. The responses were evaluated based on the DISCERN score, the Patient Education Materials Assessment Tool for Printable Materials score, the Web Resource Rating scale, the Coleman-Liau index, and a Likert scale.

Monitoring the effect of antiviral treatment on the development of cirrhosis and hepatocellular carcinoma in chronic hepatitis B patients.

Objective: Despite the availability of treatment and vaccines for chronic hepatitis B infection, it remains a public health problem. The use of nucleos(t)ide antiviral agents is effective in preventing complications such as cirrhosis and hepatocellular carcinoma, but despite the reduction, the risk persists. The objective of this study was to assess alterations in aspartate aminotransferase to platelet ratio index and Fibrosis-4 scores and examine the effectiveness of risk estimates for HCC in chronic hepatitis B scores in predicting the risk of hepatocellular carcinoma among chronic hepatitis B patients undergoing prolonged antiviral treatment.

Impact of CD40 (rs1883832) and CD40L (rs1126535) gene variants on laryngeal cancer susceptibility and their association with serum biomarker levels of sCD40 and sCD40L.

Introduction: The most prevalent head and neck cancer type is laryngeal cancer. Laryngeal cancer susceptibility is increased by a combination of genetic variables and environmental factors. Genetic predispositions that influence the functioning of the immune system can affect tumor development.

Validation of the Turkish Version of the Professional Fulfillment Index.

Introduction: Clinician burnout represents a significant occupational hazard among physicians, with a notably high prevalence among emergency physicians. The Stanford Professional Fulfillment Index (PFI) was developed to comprehensively assess various aspects of doctors' work experiences, including professional fulfillment. In this study we aimed to validate the Turkish version of the PFI (T-PFI), a 16-item instrument designed to measure physicians' professional fulfillment and burnout.

Before and After Covid-19: What Has Changed in HIV Knowledge Level?

Introduction: The most essential way to prevent the transmission of Human Immunodeficiency Virus (HIV), one of the most important communicable diseases, is to enhance public knowledge. Our study aimed to assess whether there were any changes in HIV knowledge following the onset of the Covid-19 pandemic.

Methods: In Turkey, information stands were established in Izmir on 1 December 2017 and in public locations in both Istanbul and Izmir on 1 December 2021 to providing education the public about HIV/AIDS.

Predicting Short-Term Mortality in Patients With Acute Pulmonary Embolism With Deep Learning.

Background: Accurate prediction of short-term mortality in patients with acute pulmonary embolism (PE) is critical for optimizing treatment strategies and improving patient outcomes. The Pulmonary Embolism Severity Index (PESI) is the current reference score used for this purpose, but it has limitations regarding predictive accuracy. Our aim was to develop a new short-term mortality prediction model for PE patients based on deep learning (DL) with multimodal data, including imaging and clinical/demographic data.

Combined arm-leg endurance training vs. leg endurance training in patients with an implantable cardioverter defibrillator: A randomized controlled study.

Background: There is a lack of evidence regarding the effect of combining arm and leg training on arm exercise capacity, upper extremity functionality and safety in patients with implantable cardioverter-defibrillators (ICDs).

Objective: The aim of this study was to compare the effects of combined arm-leg endurance training (ET) with leg endurance training (ET) alone on arm exercise capacity, cardiorespiratory fitness, and safety issues in patients with ICDs.

Methods: In this prospective randomized controlled study, 24 caucasian patients with an ICD (NYHA class II-III, mean age: 59.

Fungal sinusitis due to mucormycosis in a diabetic immunosuppressed patient with acute myeloid leukemia (AML).

Introduction: Mucormycosis is an acute onset, invasive, fungal infection, characterized by organ involvement, and caused by Mucor, Rhizopus, or Absidia. Our aim was to present a case of mucormycotic infection and emphasize its importance in a diabetic immunosuppressed patient with acute myeloid leukemia (AML).

Case Presentation: A 68-year-old hypertensive and diabetic male patient with a diagnosis of AML developed respiratory failure and exhibited diffuse bilateral consolidation in high-resolution computed tomography (HRCT).

Rib fracture characteristics increasing the risk of hemothorax: a multicenter study.

The precise assessment of hemothorax risk resulting from a rib fracture is not feasible. CT images, patient characteristics, and clinical experience are utilized in daily practice to assess risk intuitively. This study aimed to identify specific markers on CT images that can predict the risk of hemothorax.