Vitamin B12, folate, and homocysteine levels in patients with obsessive-compulsive disorder.

It is known that elevated serum homocysteine, decreased folate, and low vitamin B12 serum levels are associated with poor cognitive function, cognitive decline, and dementia. Current literature shows that some psychiatric disorders, mainly affective and psychotic ones, can be related to the levels of vitamin B12, folate, and homocysteine. These results can be explained by the importance of vitamin B12, folate, and homocysteine in carbon transfer metabolism (methylation), which is required for the production of serotonin as well as for other monoamine neurotransmitters and catecholamines.

Tobacco use among 10th grade students in Istanbul and related variables.

Aim of this study was to determine prevalence of cigarette smoking and hookah use among 10th grade students in Istanbul, Turkey, and to compare sociodemographic, psychological and behavioral variables according to frequency of tobacco use. Cross-sectional online self-report survey conducted in 45 schools from the 15 districts in Istanbul/Turkey. The questionnaire included sections about demographic data, family characteristics, school life, psychological symptoms and use of substances including tobacco, hookah, alcohol, marijuana, volatiles, heroin, cocaine, non-prescribed legal tranquillizers (benzodiazepines, alprazolam etc.

Relationships of personality dimensions with impulsivity in alcohol-dependent inpatient men.

Background: Impulsivity is closely related to substance use and abuse, both as a contributor to use and as a consequence of use. Particular dimensions of temperament and character were reported to be associated with trait impulsivity in different populations.

Aim: The aim of the present study was to evaluate the relationship of personality dimensions with impulsivity among men with alcohol dependence.

Personality dimensions in male patients with early-onset alcohol dependence who seek treatment.

Aims: The aim of this study is to examine the capacity of different personality dimensions to predict early-onset alcoholism (EOA).

Methods: Participants were 176 consecutively admitted male inpatient alcohol dependents. Patients were grouped as EOA (onset before age 25) and late onset alcoholism (LOA).

Social anxiety and dissociation among male patients with alcohol dependency.

The aim of this study was to investigate the relationship between social anxiety and dissociation among male patients with alcohol dependency. Participants were 176 male patients consecutively admitted to an alcohol dependency treatment unit. The Liebowitz Social Anxiety Scale, the Dissociative Experiences Scale, the Beck Depression Inventory, the Spielberger State and Trait Anxiety Inventory, the Michigan Alcoholism Screening Test, and the Symptom Checklist-90-Revised were administered to all participants.

Alexithymia and personality dimensions in relation to depression and anxiety in male alcohol-dependent inpatients.

Objective. The aim of this study was to determine the relationship of alexithymia and temperament and character model of personality with depression and anxiety symptoms in detoxified male alcohol-dependent inpatients. Method.

Effect of therapy on motor cortical excitability in Parkinson's disease.

Objective: To assess the impact of the disease stage and therapy on motor cortical excitability in Parkinson's disease (PD).

Methods: Twenty newly diagnosed and medication-free, early stage patients, 20 late stage patients under antiparkinsonian therapy and 20 normal healthy controls were included. Motor threshold (MT), amplitudes of motor evoked potential (MEP), motor evoked potential amplitude/compound muscle action potential amplitude (MEP/CMAP) ratio, central motor conduction time (CMCT) and cortical silent period (CSP) were measured by stimulation of the motor cortex using a 13.

Dissociation and alexithymia among men with alcoholism.

Aim: The aim of the present study was to evaluate the relationship between alexithymia and dissociation among men with alcoholism.

Methods: Participants were 176 patients consecutively admitted to the inpatient unit of a addiction treatment center. The Toronto Alexithymia Scale, the Symptom Checklist-Revised, the Dissociative Experiences Scale, the Beck Depression Inventory, the Spielberger State-Trait Anxiety Inventory, and the Michigan Alcoholism Screening Test were administered to all participants.

Dissociative disorders among alcohol-dependent inpatients.

The aim of this study was to determine the prevalence of dissociative disorders among inpatients with alcohol dependency. The Dissociative Experiences Scale was used to screen 111 alcohol-dependent patients consecutively admitted to the inpatient unit of a dependency treatment center. Subgroups of 29 patients who scored 30.

Motor and occipital cortex excitability in migraine patients.

Objective: We evaluated motor and occipital cortex excitability in migraine patients using transcranial magnetic stimulation.

Methods: In this study, we included 15 migraine patients with aura (MwA), 15 patients without aura (MwoA) between attacks, and 31 normal healthy controls. Motor thresholds at rest, amplitudes of motor evoked potentials, central motor conduction time and cortical silent period were measured by stimulation of the motor cortex by using 13.

Substance abuse amplifies the risk for violence in schizophrenia spectrum disorder.

The factors responsible for the association between schizophrenia and violence with or without co-occurring substance abuse have not been fully elucidated. The present study had two aims: (1) ascertain whether substance abuse augments the risk for violence in patients with schizophrenia; and, (2) determine whether violence is differentially related to positive and negative symptoms of schizophrenia. A sample of 133 adults were participated in this study.

Dissociative disorders among inpatients with drug or alcohol dependency.

Objective: To determine the prevalence of dissociative disorders among inpatients with alcohol or drug dependency.

Method: The Dissociative Experiences Scale was used to screen 215 consecutive inpatients admitted to the dependency treatment center of a large mental hospital over a 1-year period (March 1, 2003, to March 31, 2004). Patients who had scores of 30.

Menstrually related symptom changes in women with treatment-responsive bipolar disorder.

Objective: In the present study, we aimed to evaluate menstrually related symptom changes in euthymic women with treatment-responsive bipolar disorder (BD) compared with healthy control subjects and investigate the presence of premenstrual dysphoric disorder (PMDD).

Methods: Thirty-four euthymic women with treatment-responsive BD on mood-stabilizers (lithium and/or valproate) for at least 6 months and 35 control subjects with no history of medical/mental disorder between ages of 18 and 35 years with regular menstrual cycles were prospectively followed up for at least two consecutive menstrual cycles using the Daily Record of Severity of Problems-Short Form (DRSP). Each subject was administered the retrospective self-report questionnaire, Premenstrual Assessment Form (PAF), in the first postmenstrual phase of the menstrual cycle.

Substance abuse and associated psychosocial risk factors among Turkish male adolescents.

This study reports the validation of the Drug Use Screening Inventory (DUSI) in a sample of Turkish youth. Clinical cases (N=90) were recruited from the inpatient and outpatient addictions treatment facility at Bakirkoy State Hospital for Psychiatric and Neurological Diseases in Istanbul, Turkey. Nonclinical cases (N=68) were recruited from the community by direct invitation from the researchers and advertisement.

Comparison of clinical characteristics in good and poor insight obsessive-compulsive disorder.

Beginning with DSM-III-R, the condition of an intact insight towards obsessive-compulsive symptoms, which was essential for the classical definition of obsessivecompulsive neurosis, has been removed, permitting inclusion of cases with poor insight. A total of 94 cases who met DSM-III-R criteria for obsessive-compulsive disorder were included in this study. The Structured Clinical Interview for DSM-III-R (SCID-P), YaleBrown Obsessive Compulsive Scale (Y-BOCS), Hamilton Rating Scale for Depression (HRSD), Hamilton Rating Scale for Anxiety (HRSA), and State-Trait Anxiety Inventory (STAI) were administered to each patient.

Cortical silent period following transcranial magnetic stimulation in epileptic patients.

Cortical silent period (SP) following transcranial magnetic stimulation is mainly due to cortical inhibitory mechanisms. SP may have a value for detecting inhibitory mechanisms in epileptic patients with or without treatment. The aim of this study was to evaluate the effect of both the epilepsy and the antiepileptic medication on these inhibitory mechanisms.

Auditory event-related potentials (P300) in partial and generalized epileptic patients.

We evaluated the P300 components of event-related potentials (ERP) in 64 cryptogenic partial epilepsy (CPE) patients, and 52 idiopathic generalized epilepsy (IGE) patients as well as in their age-matched control groups. The P200, N200 and P300 latencies recorded from Cz were significantly longer in CPE patients compared with those of their control group (P = 0.0371, P = 0.

Lesion localization in developing poststroke hand dystonia.

Reports of 9 cases with hand dystonia due to stroke are described. The site of the lesion was found to be parietothalamic in 1 patient, posterolateral thalamic in 5 patients, dorsal thalamic in 2 patients and medial thalamic in 1 patient as defined by computerized tomography or magnetic resonance imaging. In addition to the hand dystonia, hemiballism was noted in 1 case, hemichorea in 2 cases, action tremor in 3, anxiety in 3 and pain in 2 cases.