A case report of refractory immune thrombocytopenia: Challenges in choice of therapies in resource limiting center.

Introduction And Importance: Refractory immune thrombocytopenic purpura (ITP) is a rare but serious condition causing significant morbidity and mortality due to inadequate response to standard treatments, resulting in persistent thrombocytopenia and increased bleeding risk.

Case Presentation: An 18-year-old female patient, diagnosed with ITP two years prior following excessive vaginal bleeding and fatigue, was initially treated with oral prednisolone for two months and discharged in improved condition. Eighteen months after treatment cessation, she presented with recurrent excessive vaginal bleeding, intermittent bilateral nasal bleeding, skin rash, blurred vision, fatigue, tinnitus, vertigo, and intermittent headaches (one-month duration).

Internal hernia through mesoappendix causing small bowel obstruction: A case report.

Introduction: Intestinal obstruction is one of causes of acute abdomen leading to laparotomy. Even though there are different causes of small bowel obstruction (SBO), internal hernia is a rare one. Though different types of internal hernias occur, herniation through the mesoappendix is reported only four times in the literature.

Perioperative mortality of caesarean section in North-West Ethiopia: a prospective cohort study.

Objective: This study aimed to assess 7-day perioperative maternal mortality and risk factors at Tibebe Ghion Specialized Hospital.

Design: A single-centre prospective cohort study.

Setting: A tertiary hospital in North-West Ethiopia, 01 June 2019 to 30 June 2021.

Vaccines coverage and associated factors among children aged 12-23 months in the Pawie district, Ethiopia: A cross-sectional study.

Background: Although access to vaccines for children is increasing at healthcare facilities, outbreaks of vaccine preventable diseases and deaths have been reported in different areas of the Benishangul Gumuz region, in Ethiopia. Various interventions have been designed to provide vaccines for each child at an appropriate age. Still there is limited information on full vaccination coverage and associated factors among children aged 12-23 months in the Benishangul-Gumuz region, particularly in the Pawie district.

A serial mediation model of Big 5 personality traits, emotional intelligence, and psychological capital as predictors of teachers' professional well-being.

This study aimed to explore the relationship among the Big Five personality traits, emotional intelligence (EIQ), psychological capital (PsyCap), and teacher well-being (TPWB) within the context of higher education. The objective was to predict TPWB in university teachers by utilizing the Big Five personality traits and PsyCap while considering EI as a mediator. Data were collected from 708 teachers in Ethiopian higher education institutions.

Prospective study on functional outcome of distal femur fracture treated by open reduction and internal fixation using distal femur locking plate in Tibebe Ghion Specialized Hospital, Bahirdar, North West Ethiopia.

Background: Distal femur fractures account for 6% of femur fractures. The treatment of distal femur fractures is challenging. Historically, nonoperative management has been the mainstay of management, which has evolved to operative management.

Multivariate analysis of phenotypic diversity elite bread wheat (.) genotypes from ICARDA in Ethiopia.

Wheat is an important crop for food security, providing a source of protein and energy for the growing population in Ethiopia. However, both biotic and abiotic factors limit national wheat productivity. The availability of genetically diverse wheat genotypes is crucial for developing new wheat varieties that are both high-yielding and resilient to stress.

A 14-year-old male patient with diagnosis of Prader-Willi syndrome in Ethiopia: a case report.

Background: Prader-Willi syndrome is a complex multisystem disorder due to the absent expression of paternally active genes in the Prader-Willi syndrome-critical region on chromosome 15 (15q11.2-q13). The main clinical features are hyperphagia (which frequently results in early-onset obesity), hypogonadism, developmental delays, typical behaviors (such as obsessive-compulsive tendencies, tantrums, perseveration, insistence on sameness, and rigidity), and distinctive facial features.

Joint Modeling of Blood Pressure Measurements and Survival Time to Cardiovascular Disease Complication among Hypertension Patients Follow-up at DebreTabor Hospital, Ethiopia.

Introduction: Hypertension is also referred to as a silent killer and a leading factor for cardiovascular disease complication in the world today. This study aimed to identify the factors that affect longitudinal outcomes and survival time for cardiovascular disease complications among patients with hypertension.

Methods: A retrospective cohort study was conducted among a randomly selected sample of 178 outpatients with hypertension at the Debre Tabor Specialized Hospital between September 2017 and December 2019.

Adoption and impact of improved teff varieties adoption on food security: Micro level evidence from North Eastern Amhara Regional state, Ethiopia.

This study investigates the adoption and impact of improved teff varieties (ITVs) on food security in North Eastern Amhara Region, Ethiopia. The result of binary probit model shows that the adoption decision of improved teff varieties is determined by total family size measured in adult equivalent, off-farm income, number of traders known by farmers, variety information from development agents and research center affects positively and distance of farmer's residence from kebele office of agriculture negatively Endogenous switching regression (ESR)model was employed to evaluate the impacts of adoption of improved teff varieties on food security. The output from ESR asserted that had the adopter households decided not to adopt, their average daily calorie intake and annual food consumption expenditure per adult equivalent would have decreased by 417.

Malaria surveillance, outbreak investigation, response and its determinant factors in Waghemra Zone, Northeast Ethiopia: unmatched case-control study.

Malaria is a major global public health concern, with around half of the world's population at risk of infection. It is one of the most common epidemic-prone diseases, resulting in on-going epidemics and significant public health problems. On September 12, 2022, Waghemra Zone malaria monitoring data revealed that the district was suffering an unusually high number of malaria cases.

Posterior Mediastinal Hydatid Cyst with Spine and Chest Wall Involvement.

Hydatid cyst, which is caused by Echinococcus larvae, is a worldwide zoonotic disease which can affect virtually any organ in the body. Although the liver and lungs are the most commonly affected, it can occur in other parts of the body. Mediastinal hydatid cysts are incredibly rare, but imaging is crucial to diagnose and determine the extent of involvement and complications.

Timely initiation of first antenatal care visit and associated factors among pregnant women in the Amhara Region, North-west Ethiopia: a comparative cross-sectional study.

Introduction: timely initiation of the first antenatal care visit is still a major public health problem in Ethiopia, especially in Amhara Region. This study assessed the prevalence of timely initiation of first ANC visit and its associated factors among pregnant women in transformed and non-transformed districts, Awi zone, Amhara Region, North-west Ethiopia.

Methods: a community-based comparative cross-sectional study was conducted from November-December 2020, among 748 women.

Neurogenic pulmonary edema following Endoscopic third Ventriculostomy in patient with Hydrocephalous; case report.

Introduction And Importance: Neurogenic pulmonary edema (NPE) post endoscopic third ventriculostomy (ETV) is rare but fatal. Acute central brain injury complications are the most frequent cause.in this case uncommonly occur post ETV procedure.

Health system readiness to manage maternal death data and avail evidence for decision-making through the Maternal Death Surveillance System in Ethiopia, 2020.

Background: Maternal mortality remains a major health problem in Ethiopia. To generate contextual evidence on the burden and distribution of existing causes and contributing factors for programmatic and individual-level decision-making, the Maternal Death Surveillance and Response System was introduced in 2013. This assessment describes the Ethiopian health system's readiness to avail evidence for decision-making through the MDSR system.

High incidence rate of postoperative sore throat in intubated children at Northwest Amhara Comprehensive Specialized Hospitals, Ethiopia. A multicenter study.

Background: Postoperative sore throat is the most frequent complication in pediatric patients after general anesthesia. This study aimed to investigate the incidence of postoperative sore throat in patients undergoing general anesthesia with tracheal intubation or laryngeal mask airway.

Methods: A hospital-based multicenter prospective observational cohort study was conducted.

The prevalence of intestinal parasites, undernutrition and their associated risk factors among school-age children in Sekota Town, Northeast Ethiopia: A community-based cross-sectional study.

Background And Aims: In developing countries, intestinal parasitic infections and malnutrition are among the most serious health issues affecting school-aged children. They have synergetic consequences. This study aimed to determine the prevalence of intestinal parasites, undernutrition, and their associated risk factors among school-age children.

COVID-19 Stress and Teachers Well-Being: The Mediating Role of Sense of Coherence and Resilience.

The outbreak of the COVID-19 pandemic has impacted many professions with short-, medium-, and long-term consequences. Hence, this study examined the mediating role of sense of coherence (SOC) and resilience in the relation to COVID-19 stress and teachers' well-being (TWB). It recruited 836 teachers from Ethiopia's higher-education institutions, of which 630 (75.

The magnitude of mortality and its determinants in Ethiopian adult intensive care units: A systematic review and meta-analysis.

Introduction: Despite mortality in intensive care units being a global burden, it is higher in low-resource countries, including Ethiopia. A sufficient number of evidence is not yet established regarding mortality in the intensive care unit and its determinants. This study intended to determine the prevalence of ICU mortality and its determinants in Ethiopia.

Maternal satisfaction and associated factors towards institutional delivery service at public hospitals in the Somali region, Eastern Ethiopia.

Background: Client satisfaction reflects the gap between the expected service and the experience of the service, from the client's point of view. Maternal satisfaction with delivery services affects the selection of birthplaces and helps to identify gaps between actual health care and desired health care outcomes. There is a dearth of evidence on the factors of client satisfaction towards delivery services in the Somali region.