Use of Hair as Matrix for Trace Elements Biomonitoring in Cattle and Roe Deer Sharing Pastures in Northern Italy.

Intensive cattle breeding's environmental challenges are prompting shifts to extensive, pasture-based systems, influencing nutrient and pollutant uptake. PTEs are essential and non-essential elements, regularly found in the environment and organisms, and in which unbalances lead to health issues. Hair analysis, a non-invasive method, provides retrospective PTE exposure evaluation.

Enhancing chemotherapeutic efficacy: Niosome-encapsulated Dox-Cis with MUC-1 aptamer.

Background: Cancer remains a formidable global health challenge, currently affecting nearly 20 million individuals worldwide. Due to the absence of universally effective treatments, ongoing research explores diverse strategies to combat this disease. Recent efforts have concentrated on developing combined drug regimens and targeted therapeutic approaches.

Conservation of more evolutionary unique amphibian communities in Türkiye: The role of protected areas.

The alarming decline of amphibians, sometimes marked by sudden extinctions, underlines the urgent need for increased conservation efforts. Conservationists recognize that more action, particularly the setting of national targets, is needed to ensure the future persistence and recovery of species and habitats. Protecting habitats that harbor evolutionarily diverse species preserves divergent genetic information within ecosystems.

A novel radial basis neural network for the Zika virus spreading model.

The motive of current investigations is to design a novel radial basis neural network stochastic structure to present the numerical representations of the Zika virus spreading model (ZVSM). The mathematical ZVSM is categorized into humans and vectors based on the susceptible S(q), exposed E(q), infected I(q) and recovered R(q), i.e.

Enhanced photocatalytic property of Cu doped CeZrO toward photodegradation of methylene blue under visible light.

Widespread ecosystem degradation from noxious substances like industrial waste, toxic dyes, pesticides, and herbicides poses serious environmental risks. For remediation of these hazardous problems, present study introduces an innovative Cu-doped Ce₂Zr₂O₇ nano-photocatalyst, fabricated via a simple, eco-friendly hydrothermal method, designed to degrade toxic textile dye methylene blue. Harnessing Cu doping for pyrochlore CeZrO, structure engineering carried out through a hydrothermal synthesis method to achieve superior photocatalytic performance, addressing limitations of rapid charge carrier recombination in existing photocatalysts.

The effect of constant electric field on the crack growth process of aluminum nanosheet using molecular dynamics simulation.

Aluminum nanosheets are a form of Al nanoparticle that have been recently manufactured on an industrial scale and have a variety of uses. Al nanoparticles are extensively used in a variety of sectors, including aerospace, construction, medical, chemistry, and marine industries. Crack propagation in various constructions must be investigated thoroughly for structural design purposes.

The effect of different subtalar joint pronation amounts on postural stability, function and lower extremity alignment in healthy individuals.

Introduction: The prone foot posture has a negative effect on postural stability, function, and knee valgus, but to our knowledge, the contribution of the degree of pronation has not been examined.

Methods: 39 participants aged 18-40, with Foot Posture Index (FPI) scores between 6-12 and without any pain complaints were included. Participants with 6-9 points were included in the pronation group (PG) (n = 19), and participants with 10-12 points were included in the hyperpronation group (HPG) (n = 20).

The impact of response type on affordance and spatial compatibility effects in human and object interactions.

Everyday social interactions or goal-directed actions towards objects activate action plans appropriate to their affordances. The spatial compatibility of a stimulus and a response might interfere with the activation of these action plans. In the present study, we examined how framing of interactions affects the interplay between affordance and spatial compatibility effects towards humans and objects in two separate experiments.

A machine learning approach to determine the risk factors for fall in multiple sclerosis.

Background: Falls in multiple sclerosis can result in numerous problems, including injuries and functional loss. Therefore, determining the factors contributing to falls in people with Multiple Sclerosis (PwMS) is crucial. This study aims to investigate the contributing factors to falls in multiple sclerosis using a machine learning approach.

Conjunctival Histopathological Changes and Clinical Tear Film in Children with Atopic Dermatitis.

Purpose: Evaluation of changes in the ocular surfaces in children with a diagnosis of atopic dermatitis (AD).

Methods: Thirty-six children with a diagnosis of AD (Eye-AD group) and 40 healthy subjects (Eye-HS group) were enrolled in this prospective case-control study. Tear film break-up time (T-BUT), Schirmer tear test (STT), conjunctival impression cytology (CIC), tear meniscus height (TMH), tear meniscus area (TMA), and ocular surface disease index (OSDI) were measured.

Testing the role of unstimulated in vitro maturation for potential development of immature oocytes in women with oocyte maturation abnormalities.

Objective: The aim of this study was to investigate the developmental potential of immature oocytes and evaluate whether unstimulated in vitro maturation (IVM) could serve as a treatment option for women with oocyte maturation abnormalities (OMAs).

Material And Methods: This cohort study was conducted between September 2019 and December 2022, and included women who underwent unstimulated, non-human chorionic gonadotropin (hCG) priming IVM. Oocytes were incubated with IVM medium for 26-48 hours and evaluated to compare their maturation profiles with the immature oocytes retrieved from the same patients in their previous in vitro fertilization cycles.

Liver Fibrosis: From Basic Science towards Clinical Progress, Focusing on the Central Role of Hepatic Stellate Cells.

The burden of chronic liver disease is globally increasing at an alarming rate. Chronic liver injury leads to liver inflammation and fibrosis (LF) as critical determinants of long-term outcomes such as cirrhosis, liver cancer, and mortality. LF is a wound-healing process characterized by excessive deposition of extracellular matrix (ECM) proteins due to the activation of hepatic stellate cells (HSCs).

Describing an old trick in posterior thoracal and lumbar ımplant removal surgery: follow-up results for at least 10 years.

Study Design: Retrospective case series.

Objectives: We aimed to describe with a novel surgical approach for the removal of posterior thoracolumbar implant in patients with symptomatic failure of the implant and present our preliminary results with this method.

Methods: This retrospective, single-center study was performed in the neurosurgery department of a university hospital.

Health information systems with technology acceptance model approach: A systematic review.

In the rapidly evolving landscape of information technologies, individuals and organizations must adapt to the digital age. Given the diversity in users' knowledge and experience with technology, their acceptance levels also vary. Over the past 30 years, various theoretical models have been introduced to provide a framework for understanding user acceptance of technology.

A novel algorithm for the virtual screening of extensive small molecule libraries against ERCC1/XPF protein-protein interaction for the identification of resistance-bypassing potential anticancer molecules.

Background And Aim: Cancer cell's innate chemotherapeutic resistance continues to be an obstacle in molecular oncology. This theory is firmly tied to the cancer cells' integral DNA repair mechanisms continuously neutralizing the effects of chemotherapy. Amidst these mechanisms, the nuclear excision repair pathway is crucial in renovating DNA lesions prompted by agents like Cisplatin.

LUNGBANK: a novel biorepository strategy tailored for comprehensive multiomics analysis and P-medicine applications in lung cancer.

Background/aim: LUNGBANK was established as part of Project LUNGMARK, pioneering a biorepository dedicated exclusively to lung cancer research. It employs cutting-edge technologies to streamline the handling of biospecimens, ensuring the acquisition of high-quality samples. This infrastructure is fortified with robust data management capabilities, enabling seamless integration of diverse datasets.

Influence of endodontic access cavity design on mechanical properties of a first mandibular premolar tooth: a finite element analysis study.

Objectives: This study aimed to investigate the influence of access cavity designs on the mechanical properties of a single-rooted mandibular first premolar tooth under various static loads using a finite element analysis.

Materials And Methods: 3-dimensional FEA designs were modeled according to the access cavity designs: an intact tooth (control), traditional access cavity (TEC-I), traditional access cavity with Class-II mesio-occlusal cavity design (TEC-II), conservative access cavity (CEC), ninja access cavity (NEC), caries-driven access cavity (Cd-EC), buccal access cavity (BEC) and bucco-occlusal access cavity (BOEC). After the simulated access cavity preparations, root canal treatment was simulated and three different static loads which mimicked oblique and vertical mastication forces were applied to the models.

Outcomes after 4 years' experience with low suction drains. Would it be safe to go drainless or low suction?

Background: The principles of chest drainage have not changed significantly since 1875 when Bülau introduced the idea of underwater drainage tube which became a trademark of thoracic surgery. We performed a prospective, randomized trial comparing omitting pleural drain (drainless group) versus drainage with small low suction drain (drainage group) strategies of thoracic surgery when the visceral pleura remains intact. Aiming to investigate whether these approaches represent safe treatment options.

Inflammation Burden and Atrial Fibrillation Burden: A Bidirectional Relationship.

Background: Atrial fibrillation (AF) burden is defined as the proportion of time the patient remains in AF over a given period of time; thus, it is theoretically highest in permanent AF and lowest in paroxysmal AF. Inflammation is associated with the initiation and maintenance of AF. However, the relationship between systemic immune-inflammation index (SII) and AF burden is unknown.

The effect of uric acid and albumin ratio in undergoing lower extremity endovascular interventions for peripheral arterial disease related contrast induced nephropathy.

Background: Among patients undergoing percutaneous vascular intervention, contrast-induced nephropathy (CIN) is associated with increased morbidity and mortality. Serum uric acid/albumin ratio (UAR) has emerged as a new marker associated with poor cardiovascular outcomes. We aimed to evaluate the relationship between UAR and CIN occurrence in patients treated for peripheral artery disease.