750 results match your criteria: "Bacillary Angiomatosis"
A 34-year-old male patient presented with a clinical picture of multilocular subcutaneous skin nodules in addition to marked lymphadenopathy and general physical deterioration. A comprehensive diagnostic workup including serology, skin biopsy and imaging studies led to the initial diagnosis of human immunodeficiency virus (HIV) infection in AIDS stage with rare multilocular subcutaneous bacillary angiomatosis (BA) caused by Bartonella henselae. BA describes a process of neovascularisation of the skin or of internal organs (particularly the liver and spleen) and was first described in HIV-positive patients by Stoler et al.
View Article and Find Full Text PDFDifferential vasoproliferative traits of strains associated with autotransporter BafA variants.
Microbiol Spectr
November 2024
Laboratory of Bacterial Zoonoses, International Research Center for Infectious Diseases, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan.
Article Synopsis
Article Synopsis
- Bartonella quintana infection can cause serious health issues like bacillary angiomatosis and culture-negative endocarditis, mainly affecting individuals who are homeless.
- In a study conducted in New York City between January 2020 and November 2023, five cases of left-sided, culture-negative endocarditis were identified in unsheltered homeless persons using molecular methods.
- Most patients had serious complications and a history of body louse exposure, highlighting the need for clinicians to consider housing status and potential lice infestation when diagnosing and treating suspected cases.
Multifocal cutaneous neoplastic vascular proliferations in a rainbow boa (Epicrates cenchria) collection with boid inclusion body disease.
PLoS One
November 2024
Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.
Article Synopsis
- - The study details rare cases of skin tumors in Brazilian rainbow boas, identifying conditions similar to hemangioma and hemangioendothelioma, and examining possible links to boid inclusion body disease (BIBD).
- - Thirteen snakes exhibited the skin lesions, with a mix of introduced animals and those bred in-house; lesions emerged over eight years, but no new cases were recorded in the last five years.
- - Diagnostic tests confirmed BIBD in five snakes, alongside the presence of reptarenavirus in the tumors, suggesting a potential connection between the virus and the observed neoplastic conditions, warranting further research.
Donor-derived bartonellosis in solid organ transplant recipients from unhoused donors in Alberta.
Am J Transplant
September 2024
Division of Infectious Diseases, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
Article Synopsis
- - A study in Alberta from 2022-2023 highlighted cases of Bartonella quintana infection transmitted through solid organ transplants (SOT) from unhoused deceased donors (UDDs), with a notable attack rate of 12.5% among recipients.
- - Out of 32 organ recipients from seropositive donors, 6 developed skin-related symptoms of bartonellosis, with the majority showing positive serology results for Bartonella.
- - This incident underscores the risk of unexpected infections from donors with a history of substance use, emphasizing the need for vigilance among clinicians regarding potential transmission through organ transplants.
Donor-Derived Infection in Solid Organ Transplantation: An Emerging Public Health Issue With Diagnostic Challenges.
Open Forum Infect Dis
August 2024
Department of Infectious Disease, Faculty of Medicine and Dentistry Medicine, University of Alberta, Edmonton, Alberta, Canada.
Article Synopsis
- A louse-borne bacterium is highlighted as a neglected cause of serious infections, particularly affecting impoverished individuals and can lead to conditions like bacteremia and infective endocarditis.
- In October 2023, Health Canada reported an outbreak of donor-derived infections linked to three deceased homeless donors in Alberta, Canada, adding to similar cases in the U.S.
- The article emphasizes the need for better screening of organ donors and monitoring of transplant recipients, discussing both epidemiological strategies and the limitations of current diagnostic tests in the transplant setting.
Bacillary Angiomatosis in a Patient With HIV and Disseminated Mycobacterium avium Complex Infection.
Cureus
June 2024
Dermatology, Michael E. DeBakey Veterans Affairs Medical Center, Baylor College of Medicine, Houston, USA.
Article Synopsis
- The text discusses a genus of bacteria that cause infections in mammals, primarily affecting red blood cells and blood vessels.
- In humans, infections can lead to different diseases based on immune system status, such as cat-scratch disease in healthy individuals and bacillary angiomatosis in those with weakened immunity.
- The case presented involves a 32-year-old woman with HIV who has a rare infection, highlighting the need for healthcare professionals to recognize uncommon infections in immunocompromised patients for timely diagnosis and treatment.
A systematic review on antibiotic therapy of cutaneous bacillary angiomatosis not related to major immunocompromising conditions: from pathogenesis to treatment.
BMC Infect Dis
April 2024
Dipartimento di Scienze di Laboratorio e Infettivologiche, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Article Synopsis
- Cutaneous bacillary angiomatosis (cBA) is a rare vascular disorder primarily affecting immunocompromised individuals, such as those living with HIV or on immunosuppressive medication, and may be underdiagnosed in healthier patients.
- A literature search identified 22 cases of cBA in patients without major immunocompromising conditions, revealing that those with a single lesion often required shorter antibiotic treatment than those with multiple lesions.
- Personalized treatment plans incorporating molecular tests and considering disease severity may improve outcomes for patients with cBA, as current evidence-based treatment guidelines are lacking.
Is sp. infection relevant in hematological malignancies in HIV-negative patients? A literature review.
Leuk Res Rep
December 2023
Department of Clinical Medicine, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, SP, Brazil.
Article Synopsis
- Bartonelloses are diseases caused by Bartonella bacteria, transmitted to humans through blood-sucking insects, leading to conditions like bacillary angiomatosis and cat scratch disease.
- A review of cases involving bartonelloses and blood cancers in HIV-negative patients identified 15 relevant cases, highlighting various symptoms such as chronic fever and lymphadenopathy.
- Most patients responded well to antibiotic treatment, but clinicians need to be vigilant for Bartonella infections, especially in immunocompromised individuals.
An autochthonous case of cutaneous bacillary angiomatosis not related to major immunosuppression: An emerging or overlooked disease?
Int J Infect Dis
January 2024
Infectious and Tropical Diseases Unit, "Renato Dulbecco" University Hospital, Catanzaro, Italy. Electronic address:
Article Synopsis
- Cutaneous bacillary angiomatosis (cBA) is a rare vascular disorder primarily linked to Bartonella infections, typically seen in individuals with HIV, leading to potential underdiagnosis in those without severe immunosuppression.
- A case of a 67-year-old Italian man with no major immunocompromising conditions illustrates the challenges of diagnosing cBA, as he experienced a lengthy symptom onset before proper identification.
- Successful treatment involved a combination of antibiotics based on molecular testing, highlighting the need for clinicians to consider cBA in patients with milder immune issues and the importance of personalized treatment strategies due to the lack of established guidelines.
Point-of-care ultrasound for tuberculosis and HIV-revisiting the focused assessment with sonography for HIV-associated tuberculosis (FASH) protocol and its differential diagnoses.
Clin Microbiol Infect
March 2024
Lighthouse Clinic Trust, Lilongwe, Malawi; International Training and Education Center for Health, University of Washington, Seattle, WA, USA.
Article Synopsis
- The FASH protocol has been used for over a decade to help diagnose extra-pulmonary tuberculosis in HIV-infected patients, but interpreting its results can be difficult due to overlapping features with other diseases.
- A review analyzed ten studies on the FASH protocol's accuracy, revealing sensitivity and specificity rates for enlarged lymph nodes and spleen lesions that suggest it can effectively indicate tuberculosis but also requires careful consideration of other potential diagnoses.
- The review recommends basic ultrasound training in the FASH protocol and ultrasound-guided diagnostic sampling to improve diagnosis, acknowledging that current evidence is limited and more research is needed.
Cat Scratch Disease: An Unusual Case of Right Inguinal Lymphadenitis Due to Bartonella henselae.
Cureus
August 2023
Infectious Diseases, Augusta University Medical College of Georgia, Augusta, USA.
Article Synopsis
- - Cat scratch disease (CSD) is a bacterial infection mainly linked to young cats and manifests as swollen lymph nodes, particularly in children and young adults; while most immunocompetent individuals recover fully, immunocompromised patients can face serious health issues.
- - Transmission typically occurs through scratches or bites from cats, but there are rare cases (1%) where patients develop CSD without any animal interaction.
- - A case study involved a healthy 29-year-old man with severe groin pain who, despite no visible scratches, was diagnosed with CSD after imaging and a lymph node biopsy; he was treated effectively, highlighting the need for careful patient evaluation and timely treatment.
A Comprehensive Review on HIV-Associated Dermatologic Manifestations: From Epidemiology to Clinical Management.
Int J Microbiol
July 2023
Autoimmune Bullous Diseases Research Center, Razi Hospital, Tehran University of Medical Sciences, Tehran 1199663911, Iran.
Article Synopsis
- Dermatological disorders are common in HIV/AIDS patients, featuring a range of skin and mucous membrane symptoms.
- The review categorizes various skin issues caused by HIV, including specific skin conditions, opportunistic infections, and skin cancers.
- The aim is to help clinicians better recognize and manage the diverse cutaneous manifestations associated with HIV/AIDS.
Angioma-like eruption in an elderly female.
J Dtsch Dermatol Ges
August 2023
Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Case Report: Role of Point-of-Care Ultrasound in the Diagnosis of Bacillary Angiomatosis.
Am J Trop Med Hyg
July 2023
Lighthouse Clinic Trust, Lilongwe, Malawi.
Article Synopsis
- * Portable ultrasound devices and specific protocols like FASH for HIV-related TB are helping improve diagnostic accuracy in these settings.
- * A case study of bacillary angiomatosis in an advanced HIV patient highlights the effectiveness of combining clinical skills with ultrasound and biopsy for accurate diagnosis and treatment.
Bacillary Angiomatosis Mimicking Pyogenic Granuloma.
Cureus
March 2023
Oral Biology, Saveetha Dental College and Hospitals, Chennai, IND.
Article Synopsis
- - Bacillary angiomatosis (BA) is a disease that causes the growth of abnormal blood vessels, primarily affecting immunocompromised individuals with symptoms like nodules or papules.
- - Oral lesions are uncommon, while skin lesions are more frequent, and histopathology is essential for accurate diagnosis.
- - Treatment typically involves antibiotics from the macrolide class, such as erythromycin, clarithromycin, or doxycycline.
Invasive bacillary angiomatosis in a kidney transplant recipient: A challenging case on belatacept immunosuppression.
Int J Infect Dis
August 2023
Department of Nephrology, Dialysis, and Transplantation, Bicêtre Hospital, AP-HP, Le Kremlin-Bicêtre, France; Paris Saclay University, Gif-sur-Yvette, France.
Article Synopsis
- * A case study of a 75-year-old female kidney transplant recipient showed symptoms including fever, chills, and weight loss, but initial tests for the disease returned negative results.
- * Ultimately, despite negative blood cultures and serological tests, a biopsy of a celiac lymph node confirmed bacillary angiomatosis, highlighting the need for careful evaluation and high clinical suspicion when diagnosing in immunocompromised patients.
Bacillary Angiomatosis Involving Tongue in a Patient with Myelofibrosis.
Indian J Dermatol
January 2022
Department of Dermatology, Zoram Medical College, Mizoram, India E-mail:
The autotransporter BafA contributes to the proangiogenic potential of Bartonella elizabethae.
Microbiol Immunol
May 2023
Department of Microbiology, Fujita Health University School of Medicine, Toyoake, Japan.
Article Synopsis
- Bartonella elizabethae is a rat-borne bacterium linked to human diseases like endocarditis and neuroretinitis, and it may also trigger bacillary angiomatosis (BA), which involves unusual blood vessel growth.
- Recent research proposed that B. elizabethae could contain a gene related to the proangiogenic protein BafA, similar to those found in other Bartonella species known to cause BA.
- The study found that the BafA from B. elizabethae promotes endothelial cell proliferation and capillary formation, suggesting that this bacterium might play a significant role in enhancing blood vessel growth in humans.
Cutaneous nodules and hepatosplenic lesions caused by bacillary angiomatosis in a patient with AIDS.
BMJ Case Rep
February 2023
Departments of Internal Medicine & Dermatology, UT Southwestern, Dallas, Texas, USA
Bacillary Angiomatosis in an Immunocompetent Patient: An Unusual Occurrence.
Indian Dermatol Online J
June 2022
Department of Pathology, University College of Medical Sciences and GTB Hospital (University of Delhi), New Delhi, India.
Cutaneous lesions of bacillary angiomatosis.
Rev Soc Bras Med Trop
August 2022
Hospital Melaka, Pathology Department, Melaka, Malaysia.
Detection of subsp. in an HIV patient using metagenomic Next-Generation Sequencing.
Emerg Microbes Infect
December 2022
Department of Clinical Laboratory, Infection Hospital Area of the First Affiliated Hospital of University of Science and Technology of China, Hefei, People's Republic of China.
Article Synopsis
- Bartonella species are aerobic bacteria spread by blood-sucking insects and can cause various diseases like cat scratch disease and Carrion's disease.
- A case study details a 31-year-old male with AIDS who experienced persistent fever and knee ulcerations, leading to the identification of a Bartonella infection through advanced sequencing despite negative blood cultures.
- After treatment with antibiotics, the patient's ulcers improved, but he ultimately succumbed to respiratory failure, highlighting the severe impact of Bartonella in immunocompromised individuals.
Hundreds of vasculoproliferative skin lesions in a paediatric renal transplant recipient.
Clin Exp Dermatol
September 2022
Departments of Dermatology, Hospital Universitario Cruces, Bizkaia, Spain.
Article Synopsis
- - Bacillary angiomatosis is an infectious disease characterized by abnormal blood vessel growth, primarily affecting individuals with HIV and occasionally organ transplant recipients.
- - The article discusses a notable case of bacillary angiomatosis caused by Bartonella quintana in a young patient who received a kidney transplant, showing skin, lymph node, and bone involvement.
- - The patient responded very well to treatment with doxycycline, indicating its effectiveness against this condition.