2 results match your criteria: "Bach Institute of Biochemistry Research Center of Biotechnology[Affiliation]"
Infection: Control and Treatment.
Microorganisms
April 2023
Bach Institute of Biochemistry Research Center of Biotechnology, Russian Academy of Sciences, 119071 Moscow, Russia.
Tuberculosis (TB) is the second leading infectious killer after COVID-19, causing 10 million new cases and claiming the lives of more than 1 [...
View Article and Find Full Text PDFMechanism of curaxin-dependent nucleosome unfolding by FACT.
Front Mol Biosci
November 2022
Biology Faculty Lomonosov Moscow State University, Moscow, Russia.
Human FACT (FACT) is a multifunctional histone chaperone involved in transcription, replication and DNA repair. Curaxins are anticancer compounds that induce FACT-dependent nucleosome unfolding and trapping of FACT in the chromatin of cancer cells (c-trapping) through an unknown molecular mechanism. Here, we analyzed the effects of curaxin CBL0137 on nucleosome unfolding by FACT using spFRET and electron microscopy.
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