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Structure-function relationship of PE11 esterase of Mycobacterium tuberculosis with respect to its role in virulence.
Biochem Biophys Res Commun
December 2024
Laboratory of Molecular Cell Biology, BRIC-Center for DNA Fingerprinting and Diagnostics (CDFD), Hyderabad, 500039, Telangana, India. Electronic address:
The lipolytic enzymes of Mycobacterium tuberculosis play a critical role in immunomodulation and virulence. Among these proteins, PE11 which also belongs to the PE/PPE family, is the smallest (∼10.8 kDa) and play a significant role in cell wall remodelling and virulence.
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