2 results match your criteria: "BKC Ritsumeikan University[Affiliation]"
Ambroxol-enhanced ciliary beating via voltage-gated Ca channels in mouse airway ciliated cells.
Eur J Pharmacol
February 2023
Research Laboratory for Epithelial Physiology, Research Organization of Science and Technology, BKC Ritsumeikan University, Kusatsu, 525-8577, Japan; Medical Research Institute, Kyoto Industrial Health Association, Kyoto, 604-8472, Japan. Electronic address:
Ambroxol (ABX) facilitates the mucociliary clearance (MC) by enhancing ciliary beating in airways. In this study, we focused on airway ciliary beating enhanced by ABX. However, little is known about the ABX-stimulated Ca signalling activating airway ciliary beating.
View Article and Find Full Text PDFEnhancement of airway ciliary beating mediated via voltage-gated Ca channels/α7-nicotinic receptors in mice.
Pflugers Arch
October 2022
Research Laboratory for Epithelial Physiology, Research Organization of Science and Technology, BKC Ritsumeikan University, Kusatsu, 525-8577, Japan.
Acetylcholine (ACh), which activates muscarinic ACh receptors (mAChRs) and nicotinic ACh receptors (nAChRs), enhances airway ciliary beating by increasing the intracellular Ca concentration ([Ca]). The mechanisms enhancing airway ciliary beating by nAChRs have remained largely unknown, although those by mAChRs are well understood. In this study, we focused on the effects of α7-nAChRs and voltage-gated Ca channels (Cas) on the airway ciliary beating.
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