173 results match your criteria: "B.P. Konstantinov Petersburg Nuclear Physics Institute[Affiliation]"
Eur Phys J C Part Fields
May 2016
CERN, Geneva, Switzerland.
This paper presents a new method of reconstructing the individual charged and neutral hadrons in tau decays with the ATLAS detector. The reconstructed hadrons are used to classify the decay mode and to calculate the visible four-momentum of reconstructed tau candidates, significantly improving the resolution with respect to the calibration in the existing tau reconstruction. The performance of the reconstruction algorithm is optimised and evaluated using simulation and validated using samples of [Formula: see text] and [Formula: see text]+jets events selected from proton-proton collisions at a centre-of-mass energy [Formula: see text], corresponding to an integrated luminosity of 5 [Formula: see text].
View Article and Find Full Text PDFEur Phys J C Part Fields
May 2016
CERN, Geneva, Switzerland.
This article documents the performance of the ATLAS muon identification and reconstruction using the LHC dataset recorded at [Formula: see text] TeV in 2015. Using a large sample of [Formula: see text] and [Formula: see text] decays from 3.2 fb[Formula: see text] of collision data, measurements of the reconstruction efficiency, as well as of the momentum scale and resolution, are presented and compared to Monte Carlo simulations.
View Article and Find Full Text PDFEur Phys J C Part Fields
May 2016
CERN, Geneva, Switzerland.
Distributions of transverse momentum [Formula: see text] and the related angular variable [Formula: see text] of Drell–Yan lepton pairs are measured in 20.3 fb[Formula: see text] of proton–proton collisions at [Formula: see text] TeV with the ATLAS detector at the LHC. Measurements in electron-pair and muon-pair final states are corrected for detector effects and combined.
View Article and Find Full Text PDFEur Phys J C Part Fields
May 2016
CERN, Geneva, Switzerland.
The production rates of prompt and non-prompt [Formula: see text] and [Formula: see text] mesons in their dimuon decay modes are measured using 2.1 and 11.4 fb[Formula: see text] of data collected with the ATLAS experiment at the Large Hadron Collider, in proton-proton collisions at [Formula: see text] and 8 respectively.
View Article and Find Full Text PDFEur Phys J C Part Fields
May 2016
CERN, Geneva, Switzerland.
A search for strongly produced supersymmetric particles is conducted using signatures involving multiple energetic jets and either two isolated leptons ( or [Formula: see text]) with the same electric charge or at least three isolated leptons. The search also utilises -tagged jets, missing transverse momentum and other observables to extend its sensitivity. The analysis uses a data sample of proton-proton collisions at [Formula: see text] TeV recorded with the ATLAS detector at the Large Hadron Collider in 2015 corresponding to a total integrated luminosity of 3.
View Article and Find Full Text PDFEur Phys J C Part Fields
April 2016
CERN, Geneva, Switzerland.
Eur Phys J C Part Fields
April 2016
CERN, Geneva, Switzerland.
This article presents the sensitivity of the ATLAS experiment to the lepton-flavour-violating decays of [Formula: see text]. A method utilising the production of [Formula: see text] leptons via [Formula: see text] decays is used. This method is applied to the sample of 20.
View Article and Find Full Text PDFEur Phys J C Part Fields
April 2016
CERN, Geneva, Switzerland.
Eur Phys J C Part Fields
April 2016
CERN, Geneva, Switzerland.
Philos Trans A Math Phys Eng Sci
January 2016
Division of Molecular and Radiation Biophysics, B.P. Konstantinov Petersburg Nuclear Physics Institute, National Research Centre 'Kurchatov Institute', 188300 Gatchina, Russia Department of Physical Methods and Devices for Quality Control, Institute of Physics and Technology, Ural Federal University, 620002 Ekaterinburg, Russia
This article examines the question of the possible existence of microbial life inhabiting the subglacial Lake Vostok buried beneath a 4 km thick Antarctic ice sheet. It represents the results of analysis of the only available frozen lake water samples obtained upon the first lake entry and subsequent re-coring the water frozen within the borehole. For comparison, results obtained by earlier molecular microbiological studies of accretion ice are included in this study, with the focus on thermophiles and an unknown bacterial phylotype.
View Article and Find Full Text PDFNanomedicine
April 2016
Technische Universität München, Klinikum rechts der Isar, Radiation Oncology, Munich, Germany.
Unlabelled: Superparamagnetic iron-oxide based contrast agents can provide important diagnostic information regarding the assessment of cardiac inflammatory diseases. The aim of the study was to analyze whether nanoparticles conjugated to recombinant 70-kDa heat shock protein (Hsp70-SPION) can be applied for the detection of acute myocardium infarct by MRI. Cellular experiments demonstrated increased CD40-mediated uptake of Hsp70-SPIONs in comparison to non-conjugated SPIONs.
View Article and Find Full Text PDFBiochimie
February 2016
Institute of Cytology, RAS, Tikhoretski Ave. 4, Saint-Petersburg, RF, 194064, Russia.
Atomic force microscopy (AFM) was used to study mononucleosomes reconstituted from a DNA duplex of 353 bp containing the strong 601 octamer positioning sequence, together with recombinant human core histone octamers. Three parameters were measured: 1) the length of DNA wrapped around the core histones; 2) the number of superhelical turns, calculated from the total angle through which the DNA is bent, and 3) the volume of the DNA-histone core. This approach allowed us to define in detail the structural diversity of nucleosomes caused by disassembly of the octasome to form subnucleosomal structures containing hexasomes, tetrasomes and disomes.
View Article and Find Full Text PDFEur Phys J C Part Fields
September 2015
CERN, Geneva, Switzerland.
Many extensions of the Standard Model predict the existence of charged heavy long-lived particles, such as -hadrons or charginos. These particles, if produced at the Large Hadron Collider, should be moving non-relativistically and are therefore identifiable through the measurement of an anomalously large specific energy loss in the ATLAS pixel detector. Measuring heavy long-lived particles through their track parameters in the vicinity of the interaction vertex provides sensitivity to metastable particles with lifetimes from 0.
View Article and Find Full Text PDFBiomed Khim
March 2016
Federal Almazov North-West Medical Research Centre, St. Petersburg, Russia; Mechnikov North-Western State Medical University, St. Petersburg, Russia.
Cerebrovascular disease is a main cause of mortality and one of the big medical problems. After the vascular wall's damage the endothelial cells secrete the von Willebrand factor which then connects with its platelet's receptor GP Ib-V-IX. There are two polymorphisms Thr145Met and T(-5)C of the GP Iba gene associated with arterial thrombosis development.
View Article and Find Full Text PDFVirtual and experimental 2DE coupled with ESI LC-MS/MS was introduced to obtain better representation of the information about human proteome. The proteins from HEPG2 cells and human blood plasma were run by 2DE. After staining and protein spot identification by MALDI-TOF MS, the protein maps were generated.
View Article and Find Full Text PDFPhys Rev Lett
September 2015
CERN, Geneva, Switzerland.
Results of a search for new phenomena in events with large missing transverse momentum and a Higgs boson decaying to two photons are reported. Data from proton-proton collisions at a center-of-mass energy of 8 TeV and corresponding to an integrated luminosity of 20.3 fb^{-1} have been collected with the ATLAS detector at the LHC.
View Article and Find Full Text PDFPhys Rev Lett
September 2015
Institut für Kernphysik, Universität zu Köln, 50937 Köln, Germany.
The preservation of the nuclear polarization of hydrogen atoms during the recombination to molecules was observed on different surface materials in the temperature range from 45 to 100 K and for magnetic fields up to 1 T. On a gold and a fused quartz surface, the expected molecular polarization of about 50% or lower of the atomic polarization was measured, while a surface layer of perfluoropolyether (Fomblin) shows a nearly complete preservation (at least 97%) of the atomic polarization during the recombination process. Further experiments have the possibility of storing polarized deuterium molecules and to use them in nuclear-fusion installations.
View Article and Find Full Text PDFEur Phys J C Part Fields
September 2015
CERN, Geneva, Switzerland.
A search for Higgs boson pair production [Formula: see text] is performed with 19.5 fb[Formula: see text] of proton-proton collision data at [Formula: see text] TeV, which were recorded by the ATLAS detector at the Large Hadron Collider in 2012. The decay products of each Higgs boson are reconstructed as a high-momentum [Formula: see text] system with either a pair of small-radius jets or a single large-radius jet, the latter exploiting jet substructure techniques and associated -tagged track-jets.
View Article and Find Full Text PDFFEBS J
December 2015
Department of Chemistry and Biotechnology, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Unlabelled: The ascomycete Geotrichum candidum is a versatile and efficient decay fungus that is involved, for example, in biodeterioration of compact discs; notably, the 3C strain was previously shown to degrade filter paper and cotton more efficiently than several industrial enzyme preparations. Glycoside hydrolase (GH) family 7 cellobiohydrolases (CBHs) are the primary constituents of industrial cellulase cocktails employed in biomass conversion, and feature tunnel-enclosed active sites that enable processive hydrolytic cleavage of cellulose chains. Understanding the structure-function relationships defining the activity and stability of GH7 CBHs is thus of keen interest.
View Article and Find Full Text PDFGenet Mol Res
August 2015
Molecular and Radiation Biophysics Division, National Research Centre "Kurchatov Institute" B.P. Konstantinov Petersburg Nuclear Physics Institute, Gatchina, Russia.
Amyloid precursor protein (APP) is a key player in Alzheimer's disease. The proteolytic cleavage of APP results in various short peptide fragments including the toxic amyloid-beta peptide, which is a main component of senile plaques. However, the functions of APP and its processed fragments are not yet well understood.
View Article and Find Full Text PDFEur Phys J C Part Fields
August 2015
CERN, Geneva, Switzerland.
A search for heavy long-lived multi-charged particles is performed using the ATLAS detector at the LHC. Data collected in 2012 at [Formula: see text] TeV from collisions corresponding to an integrated luminosity of 20.3 fb[Formula: see text]are examined.
View Article and Find Full Text PDFPhys Rev Lett
May 2015
University of Wisconsin, Madison, Wisconsin, USA.
A measurement of the Higgs boson mass is presented based on the combined data samples of the ATLAS and CMS experiments at the CERN LHC in the H→γγ and H→ZZ→4ℓ decay channels. The results are obtained from a simultaneous fit to the reconstructed invariant mass peaks in the two channels and for the two experiments. The measured masses from the individual channels and the two experiments are found to be consistent among themselves.
View Article and Find Full Text PDFCarbohydr Res
August 2015
National Research Center "Kurchatov Institute", B.P. Konstantinov Petersburg Nuclear Physics Institute, 188300, Gatchina, Orlova roscha, Russia; St. Petersburg State Polytechnical University, 29 Politekhnicheskaya st., 195251 St. Petersburg, Russia.
In the present work we suggest an efficient method, using the whole time course of the reaction, whereby parameters kcat, Km and product KI for the hydrolysis of a p-nitrophenyl glycoside by an exo-acting glycoside hydrolase can be estimated in a single experiment. Its applicability was demonstrated for three retaining exo-glycoside hydrolases, β-xylosidase from Aspergillus awamori, β-galactosidase from Penicillium sp. and α-galactosidase from Thermotoga maritima (TmGalA).
View Article and Find Full Text PDFProc Natl Acad Sci U S A
May 2015
York Structural Biology Laboratory, Department of Chemistry, and
The reduction of specific uridines to dihydrouridine is one of the most common modifications in tRNA. Increased levels of the dihydrouridine modification are associated with cancer. Dihydrouridine synthases (Dus) from different subfamilies selectively reduce distinct uridines, located at spatially unique positions of folded tRNA, into dihydrouridine.
View Article and Find Full Text PDFNature
April 2015
1] 3D Electron Cryomicroscopy Group, Max-Planck-Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany [2] Department of 3D Electron Cryomicroscopy, Institute of Microbiology and Genetics, Georg-August Universität, 37077 Göttingen, Germany.
Single particle electron cryomicroscopy (cryo-EM) has recently made significant progress in high-resolution structure determination of macromolecular complexes due to improvements in electron microscopic instrumentation and computational image analysis. However, cryo-EM structures can be highly non-uniform in local resolution and all structures available to date have been limited to resolutions above 3 Å. Here we present the cryo-EM structure of the 70S ribosome from Escherichia coli in complex with elongation factor Tu, aminoacyl-tRNA and the antibiotic kirromycin at 2.
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