Design, Synthesis and Evaluation of Antifungal Activity of Pyrazoleacetamide Derivatives.

Background: Fungal infections have posed a big challenge in the management of their treatment. Due to the resistance and toxicity of existing drug molecules in the light of pandemic infections, like COVID-19, there is an urgent need to find newer derivatives of active molecules, which can be effective in fungal infections.

Objective: In the present study, we aimed to design pyrazole derivatives using molecular modeling studies against target 1EA1 and synthesize 10 molecules of pyrazole derivatives using a multi-step synthesis approach.

Toxicity mechanism of Cu ion individually and in combination with Zn ion in characterizing the molecular changes of Staphylococcus aureus studied using FTIR coupled with chemometric analysis.

Copper and zinc have a high binding affinity with a Staphylococcus aureus bacterial community. This causes a change in the biomolecular composition of S. aureus.

Influence of microbial fuel cell with porous anode on voltage generation, chemical oxygen demand, chloride content and total dissolved solids.

Microbial fuel cells were developed using two different water sources: (1) unpolluted water (Kala Talao Lake) and (2) polluted water (Waldhuni River). The maximum output voltage provided by each source was compared, as was the cell voltage variation with anode porosity. The variation in power density of each cell with variation in anode porosity was also studied.

Qualitative HPTLC phytochemical profiling of Roxb. bark, leaves and seeds.

Roxb. (Family: Lecythidaceae is commonly called as Slow match tree and is an important medicinal plant. Its different parts viz.

Cochlear Proteins Associated with Noise-induced Hearing Loss: An Update.

Noise-induced hearing loss (NIHL) is one of the major occupational disease that has influence on the quality of life of mining workers. Several reports suggest NIHL is attributed to noise exposure at workplace and approximately 16% of hearing loss is due to it. NIHL occurs as a result of exposure to high-level noise (>85 dB) in the workplace.