3 results match your criteria: "Azienda Ospedalieria Universitaria[Affiliation]"

Predictors of Zero X-Ray Ablation for Supraventricular Tachycardias in a Nationwide Multicenter Experience.

Circ Arrhythm Electrophysiol

March 2018

From the Cardiology Department, Ospedale Alessandro Manzoni, Lecco, Italy (A.P., R.B., G.d.V.); Cardiology Department, Ospedale Treviglio e Caravaggio, Italy (G.B.); Cardiology Department, Ospedale San Bortolo, Vicenza, Italy (C.B.); Cardiology Department, Ospedale Cisanello, Azienda Ospedalieria Universitaria, Pisa, Italy (M.G.B.); Cardiology Department, Ospedale Santa Maria Nuova, Reggio Emilia, Italy (N.B.); Cardiology Department, Ospedale San Gerardo, Monza, Italy (S.d.C., G.R.); Arrhythmology Unit and Electrophysiology Laboratories, Ospedale San Raffaele, Milano, Italy (P.D.B., P.V.); Cardiology Department, Ospedale San Carlo Borromeo, Milano, Italy (D.M.); Cardiology Department, Ospedale ASO S. Croce e Carle, Cuneo, Italy (E.M.); Johnson & Johnson Med, Biosense Webster Italy, Milano (V.N.); Cardiology Department, Ospedale San Paolo, Milano, Italy (M.S.N.); Cardiology Department, Ospedale Santissima Trinità, Cagliari, Italy (S.O.); Cardiology Department, Ospedale S. Antonio Abate, Gallarate, Italy (D.O.); Cardiology Department, Ospedale San Filippo Neri, Roma, Italy (C.P.); Cardiology Department, A.S.S.T Grande Ospedale Metropolitano Niguarda, Milano, Italy (S.P.); Cardiology Department, Ospedale Guglielmo da Saliceto, Piacenza, Italy (D.P., L.R.); Cardiology Department, Ospedale San Carlo Poma, Mantova, Italy (P.P.); Cardiology Department, Azienda Ospedaliera SS. Antonio e Biagio, Alessandria, Italy (A.S.); Cardiology Department, Ospedale Multimedica, Sesto San Giovanni, Italy (A.V.); Cardiology Department, Ospedale San Francesco, Nuoro, Italy (G.V.); Cardiology Department, Ospedale Santa Maria alle Scotte, Siena, Italy (V.Z.); and Cardiology Department, Ospedale Civile, Mirano, Italy (F.Z.).

Article Synopsis
  • This multicenter study investigated factors influencing zero-fluoroscopy (ZFL) ablation procedures for supraventricular tachycardias among 430 patients.
  • Results showed ZFL was achieved in 67.2% of procedures, with key predictors including the operator’s experience, type of arrhythmia, and the patient's age.
  • The use of 3D mapping systems was effective in all cases, minimizing fluoroscopy use while maintaining high safety and effectiveness.
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Five-Year Outcomes with PCI Guided by Fractional Flow Reserve.

N Engl J Med

July 2018

From the Cardiovascular Center Aalst, Onze-Lieve-Vrouw Clinic, Aalst, Belgium (P.X., S.F., E.B., G.G.T., B.D.B.); the Department of Cardiology, Catharina Hospital, and the Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven (N.H.J.P., P.A.L.T.), and Isala Klinieken, Zwolle (J.-H.D.) - all in the Netherlands; Stanford University Medical Center and Palo Alto Veterans Affairs (VA) Health Care Systems, Stanford, CA (W.F.F.); Rigshospitalet University Hospital, Copenhagen (T.E.); Klinikum der Universität München-Campus-Innenstadt, Munich (S.K.), Heart Center Leipzig, Leipzig (A.L.), and Heart Center Dresden, Dresden (A.L.) - all in Germany; the Cardiovascular Hospital, Lyon, France (G.R.); Gottsegen Hungarian Institute of Cardiology, Budapest, Hungary (G.G.T., Z.P.); Karolinska Institutet at Södersjukhuset, Stockholm (N.W.), and Örebro University Hospital, Örebro (O.F.) - both in Sweden; Masaryk University and University Hospital, Brno (P.K.), and Na Homolce Hospital, Prague (M.M.) - both in the Czech Republic; Clinical Center Kragujevac, Kragujevac, Serbia (N.J.); Atlanta VA Medical Center, Decatur (K.M.), and Emory University School of Medicine, Atlanta (H.S.) - both in Georgia; Tulane University Heart and Vascular Institute, New Orleans (A.I.); Golden Jubilee National Hospital, Glasgow, United Kingdom (K.O.); Cardiology Unit, Azienda Ospedalieria Universitaria di Ferrara, Ferrara, and Maria Cecilia Hospital, Gruppo Villa Maria Care and Research, Cotignola - both in Italy (G.C.); Clinical Trials Unit Bern, University of Bern, Bern, Switzerland (M.R.); and the Applied Health Research Centre, Li Ka Shing Knowledge Institute of St. Michael's Hospital, Department of Medicine and Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto (P.J.).

Background: We hypothesized that fractional flow reserve (FFR)-guided percutaneous coronary intervention (PCI) would be superior to medical therapy as initial treatment in patients with stable coronary artery disease.

Methods: Among 1220 patients with angiographically significant stenoses, those in whom at least one stenosis was hemodynamically significant (FFR, ≤0.80) were randomly assigned to FFR-guided PCI plus medical therapy or to medical therapy alone.

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Cardiomyocyte Membrane Structure and cAMP Compartmentation Produce Anatomical Variation in βAR-cAMP Responsiveness in Murine Hearts.

Cell Rep

April 2018

Myocardial Function, National Heart and Lung Institute, Imperial College London, ICTEM, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK. Electronic address:

Cardiomyocytes from the apex but not the base of the heart increase their contractility in response to β-adrenoceptor (βAR) stimulation, which may underlie the development of Takotsubo cardiomyopathy. However, both cell types produce comparable cytosolic amounts of the second messenger cAMP. We investigated this discrepancy using nanoscale imaging techniques and found that, structurally, basal cardiomyocytes have more organized membranes (higher T-tubular and caveolar densities).

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