Real Time Processing and Transferring ECG Signal by a Mobile Phone.

The real-time ECG signal processing system based on mobile phones is very effective in identifying continuous ambulatory patients. It could monitor cardiovascular patients in their daily life and warns them in case of cardiac arrhythmia. An ECG signal of a patient is processed by a mobile phone with this proposed algorithm.

Does orientation of full-thickness groin grafts affect hyperpigmentation in burn contracture and syndactyly hands?

Background: Some grafts harvested from the groin area do not become hyperpigmented and in an individual with multiple pieces of grafts, the hyperpigmentation of the pieces may vary. This study evaluates the orientation of the inset of groin grafts according to their donor sites (superior-inferior) and its role in graft hyperpigmentation.

Methods: Patients with hand burn contracture or syndactyly who required at least 2 pieces of grafts were enrolled.

Pathodiagnostic parameters and evaluation of O⁶- methyl guanine methyl transferase gene promoter methylation in meningiomas.

Histopathological evaluation and grading of meningioma give important prognostic information. We evaluated retrospectively monotonous sheeting, necrosis, hypercellularity, nuclear pleomorphism, small cell changes, brain invasion, mitosis, mast cells, psammoma bodies, MIB-1 labeling index (MIB-1 LI) and histological grade of 230 primary meningioma tumors according to the latest World Health Organization (WHO) classification. To reveal any possible association between clinical features and promoter hypermethylation of O(6)-methylguanine-DNA methyltransferase (MGMT) as an important epigenetic modification in many human cancers, we also evaluated the methylation status of MGMT in meningiomas by a SYBR-green-based real-time PCR method.

Dehydroepiandrosterone stimulates nerve growth factor and brain derived neurotrophic factor in cortical neurons.

Due to the increasing cases of neurodegenerative diseases in recent years, the eventual goal of nerve repair is very important. One approach for achieving a neuronal cell induction is by regenerative pharmacology. Nerve growth factor (NGF) and brain derived neurotrophic factor (BDNF) are neurotrophins that play roles in neuronal development, differentiation, and protection.

Neuroprotective effects of Nigella sativa extract on cell death in hippocampal neurons following experimental global cerebral ischemia-reperfusion injury in rats.

Background: Global cerebral ischemia followed by reperfusion, leads to extensive neuronal damage, particularly the neurons in the hippocampal CA region. Recent studies have demonstrated that pharmacological agents, such as Nigella sativa L. (Ranunculaceae) that is an annual herbaceous flowering plant, given at the time of reperfusion afforded protection against ischemia, which is referred to as pharmacological post conditioning.

Diagnosis, classification and grading of canine mammary tumours as a model to study human breast cancer: an Clinico-Cytohistopathological study with environmental factors influencing public health and medicine.

Background: The human "Elston and Ellis grading method" was utilized in dogs with mammary tumor to examine its relation to prognosis in this species, based on a 2-year follow-up period. Although cytopathology is widely used for early diagnosis of human neoplasms, it is not commonly performed in veterinary medicine. Our objectives in this study were to identify cytopathology criteria of malignancy for canine mammary tumors and the frequency of different types of mammary lesions and their relationship with histologic grade was investigated.

Is hypertrophic pyloric stenosis a secondary disease?

Hypertrophic pyloric stenosis (HPS) is the most common gastrointestinal obstructive disease in infants which requires surgery. Typical presentation is at 4-6 weeks of life but can present very earlier or congenitally. Here we present 3 cases of HPS which presented in the first day of life with co-existing malrotation, annular pancreas, and duodenal atresia.

Assessment of the necessity of sac high ligation in inguinal hernia open surgery among children.

Background: Pediatric inguinal hernia repair is the most common operation performed by surgeons. During open operation, rupture and retraction of the hernia sac may occur. Also, dislodgement of suture ligature or clamps may allow sac retraction into the abdominal cavity.

Prevalence of asthma in children of chemical warfare victims.

Objective: Exposure of DNA to sulfur mustard gas may increase the inheritance of asthma in chemical warfare victims' (CWV) offspring. The objective of this study was to determine the prevalence of asthma in children of CWV and compare it to asthmatic children in the general population.

Methods: Four hundred and nine children from 130 CWV fathers and 440 children from 145 asthmatic parents from two cities in Iran participated in this study.

Decreased levels of soluble Toll-like Receptor 2 in patients with asthma.

Background: Recently, reports have indicated a role for the membrane form of Toll-like Receptor 2 (TLR2) in asthma pathogenesis. In this study we examined soluble TLR2 levels in serum and sputum of asthmatic and healthy subjects.

Methods: Serum and sputum samples were obtained from 33 asthmatic and 19 healthy subjects.

Cervicofacial emphysema and pneumomediastinum following dental extraction: case report.

Background: Pneumomediastinum is commonly caused by iatrogenic injury such as surgery on the cervical planes and chest or by tracheostomy. It is also well known that emphysema may occur after dental treatments using an air turbine drill, but there have been few cases of emphysema which extended to the mediastinum.

Case Presentation: A 16-year-old boy is presented with subcutaneous emphysema and pneumomediastinum which developed 24 hours after surgery for extraction of an inferior second molar.

Pneumothorax after mechanical ventilation in newborns.

Objective: Air leak syndromes including pneumothorax, pneumomediastinum and pulmonary interstitial emphysema are frequent in neonatal period. Mechanical ventilation with positive pressure is one of the most common causes of these syndromes. The aim of this study was to evaluate predisposing factors and incidence of pneumothorax in newborns under mechanical ventilation.

Corneal Crosslinking for Keratoconus in Iranian Patients: Outcomes at 1 year following treatment.

Aim And Design: A retrospective, nonrandomized, single-center clinical study was designed to evaluate the outcomes of corneal collagen crosslinking (CXL) for progressive keratoconus in Iranian patients 12 months after CXL.

Settings: This study was carried out at Navid Didegan Eye Center, a private clinic, Mashhad, Iran.

Materials And Methods: Ninety-two eyes of 53 subjects with progressive keratoconus were evaluated in this study.

Peripheral bronchopathia osteochondroplastica.

Tracheobronchopathia osteochondroplastica refers to the abnormal presence of osseous and/or cartilaginous nodules in the submucosa of the trachea and/or bronchi. This disease presents with exophytic lesions that are covered by normal mucosa. In this study, we report the case of a 51-year-old man who complained of exertional dyspnea.

Anatomical and pollen ornamentation study on Hymenocrater species in North East of Iran.

The present study tends to investigate the anatomy and palynology of Hymenocrater species in Northeast of Iran. To conduct the comparative study of anatomy characters, sections from stem and leaf were prepared using microtome and differential staining. In this part of investigation, arrangement of vessel in stem, stoma type and arrangement of mesophyll in leaf were studied.

Association of HTLV1 infection and esophageal squamous cell carcinoma.

Background: Both esophageal carcinoma and HTLV-1 (Human T cell lymphotropic virus 1) have high prevalence in northeastern of Iran.

Objective: To assess the presence of HTLV-1 genome in esophageal cancerous tissue and in tissues from non cancerous individuals.

Methods: Eighty five patients with esophageal squamous cell carcinoma and 48 non-cancerous control patients that underwent esophagogasteroscopy for other reasons were included in this study.

Impact of tree species on nutrient stocks in the forest floors of a temperate forest ecosystem.

To investigate the effect of silvicultural methods on forest floor C, N and elements stocks an experiment was carried out by sampling the forest floors of a 100-120-years-old species including beech, Norway spruce and mixed beech-spruce at the Solling forest, Germany. While the stocks of carbon and nitrogen in the forest floors of pure beech and spruce were significantly influenced by species specific differences of litter quality (p < 0.001), no significant differences were detected between pure and mixed species stands.

Typhoid myopathy or typhoid hepatitis: a matter of debate.

Purpose: The aim of the present study was to evaluate the major source of increased serum enzyme level in typhoid fever and to determine the most relevant clinical entity, hepatitis or myopathy, during typhoid fever.

Methods: A total of 118 subjects proved to have typhoid fever were evaluated for serum enzymes such as transaminases, alkaline phosphatase, lactate dehydrogenase (LDH) and creatinine kinase (CK); and their relation with each other, clinical symptoms and serum bilirubin were evaluated by regression methods.

Results: Hepatomegaly was revealed in 14% of the cases and was correlated with elevated serum biliribin (5.

A hierarchical fuzzy rule-based approach to aphasia diagnosis.

Aphasia diagnosis is a particularly challenging medical diagnostic task due to the linguistic uncertainty and vagueness, inconsistencies in the definition of aphasic syndromes, large number of measurements with imprecision, natural diversity and subjectivity in test objects as well as in opinions of experts who diagnose the disease. To efficiently address this diagnostic process, a hierarchical fuzzy rule-based structure is proposed here that considers the effect of different features of aphasia by statistical analysis in its construction. This approach can be efficient for diagnosis of aphasia and possibly other medical diagnostic applications due to its fuzzy and hierarchical reasoning construction.

A differential scanning calorimetric study of the influence of copper and dodecyl trimethyl ammonium bromide on the stability of bovine alpha-lactalbumin.

Bovine alpha-lactalbumin (alpha-LA) has been studied by differential scanning calorimetry (DSC), fluorescence spectroscopy and viscometry with various concentrations of Cu2+ and DTAB to elucidate the effect of these ligands on its thermal properties. The DSC profile of dialyzed form of alpha-lactalbumin (m-alpha-LA) contrary to the undialyzed form (holo-form, h-alpha-LA) shows two temperature induced heat absorption peaks. The m-alpha-LA is not a new form of alpha-LA.

Cooperative alpha-helix formation of beta-lactoglobulin induced by sodium n-alkyl sulfates.

It is generally assumed that folding intermediates contain partially formed native-like secondary structures. However, if we consider the fact that the conformational stability of the intermediate state is simpler than that of the native state, it would be expected that the secondary structures in a folding intermediate would not necessarily be similar to those of the native state. beta-Lactoglobulin is a predominantly beta-sheet protein, although it has a markedly high intrinsic preference for alpha-helical structure.

Airway hyperresponsiveness to methacholine in chemical warfare victims.

Background: The lung is one of the most exposable organs to chemical warfare agents such as sulfur mustard gas. Pulmonary complications as a result of this gas range from severe bronchial stenosis to mild or no symptoms. Airway hyperresponsiveness (AHR) which is usually assessed as response to inhaled methacholine is the most characteristic feature of asthma.