Vaginoplasty by using amnion graft in patients of vaginal agenesis associated with Mayor-Rokitansky-Kuster-Hauser syndrome.

Background: Vaginal agenesis is congenital anomaly of the female genital tract and may occur as isolated developmental defect or as part of a complex of anomalies. The aim of this study was to determine the effectiveness of vaginoplasty by using amnion as graft in the creation of neovagina for patients with Mayor-Rokitansky-Kuster-Hauser Syndrome.

Methods: this is a retrospective study of 28 cases of vaginal agenesis associated with Mayor-Rokitansky-Kuster-Hauser Syndrome, over the period of 20 years, in which vaginoplasty was done by modified McIndoe procedure by using amnion as graft.

Type 2 diabetes mellitus: how well controlled in our patients?

Background: Type 2 Diabetes mellitus has reached epidemic proportions worldwide and Pakistan is no exception. This study was done to see the glycaemic control of our diabetic patients by estimating Glycosylated haemoglobin & Fasting blood glucose as poor control leads to significant complications causing enormous human suffering & socioeconomic burden.

Method: This Cross-sectional study was conducted on Type 2 diabetic patients coming to medical OPD and medical B ward of Ayub Teaching Hospital between March-September 2007 fulfilling the inclusion criteria.

Use of Foley's catheter and prostaglandin F-2 alpha in second trimester termination of pregnancy.

Background: Termination of pregnancy (TOP) in the second trimester is associated with three to five times higher risk of maternal morbidity and mortality than termination during first trimester. The main concern of obstetrician is to provide the most effective and safest regimen which combines the shortest expulsion interval with least side effects. This study was undertaken to compare the use of Foley's catheter with extra-amniotic instillation of PGF2 alpha for second trimester TOP so that a choice of the safer and cost-effective method could be available.

Papillon-Lefèvre syndrome.

A 9 year old male presented with keratotic plaques over the skin of his palms and soles extending onto the dorsal surface and swollen gums since the age of 4 with subsequent loss of most of his permanent dentition. These findings are consistent with Papillon-Lefèvre syndrome.

Performance of ICT-TB test in the detection of pulmonary and extra-pulmonary tuberculosis.

Background: Tuberculosis is a major public health problem of the developing nations including Pakistan. We need a simple, economical and non invasive test to make an early diagnosis of T.B.