Facile synthesis of anisotropic gold nanoparticles and its synergistic effect on breast cancer cell lines.

Gold nanoparticles (AuNPs) possess colourful light-scattering properties due to different composition, size and shape. Their unique physical, optical and chemical properties coupled with advantages, have increased the scope of anisotropic AuNPs in various fields. This study reports a green methodology developed for the synthesis of anisotropic AuNPs.

Unraveling correlative roles of dopamine transporter (DAT) and Parkin in Parkinson's disease (PD) - A road to discovery?

Parkinson's disease (PD) is a neurodegenerative disorder accompanied by depletion of dopamine(DA) and loss of dopaminergic (DAergic) neurons in the brain that is believed to be responsible for the motor and non-motor symptoms of PD. Dopamine Transporter (DAT) is essential for reuptake of DA into the presynaptic terminal, thereby controlling the availability and spatial activity of released DA. Parkin interacts with proteins involved in the endosomal pathway, suggesting that presynaptic Parkin could regulate the expression of DAT in the plasma membrane.

New design of highly sensitive and selective MoO:Eu micro-rods: Probing of latent fingerprints visualization and anti-counterfeiting applications.

Red colour light emitting Eu ions activated MoO nanophosphors (NPs) were prepared through an ultrasound assisted sonochemical method using Aloe Vera (A.V.) gel as a bio-surfactant.

Novel T-C@AgNPs mediated biocidal mechanism against biofilm associated methicillin-resistant (Bap-MRSA) 090, cytotoxicity and its molecular docking studies.

is a commonly found pathogen that can cause food-spoilage and life threatening infections. However, the potential molecular effects of natural active thymol molecules and chitosan silver nanoparticles (C@AgNPs) in bacteria remain unclear. This gap in the literature has prompted us to study the effects of thymol loaded chitosan silver nanoparticles (T-C@AgNPs) against biofilm associated proteins in methicillin-resistant (Bap-MRSA) 090 and also their toxicity, anti-cancer activity, and validation of their molecular docking.

SiO@LaOF:Eu core-shell functional nanomaterials for sensitive visualization of latent fingerprints and WLED applications.

For the first time, intense red color composite of SiO@LaOF:Eu core-shell nanostructures (NS) were fabricated via facile solvothermal method followed by thermal treatment. The obtained core-shell particles display better spherical shape and non-agglomeration with a narrow size distribution. Photoluminescence (PL) emission spectra exhibits intense peaks at ∼593 nm, 611 nm, 650 nm corresponds to D → F (J = 0, 1 and 2) Eu transitions respectively.

Withanolides against TLR4-Activated Innate Inflammatory Signalling Pathways: A Comparative Computational and Experimental Study.

Innate inflammations are dominant causes of poor health and high mortality. The pathogen-associated molecular pattern and lipopolysaccharide (LPS) are sensed by immune cells through activation of toll-like receptor 4 leading to mitogen-activated protein kinases (MAPKs) and NF-κB activations. Controlled MAPK and Nf-κB inhibitors have been proposed as potential antiinflammatory drugs.

Hydrothermal synthesis of titanium dioxide nanoparticles: mosquitocidal potential and anticancer activity on human breast cancer cells (MCF-7).

Mosquito vectors (Diptera: Culicidae) are responsible for transmission of serious diseases worldwide. Mosquito control is being enhanced in many areas, but there are significant challenges, including increasing resistance to insecticides and lack of alternative, cost-effective, and eco-friendly products. To deal with these crucial issues, recent emphasis has been placed on plant materials with mosquitocidal properties.

Apoptotic efficacy of biogenic silver nanoparticles on human breast cancer MCF-7 cell lines.

This article describes the synthesis of silver nanoparticles using the aqueous extract of as a reducing agent by sonication, espousing green chemistry principles. Biologically synthesized nanoparticle-based drug delivery systems have significant potential in the field of biopharmaceutics due to its smaller size entailing high surface area and synergistic effects of embedded biomolecules. In the present work the cytotoxic effect of biosynthesized silver nanoparticles studied by MTT assay against breast cancer cells (MCF-7 cell line) showed significant cytotoxic activity with IC value 3.

Biosynthesis of silver nanoparticles using the extract of -antiproliferative effect against prostate cancer cells.

Green synthesis of silver nanoparticles was carried out using the aqueous extract of under various experimental conditions. The aqueous extract of showed significant potential for the quick reduction of silver ions. The synthesized silver nanoparticles were characterized with UV-visible absorption spectrophotometer, XRD, SEM, and FTIR analysis.

Secondary metabolites of Eichhornia crassipes (Waterhyacinth): a review (1949 to 2011).

Eichhornia crassipes (Mart.) Solms (Waterhyacinth), an aquatic perennial herb present throughout the world, has a myriad of metabolites. Phenalenone compounds and sterols have been isolated from this plant.

Larvicidal and pupicidal activity of extracts and fractionates of Eichhornia crassipes (Mart.) Solms against the filarial vector Culex quinquefasciatus Say.

Petroleum ether, acetone, ethyl acetate, aqueous extract, methanol and ethanol fractionate of Eichhornia crassipes (Mart.) Solms was tested for their larvicidal efficacy against the different instars (I, II, III and IV) and pupae of Culex quinquefasciatus Say. The larval mortality was observed after 24 h of the treatment.