J Chromatogr B Analyt Technol Biomed Life Sci
September 2020
Civil Aviation Medical Center, Civil Aviation Administration of China, Beijing 100123, China. Electronic address:
A common phenomenon shows that ingestion of opium poppy shell-containing drugs can result in a "false-positive" urinalysis test result for mandatory or workplace heroin abuse screening. Owing to the short detection window (8 h in urine) of the characteristic heroin metabolite 6-monoacetylmorphine (6-MAM) confirmation or exclusion of heroin abusers still presents major challenges for toxicologists. In this work, we developed an ultra-performance liquid chromatography-time-of-flight mass spectrometry method (UPLC-TOF-MS) with online data acquisition and multiple post-data-mining technologies combined with a multivariate statistical and batch validation analysis workflow to assess the characteristic urine metabolites of heroin abusers.
View Article and Find Full Text PDFChemosphere
December 2020
National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China. Electronic address:
There is increasingly concern that PM constituents play a significant role in PM-related cardiovascular outcomes. However, little is known about the associations between specific constituents of PM and risk for cardiovascular health. To evaluate the exposure to specific chemicals of PM from various sources and their cardiac effects, a longitudinal investigation was conducted with four repeated measurements of elderly participants' HRV and PM species in urban Beijing.
View Article and Find Full Text PDFChina CDC Wkly
May 2020
National Institute of Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China.
Work-related musculoskeletal disorders (WMSDs) have a high prevalence and seriously harmful, which has attracted extensive attention in various countries in the world. Currently, the occurrence and rules of WMSDs in key industries are not known in China. The prevalence of WMSDs is relatively high among professional populations in key industries in China, with the most commonly affected body parts concentrated in neck, shoulders, and low back and increasing with age and working years.
View Article and Find Full Text PDFCurr Eye Res
February 2020
Beijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Ophthalmology and science Key Lab, Capital Medical University, Beijing, China.
: This study was designed to evaluate and compare the sensitivity and specificity of the Belin/Ambrósio Deviation (BADD), Corneal Biomechanical Index (CBI) and Tomographic and Biomechanical Index (TBI) for the diagnosis of keratoconus in Chinese myopic eyes prior to undergoing corneal refractive surgery.: A total of 125 patients (185 eyes) planned to undergo corneal refractive surgery were selected from the Refractive Center of Beijing Tongren Hospital between December 2017 and December 2018. They were divided into four groups: the normal group, bilateral keratoconus (BK) group, unilateral keratoconus (UK) group, and the forme fruste keratoconus (FFK) group.
View Article and Find Full Text PDFJ Neuropathol Exp Neurol
March 2018
Department of Neurology, MIND Institute, University of California at Davis, Sacramento, California.
Our previous study demonstrated caspase independent DNA fragmentation after very brief cerebral ischemia, the mechanism of which was unclear. In this study, we explore whether actin is cleaved following focal cerebral ischemia, and whether these structural changes of actin might modulate DNA fragmentation observed following focal ischemia. Results showed that a cleaved β-actin fragment was identified in brains of rats 24 hours following 10-minute and 2-hour focal ischemia.
View Article and Find Full Text PDFSci Rep
April 2017
School of Psychology, Beijing Key Laboratory of Applied Experimental Psychology, Beijing Normal University, Beijing, China.
Parental care results in increased hippocampal volumes through adaptive stress responses in developing animals. However, human studies have not yet provided consistent findings analogous to the animal literature, possibly because parental care in humans is likely intermingled with parental overprotection, as suggested by the optimal parenting theory. Here, we tested the hypothesis that the effect of parental care on offspring hippocampal volume varies as a function of parental overprotection with a large cohort of young adult participants (N = 257).
View Article and Find Full Text PDFInflammation
October 2016
Biological Engineering and Regenerative Medicine Center, Department of Orthopedics, Tongji Hospital, Tongji Medical College, HuaZhong University of Science and Technology, Wuhan, China.
Bacteria-induced inflammatory responses cause excessive bone resorption in chronic inflammatory diseases such as septic arthritis, osteomyelitis, and orthopedic implant failure. Icariine has been reported to facilitate the bone healing and reduce the occurrence of osteoporosis in clinical, moreover, laboratory studies which have proved that Icariine promotes the proliferation and differentiation of osteoblasts in vitro. The present study aimed to evaluate the effects of Icariine on lipopolysaccharide (LPS)-induced bone loss via an osteogenic-in vitro model and to elucidate the underlying molecular mechanisms.
View Article and Find Full Text PDFHum Brain Mapp
November 2016
School of Psychology, Beijing Key Laboratory of Applied Experimental Psychology, Beijing Normal University, Beijing, China.
Human neuroimaging studies have shown that people living in poverty tend to suffer hippocampal atrophy, which leads to impaired memory and learning throughout life. However, behavioral studies demonstrate that poor people with high self-esteem are often exempt from the deleterious effect of poverty and instead possess a happy and successful life. Here we investigated whether high self-esteem can buffer against the deleterious effects of poverty, as indicated by low subjective socioeconomic status (SSS), on the hippocampal gray matter volume (GMV) in a large cohort of young participants (N = 280).
View Article and Find Full Text PDFNeuroimage
May 2016
Beijing Key Laboratory of Applied Experimental Psychology, School of Psychology, Beijing Normal University, Beijing 100875, China. Electronic address:
The problem of emotion recognition has been tackled by researchers in both affective computing and cognitive neuroscience. While affective computing relies on analyzing visual features from facial expressions, it has been proposed that humans recognize emotions by internally simulating the emotional states conveyed by others' expressions, in addition to perceptual analysis of facial features. Here we investigated whether and how our internal feelings contributed to the ability to decode facial expressions.
View Article and Find Full Text PDFCurr Eye Res
October 2016
a Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab , Beijing , China.
Purpose: To elucidate the role of the protein coding laminin α1 (LAMA1) gene in pathological myopia (PM) at the transcriptional level. To achieve this, the binding affinity of single nucleotide polymorphism (SNP) rs2089760-located on the LAMA1 promoter gene-to human fetal scleral fibroblast (HFSF) nucleoprotein was investigated and its effect on LAMA1 transcriptional initiation activity was analyzed.
Methods: Binding interactions of the HFSF nucleoprotein and biotin-labeled SNP rs2089760 probe were investigated by amplifying the LAMA1 promoter gene and performing overlap extension polymerase chain reaction (PCR) to obtain the G/A mutation of LAMA1 SNP rs2089760.
J Sci Med Sport
August 2016
Department of Health Statistics, School of Public Health, Fourth Military Medical University, China. Electronic address:
Objectives: This study investigated physical activity levels and associated factors among civil servants in Xi'an, China, to provide reference data for the implementation of health improvement strategies among civil servants.
Design: A cross-section study.
Methods: A random sample of 1000 civil servants aged 18-60 years and employed by the Xi'an civic government was assessed by using the Chinese version of the International Physical Activity Questionnaire.
Int J Clin Exp Med
March 2015
Department of Otolaryngology, Shandong Provincial Qianfoshan Hospital China.
Objective: To show the efficacy and comfort of pneumatic bag packing after the endoscopic nasal surgery. Pneumatic bag packing may be recommendable in terms of comfort and efficacy after endoscopic nasal surgery. Significant findings: There were statistical significant differences between the pneumatic bag packing and the expansive sponge packing regarding subjective symptoms and objective findings after surgery.
View Article and Find Full Text PDFZhonghua Yu Fang Yi Xue Za Zhi
January 2013
Public Health Office of Civil Aviation Medical Center, Civil Aviation Administration of China, Beijing 100123, China.
Aviat Space Environ Med
October 2008
Aviation Medical Center, Neubrandenburg, Mecklenburg, Germany.
Otto Lilienthal's pioneering work on gliders helped form the basis for development of powered aircraft. His death following a glider crash in 1896 was officially ascribed to fracture of the cervical spine. However, the clinical details assembled here make it more likely that he died from head trauma with resulting complications, possibly including intracranial hematoma.
View Article and Find Full Text PDFAviat Space Environ Med
November 2005
Aviation Medical Center & Dept. of Otorhinolaryngology, Head & Neck Surgery, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, DK-2100 Copenhagen, Denmark.
Introduction: The aim of this study was to evaluate the effect of pressure-equalizing earplugs available in major airports and drugstores. No previous study has focused on preventing barotrauma using these earplugs.
Methods: Blinded and double-blinded, one type of pressure-equalizing earplugs (JetEars) was studied in 27 volunteers disposed to ear barotrauma.
Aviat Space Environ Med
January 2005
Aviation Medical Center and Department of Otorhinolaryngology, Head and Neck Surgery, FLMKL-7522, Cophenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen O, Denmark.
A perilymphatic fistula (PLF) is an abnormal communication between the inner ear and the middle ear that leaks perilymph. PLF is considered rare, but is known to occur during childbirth, straining, weightlifting, head trauma, and diving with middle ear equalizing problems. It has also, anecdotally, been described in connection with flying.
View Article and Find Full Text PDFJ Urol
June 1993
Department of Urologic Surgery, United States Army Aviation Medical Center, Fort Rucker, Alabama.
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