1 results match your criteria: "Autonomous Government Medical College[Affiliation]"
Synthesis and Characterization of Acacia-Stabilized Doxorubicin-Loaded Gold Nanoparticles for Breast Cancer Therapy.
Drug Res (Stuttg)
January 2025
Autonomous Government Medical College, Lalitpur, Uttar Pradesh, India.
Article Synopsis
- The study focuses on developing acacia gum-stabilized gold nanoparticles loaded with doxorubicin (DOX) for targeted breast cancer treatment, aiming for better therapeutic effects with fewer side effects.* ! -
- Characterization techniques like HR-TEM and FT-IR confirmed the nanoparticle's structure, while in vitro tests showed higher drug release at acidic pH typical of tumors, leading to improved efficacy.* ! -
- The DOX-AGNPs were more cytotoxic to breast cancer cells than free DOX, although stability tests indicate some limitations under storage conditions, highlighting their potential in cancer therapy.* !