1 results match your criteria: "Austria. 11 Oregon Health and Science University[Affiliation]"
Association of Kidney Graft Loss With De Novo Produced Donor-Specific and Non-Donor-Specific HLA Antibodies Detected by Single Antigen Testing.
Transplantation
September 2015
1 Department of Transplantation Immunology, University of Heidelberg, Heidelberg, Germany. 2 Department of Nephrology, University of Heidelberg, Heidelberg, Germany. 3 Department of Transplantation and General Surgery, University of Heidelberg, Heidelberg, Germany. 4 Immunology and Histocompatibility Laboratory, CHU de Quebec, Quebec, QC, Canada. 5 Department of Microbiology, Infectious Diseases and Immunology, Laval University, Quebec, QC, Canada. 6 Division of Nephrology, University Hospital Zurich, Switzerland. 7 Departments of Nephrology, Dialysis, Kidney Transplantation and Transfusion Medicine, University Hospital Centre, Rijeka, Croatia. 8 Department of Internal Medicine, University Clinic of Giessen and Marburg, Campus Giessen, Giessen, Germany. 9 Department of Immunogenetics, Institute for Clinical and Experimental Medicine (IKEM), Prague, Czech Republic. 10 Department of General and Transplant Surgery, Innsbruck Medical University, Innsbruck, Austria. 11 Oregon Health and Science University, Portland, OR.
Background: The association of donor-specific HLA antibodies (DSA) with kidney graft failure has been addressed previously; however, the majority of studies were based on small numbers of patients with graft failure.
Methods: We investigated 83 patients with failed kidney transplants for a possible association of de novo development and persistence or loss of pre-existing DSA with graft failure. Single Antigen Bead assay-detected DSA and non-DSA antibodies were compared between patients with graft loss and matched controls with functioning grafts.