6 results match your criteria: "Australia. Electronic address: jfallon@bionicsinstitute.org.[Affiliation]"
Hear Res
December 2022
Bionics Institute, Victoria, Australia; Medical Bionics Department, University of Melbourne, Victoria, Australia.
The expansion of criteria for cochlear implantation has resulted in increasing numbers of cochlear implant subjects having some level of residual hearing. The present study examined the effects of implantation surgery and long-term electrical stimulation on residual hearing in a partially deafened cat model. Eighteen animals were partially deafened, implanted and chronically stimulated.
View Article and Find Full Text PDFHear Res
July 2021
Bionics Institute, Melbourne, Victoria, Australia; Medical Bionics Department, University of Melbourne, Melbourne, Victoria, Australia.. Electronic address:
Although performance with bilateral cochlear implants is superior to that with a unilateral implant, bilateral implantees have poor performance in sound localisation and in speech discrimination in noise compared to normal hearing subjects. Studies of the neural processing of interaural time differences (ITDs) in the inferior colliculus (IC) of long-term deaf animals, show substantial degradation compared to that in normal hearing animals. It is not known whether this degradation can be ameliorated by chronic cochlear electrical stimulation, but such amelioration is unlikely to be achieved using current clinical speech processors and cochlear implants, which do not provide good ITD cues.
View Article and Find Full Text PDFJ Neurosci Methods
July 2016
Bionics Institute, Melbourne, Victoria, Australia.
Background: Current source density analysis of recordings from penetrating electrode arrays has traditionally been used to examine the layer- specific cortical activation and plastic changes associated with changed afferent input. We report on a related analysis, the second spatial derivative (SSD) of surface local field potentials (LFPs) recorded using custom designed thin-film polyimide substrate arrays.
Results: SSD analysis of tone- evoked LFPs generated from the auditory cortex under the recording array demonstrated a stereotypical single local minimum, often flanked by maxima on both the caudal and rostral sides.
Hear Res
September 2014
Bionics Institute, Australia; Department of Medical Bionics University of Melbourne, Australia; Department of Otolaryngology, University of Melbourne, Australia. Electronic address:
The aim of this study was to determine the effects of cochlear implant (CI) use on behavioral frequency discrimination ability in partially deafened cats. We hypothesized that the additional information provided by the CI would allow subjects to perform better on a frequency discrimination task. Four cats with a high frequency hearing loss induced by ototoxic drugs were first trained on a go/no-go, positive reinforcement, frequency discrimination task and reached asymptotic performance (measured by d' - detection theory).
View Article and Find Full Text PDFHear Res
September 2014
Bionics Institute, Melbourne, Victoria, Australia.
We have previously shown that neonatal deafness of 7-13 months duration leads to loss of cochleotopy in the primary auditory cortex (AI) that can be reversed by cochlear implant use. Here we describe the effects of a similar duration of deafness and cochlear implant use on temporal processing. Specifically, we compared the temporal resolution of neurons in AI of young adult normal-hearing cats that were acutely deafened and implanted immediately prior to recording with that in three groups of neonatally deafened cats.
View Article and Find Full Text PDFHear Res
March 2014
Bionics Institute, La Trobe University, Australia; Department of Medical Bionics, University of Melbourne, Australia; Department of Otolaryngology, University of Melbourne, Australia. Electronic address:
Animal behavioral studies make a significant contribution to hearing research and provide vital information which is not available from human subjects. Animal psychoacoustics is usually extremely time consuming and labor intensive; in addition, animals may become stressed, especially if restraints or negative reinforcers such as electric shocks are used. We present a novel behavioral experimental system that was developed to allow efficient animal training in response to acoustic stimuli.
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