2 results match your criteria: "Australia 4Queensland Eye Institute[Affiliation]"

Intrinsically Photosensitive Retinal Ganglion Cell Function, Sleep Efficiency and Depression in Advanced Age-Related Macular Degeneration.

Invest Ophthalmol Vis Sci

February 2017

Medical Retina and Visual Science Laboratories, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia 2School of Biomedical Sciences, Queensland University of Technology, Brisbane, Australia 4Queensland Eye Institute, South Brisbane, Australia.

Purpose: Melanopsin expressing intrinsically photosensitive retinal ganglion cells (ipRGC) input to multiple brain regions including those for pupil control, circadian rhythms, sleep and mood regulation. Here we measured ipRGC function and its relationship to sleep quality and depression in patients with advanced AMD.

Methods: The melanopsin-mediated post-illumination pupil response (PIPR) was measured in 53 patients with advanced AMD (age 78.

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The Effects of Short-Term Light Adaptation on the Human Post-Illumination Pupil Response.

Invest Ophthalmol Vis Sci

October 2016

Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), Brisbane, Australia 2Visual Science Laboratory, School of Optometry and Vision Science, Queensland University of Technology (QUT), Brisbane, Australia.

Purpose: We determine the effect of short-term light adaptation on the pupil light reflex and the melanopsin mediated post-illumination pupil response (PIPR). Inner and outer retinal photoreceptor contributions to the dark-adapted pupil response were estimated.

Methods: In Experiment A, light adaptation was studied using short wavelength lights ranging from subthreshold to suprathreshold irradiances for melanopsin signaling that were presented before (5-60 seconds) and after (30 seconds) a melanopsin-exciting stimulus pulse.

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