Unstructured Parental Feedback at A Tertiary Maternity Hospital: A Cohort Study Using Routinely Collected Health Data.

Background: Hospital care for neonates can be challenging for parents, and a negative parental experience can affect the well-being of the infant after discharge. A family-centred approach is the gold standard of care in neonatology.

Aim: This study aimed to identify common themes in voluntary unstructured feedback received from parents and caregivers of infants admitted to the neonatal intensive care unit, special care nursery or postnatal ward or followed up by neonatal outpatient services at a tertiary Australian Women and Children's Hospital.

Global foot-and-mouth disease risk assessment based on multiple spatial analysis and ecological niche model.

Foot-and-Mouth Disease is a highly contagious transboundary animal disease. FMD has caused a significant economic impact globally due to direct losses and trade restrictions on animals and animal products. This study utilized multi-distance spatial cluster analysis, kernel density analysis, directional distribution analysis to investigate the spatial distribution patterns of historical FMD epidemics.

Unified approaches in transition metal catalyzed C(sp)-H functionalization: recent advances and mechanistic aspects.

In organic synthesis, C(sp)-H functionalization is a revolutionary method that allows direct alteration of unactivated C-H bonds. It can obviate the need for pre-functionalization and provides access to streamlined and atom economical routes for the synthesis of complex molecules starting from simple starting materials. Many strategies have evolved, such as photoredox catalysis, organocatalysis, non-directed C-H activation, transiently directed C-H activation, and native functionality directed C-H activation.

Heat-Evolved Microalgae (Symbiodiniaceae) Are Stable Symbionts and Influence Thermal Tolerance of the Sea Anemone Exaiptasia diaphana.

Symbiotic cnidarians, such as sea anemones and corals, rely on their mutualistic microalgal partners (Symbiodiniaceae) for survival. Marine heatwaves can disrupt this partnership, and it has been proposed that introducing experimentally evolved, heat-tolerant algal symbionts could enhance host thermotolerance. To test this hypothesis, the sea anemone Exaiptasia diaphana (a coral model) was inoculated with either the heterologous wild type or heat-evolved algal symbiont, Cladocopium proliferum, and homologous wild-type Breviolum minutum.

Non-ionic surfactant self-assembly in calcium nitrate tetrahydrate and related salts.

Self-assembly of amphiphilic molecules can take place in extremely concentrated salt solutions, such as inorganic molten salt hydrates or hydrous melts. The intermolecular interactions governing the organization of amphiphilic molecules under such extreme conditions are not yet fully understood. In this study, we investigated the specific effects of ions on the self-assembly of the non-ionic surfactant CH(OCHCH)OH (CE) under extreme salt concentrations, using calcium nitrate tetrahydrate as a reference.

Advanced Paediatric Life Support: A 25-year journey in Australia.

Over twenty-five years ago the first Advanced Paediatric Life Support (APLS) course was held in Australia. Through the lens of quality culture in educational organisations, we can identify factors which have underpinned the evolution, sustainability and success of this course.

Systematic Review of Vaccine Strategies Against Tritrichomonas foetus Infection in Cattle: Insights, Challenges, and Prospects.

Tritrichomonas foetus is a protozoan parasite that causes bovine trichomonosis (also referred to as trichomoniasis) resulting in substantial economic loss in extensive grazing systems. The parasite colonises the reproductive tracts of both male and female cattle, being asymptomatic in males but causing early reproductive failure in infected females. This systematic review aimed to examine research manuscripts describing the development of T.

Vitronectin regulates lung tissue remodeling and emphysema in chronic obstructive pulmonary disease.

Vitronectin (VTN) is an important extracellular matrix protein in tissue remodeling, but its role in COPD is unknown. We show that VTN regulates tissue remodeling through urokinase plasminogen activator (uPA) signaling pathway in COPD. In human COPD airways and bronchoepithelial cells and the airways of mice with cigarette smoke (CS)-induced experimental COPD, VTN protein was not changed, but downstream uPA signaling was altered (increased plasminogen activator inhibitor-1, uPAR) that induced collagen and airway remodeling.

Is There Gender Disparity in RANZCR Radiation Oncology Grants and Prizes Success?

Introduction: Recent RANZCR studies have demonstrated gender disparity in research publication output of both radiation oncology (RO) trainees and specialists, favouring men. The purpose of this project was to examine success rates by gender of grant and prize (G&P) submissions to the RO Research Committee (RORC) to determine if anything needs to be done about the appraisal process to potentially address that disparity.

Methods: College records between 2011 and 2024 (where applicable) were searched by gender for one RO trainee, and two other research manuscript prizes, and two research grant rounds.

Does Pelvic Congestion Cause Bladder Symptoms-Potential New Indication to Treat Pelvic Congestion.

Background: Pelvic Congestion Syndrome (PCS) is a condition characterised by chronic pelvic pain resulting from the dilation and reflux of veins within the pelvis. While pelvic pain is the primary symptom of PCS, other associated symptoms may vary among individuals. Bladder symptoms have been commonly observed in PCS, including increased urination frequency, urinary urgency, nocturia and rarely haematuria.

Age Is Just a Number? A Retrospective Review of Cause of Death in Patients 85 Years and Over Receiving Lung Stereotactic Ablative Radiotherapy.

Introduction: Patients aged > 85 years are under-represented in research that has established stereotactic body radiotherapy (SBRT) as the standard of care in early stage non-small cell lung cancer (NSCLC) not suitable for or refusing surgery. With an ageing population in Australia, it is important to assess SBRT and cause of death (COD) in elderly patients receiving curative intent lung SBRT.

Methods: This is a multi-centre retrospective review of eligible patients treated across Australia from 2016 to 2022 with curative intent lung SBRT for early stage primary NSCLC, and aged 85 years or over.

The decision to tell or not to tell is associated with experiences of stigma and hearing aid use among adults with hearing loss.

Objectives: To explore the extent to which an international sample of adults with hearing loss experience and respond to stigma-induced identity threat; and the associations between experiences of hearing loss stigma, responses to hearing loss stigma (concealment of hearing loss), and hearing aid use.

Design: Cross-sectional online survey comprising published questionnaires and multiple response questions designed to capture five of seven constructs of the Major and O'Brien model of stigma-induced identity threat. Multivariate modelling examined factors associated with hearing aid use and concealment of hearing loss.

RETRACTION: Pentoxifylline Prevents Epileptic Seizure via Modulating HMGB1/RAGE/TLR4 Signalling Pathway and Improves Memory in Pentylenetetrazol Kindling Rats.

G. A. Badawi, M.

MaveDB 2024: a curated community database with over seven million variant effects from multiplexed functional assays.

Multiplexed assays of variant effect (MAVEs) are a critical tool for researchers and clinicians to understand genetic variants. Here we describe the 2024 update to MaveDB ( https://www.mavedb.

Interprofessional collaboration between pharmacists and community health workers: a scoping review.

Introduction: Community health workers (CHWs) help bridge the cultural gap between health services and the communities they serve. CHWs work with physicians, nurses and social workers, but little is known about their collaboration with pharmacists. This scoping review aims to describe the interprofessional collaboration between CHWs and pharmacists, the types of interventions they deliver and CHWs' and pharmacists' specific roles within these interventions.

Regular versus as-needed treatments for mild asthma in children, adolescents, and adults: a systematic review and network meta-analysis.

Background: Inhaled corticosteroids (ICS) are recommended treatment for mild asthma. We aimed to update the evidence on the efficacy and safety of ICS-containing regimens, leukotriene receptor antagonists (LTRA), and tiotropium relative to as-needed (AN) short-acting β2-agonists (SABA) in children (aged 6-11 years) and adolescents/adults.

Methods: A systematic review of randomized controlled trials (RCTs) of regular and AN treatment for mild asthma was conducted (CRD42022352384).

Postpartum depression in relation to chronic diseases and multimorbidity in women's mid-late life: a prospective cohort study of UK Biobank.

Background: Maternal short-term outcomes of postpartum depression (PPD) were widely examined, but little is known about its long-term association with multiple chronic diseases (multimorbidity) in women's later life. This study aims to assess the association of PPD with chronic diseases and multimorbidity in women's mid-late life.

Methods: This prospective cohort study included female participants in UK Biobank who attended online follow-up assessment and reported their history of PPD.

Mapping provider and consumer voices using the AACTT framework: a focus group study of advance care planning.

Background: The provision of healthcare is complex. When evidence-practice gaps are identified, interventions to improve practice across multi-level systems are required. These interventions often consist of multiple interacting components and behaviours.

Machine learning algorithms for predicting PTSD: a systematic review and meta-analysis.

This study aimed to compare and evaluate the prediction accuracy and risk of bias (ROB) of post-traumatic stress disorder (PTSD) predictive models. We conducted a systematic review and random-effect meta-analysis summarizing predictive model development and validation studies using machine learning in diverse samples to predict PTSD. Model performances were pooled using the area under the curve (AUC) with a 95% confidence interval (CI).

Major F plasmid clusters are linked with ColV and pUTI89-like marker genes in bloodstream isolates of Escherichia coli.

Background: F plasmids are abundant in E. coli, carrying a variety of genetic cargo involved in fitness, pathogenicity, and antimicrobial resistance. ColV and pUTI89-like plasmids have drawn attention for their potential roles in various forms of extra-intestinal pathogenicity.

The genomes of the most diverse AA genome rice species provide a resource for rice improvement and studies of rice evolution and domestication.

Rice (Oryza sativa) is a staple food crop globally, with origins in wild progenitors within the AA genome group of Oryza species. Oryza rufipogon and Oryza meridionalis are native to tropical Asia and Northern Australia and offer unique genetic reservoirs. Here we explored the relationships of the genomes of these wild rice species with the domesticated rice genome.

Understanding factors influencing safety and team functionality at operative vaginal birth through multidisciplinary perspectives: a mixed methods study.

Background: Operative vaginal birth (OVB) relies on effective teamwork to optimise outcomes. This study aims to explore providers' perspectives of factors influencing safety and team functionality at OVB.

Methods: This mixed methods study involved four maternity sites at Monash Health, Australia.

Burden of depressive and anxiety disorders in China and its provinces, 1990-2021: findings from the Global Burden of Disease Study 2021.

Background: Depressive and anxiety disorders constitute a major component of the disease burden of mental disorders in China.

Aims: To comprehensively evaluate the disease burden of depressive and anxiety disorders in China.

Method: The raw data is sourced from the Global Burden of Disease, Injuries, and Risk Factors Study (GBD) 2021.

Wellbeing and quality of life among parents of individuals with Fontan physiology.

Purpose: To examine global and health-related quality of life (QOL) among parents of individuals with Fontan physiology and determine associations with sociodemographic, parent and child-related health, psychological, and relational factors.

Methods: Parents participating in the Australian and New Zealand Fontan Registry (ANZFR) QOL Study (N = 151, Parent Mean age = 47.9 ± 10.