What Dyadic Internet Street Fight Videos Can and Cannot Tell Us About the Ethological, Game Theoretic, and Sex-Differentiated Phenomenology of Human Physical Aggression.

Street fight videos on the internet may provide information about little known aspects of human physical aggression, but their reliability is unclear. Analyses of 100 dyadic fight videos addressing ethological, game theoretic and sex-differentiated questions derived from research on other animals found that prefight verbalizations or gestural signals of nonaggressive or aggressive intent loosely predicted who would strike first and who would win. The head is the preferred strike target.

The global epidemiology and health burden of the autism spectrum: findings from the Global Burden of Disease Study 2021.

Background: High-quality estimates of the epidemiology of the autism spectrum and the health needs of autistic people are necessary for service planners and resource allocators. Here we present the global prevalence and health burden of autism spectrum disorder from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 following improvements to the epidemiological data and burden estimation methods.

Methods: For GBD 2021, a systematic literature review involving searches in PubMed, Embase, PsycINFO, the Global Health Data Exchange, and consultation with experts identified data on the epidemiology of autism spectrum disorder.

Near-infrared imaging retinal diagnostic applications-a review.

Objective: Near-infrared reflectance (NIR) is a commonly performed noncontact and rapid imaging technique. This paper reviews the clinical applications of NIR for diagnosing and monitoring retinal diseases.

Methods: A comprehensive search was conducted across the Pubmed database.

Recent updates of interferon-derived myxovirus resistance protein A as a biomarker for acute viral infection.

Background: Antibiotic resistance (AMR) remains a global public health threat with a high burden in sub-Saharan countries. The overuse of antimicrobials in the clinical setting is the main factor for the spread of antibiotic resistance. Diagnostic uncertainty in differentiating between bacterial and viral infections is the major contributor to antimicrobial overuse.

"I'll do it on my own, but I'm never alone"[1 p. 402]: lived experience and practitioner perspectives of autonomy in longstanding and severe eating disorder treatment and recovery-a rapid evidence review.

Purpose: To examine autonomy within treatment and recovery from longstanding and severe eating disorders (EDs).

Background: The typically early age of onset, high incidence, and prolonged duration of EDs, has a high personal, relational, and financial burden for people who experience them. Current treatment practices rely on the exertion of external control and influence which has profound impacts on people living with EDs as well as the relationship and interactions between them and their treating professionals.

Integrating modern and herbal medicines in controlling malaria: experiences of orthodox healthcare providers in Ghana.

Background: In Ghana, the government has integrated herbal medicine into the formal healthcare system in response to widespread use of traditional remedies. However, empirical evidence supporting the contribution of integrated healthcare to malaria control remains limited. This study employed a phenomenological qualitative research design to explore the experiences of medical doctors and pharmacists from the coastal, forest and savannah regions of Ghana regarding the integration of modern and herbal medicine in the treatment and control of malaria.

Risk of mortality between warfarin and direct oral anticoagulants: population-based cohort studies.

Background: Direct oral anticoagulants (DOACs) have been reported to be associated with a higher risk of mortality compared with an older alternative, warfarin using primary care data in the United Kingdom (UK). However, other studies observed contradictory findings. We therefore aimed to investigate the association between mortality and warfarin, compared with DOACs.

Effect of intracanal cryotherapy on post-operative pain in single-visit endodontic retreatment: a randomized clinical trial.

Background: This randomized clinical trial aimed to evaluate the effect of intracanal cryotherapy with 2-4 °C normal saline irrigation on post-operative pain after single-visit non-surgical root canal retreatment.

Methods: Forty-six single-rooted, single-canal teeth requiring non-surgical root canal retreatment were randomly assigned to two groups (n = 23): a cryotherapy group and a control group. All the treatments were completed during a single visit.

Can Emotionally Intelligent Mental Health Nurse Leaders Influence Workforce Sustainability? A Scoping Review.

Due to a global shortage of nursing staff, there is renewed attention on the impact of leadership and management styles on the sustainability of the nursing workforce. Emotional intelligence (EI), the ability to manage both your own emotions and to perceive and understand the emotions of others, has been implicated as a nursing management style impacting reduced turnover and greater nurse wellbeing. Despite these promising findings, there is a dearth of research on the role of emotionally intelligent leadership on the retention of mental health nurses.

Building the Community Mental Health Nursing Workforce Through a Supported Transition Programme: An Evaluation of a Competency Framework Implementation.

There is a growing focus in the Australian healthcare system of providing mental health care in a community setting. A key feature of the Royal Commission into Victoria's mental health system was to prioritise community-based care 'a system with community at its core'. Developing a skilled, flexible and competent nursing workforce is a key objective for any community-based mental health service as nurses provide a vital role in healthcare delivery.

Triangulating evidence from the GALENOS living systematic review on trace amine-associated receptor 1 (TAAR1) agonists in psychosis.

Background: Trace amine-associated receptor 1 (TAAR1) agonists offer a new approach, but there is uncertainty regarding their effects, exact mechanism of action and potential role in treating psychosis.

Aims: To evaluate the available evidence on TAAR1 agonists in psychosis, using triangulation of the output of living systematic reviews (LSRs) of animal and human studies, and provide recommendations for future research prioritisation.

Method: This study is part of GALENOS (Global Alliance for Living Evidence on aNxiety, depressiOn and pSychosis).

Effect of Nursing Practice Environment, Nurse Staffing, Overtime and Hand Hygiene on Hospital-Acquired Infections in a Tertiary Teaching Hospital.

Aims: To investigate the impact of the nursing practice environment, nurse staffing, working overtime and compliance with hand hygiene standards on hospital-acquired infections.

Design: A multi-source quantitative study.

Methods: Nursing data were collected from selected wards in one hospital between 18 January 2021 and 15 March 2021.

Feared self and morality in obsessive-compulsive phenomena.

Background: Recent studies have shown that individuals with obsessive-compulsive disorder (OCD) tend to endorse a feared self that they perceive to be immoral, insane and/or dangerous. The current study investigated the relationship between morality-related feared self, self-relevance and OC-related cognitions and behaviours such as moral deliberation, threat interpretation bias, discomfort, urge to act and likelihood of acting in OC-relevant situations in a non-clinical sample.

Method: A total of 78 participants (27 female, M = 29.

Whole grain modified Nova ultra-processed food (UPF) definitions: a cross-sectional analysis of the impact on cardiometabolic risk measures when excluding high whole-grain foods from the UPF category in Australia.

Ultra-processed foods (UPF), defined using the Nova classification system, are associated with increased chronic disease risk. More recently, evidence suggests the UPF subgroup of whole-grain breads and cereals is in fact linked with reduced chronic disease risk. This study aimed to explore associations of cardiometabolic risk measures with Nova UPF intake versus when foods with ≥25% or ≥50% whole grain are excluded from the definition.

Single-pulse transcranial magnetic stimulation of the dorsolateral prefrontal cortex does not directly affect muscle sympathetic nerve activity in humans.

Transcranial magnetic stimulation (TMS) is applied both in research settings and clinically, notably in treating depression through the dorsolateral prefrontal cortex (dlPFC). We have recently shown that transcranial alternating current stimulation of the dlPFC partially entrains muscle sympathetic nerve activity (MSNA) to the stimulus. We, therefore, aimed to further explore the sympathetic properties of the dlPFC, hypothesizing that single-pulse TMS could generate de novo MSNA bursts.

Monitoring opioid analgesic misuse, abuse and dependence: What to the data from addictovigilance tell us about the situation in France?

The opioid epidemic has emerged in the USA in the late 1990s and widespread to Canada, Australia, and the UK to a lesser extent in the more recent years. At the European level, several studies performed in different European countries have highlighted that prescription opioid use increased substantially over the last decade, and several proxies for misuse show a parallel increasing trend. The French addictovigilance experience on opioid analgesics is a good example of a specific dedicated monitoring, taking into account in a global and multisource perspective, patterns of utilization, population involved in problematic use, ways of acquisition and health complications.

Retrospective validation of the STUMBL score in a Level 1 trauma centre.

Unlabelled: Chest trauma is a common presentation to major trauma centres. Risk assessment tools have proven useful to support decision making in this group and the STUMBL (STUdy of the Management of BLunt chest wall trauma) score is one such measure that has been increasingly utilised. The aim of this study was to retrospectively validate the STUMBL score in an Australian population of patients admitted following chest trauma.

How to … Overcome Challenges in Implementing Escape Rooms in Medical Education.

Escape rooms have emerged as a dynamic educational tool in medical education, offering immersive experiences that foster critical thinking, teamwork and practical skills. Despite their potential, the implementation of escape rooms faces significant challenges, including resource limitations, curricular integration and ensuring educational effectiveness. This paper presents practical tips to address these challenges, covering aspects such as securing resources, designing scalable and inclusive activities, leveraging technology and evaluating educational outcomes.

Phase II randomized study of dostarlimab alone or with bevacizumab versus non-platinum chemotherapy in recurrent gynecological clear cell carcinoma (DOVE/APGOT-OV7/ENGOT-ov80).

Background: Recurrent gynecological clear cell carcinoma (rGCCC) has a low objective response rate (ORR) to chemotherapy. Previous preclinical and clinical data suggest a potential synergy between immune checkpoint inhibitors and bevacizumab in rGCCC. Dostarlimab, a humanized monoclonal antibody targeting programmed cell death protein 1 (PD-1), combined with the anti-angiogenic bevacizumab, presents a novel therapeutic approach.

Atypical presentation of disseminated mycobacteriosis due to Mycobacterium avium in an aged cat.

In cats, mycobacteriosis tends to present in a syndromic manner, with cases either being due to tuberculosis (TB) (in countries where TB is endemic), one of the "leprosy-like" diseases affecting the skin and subcutis, panniculitis caused by infection of subcutaneous tissues generally with rapidly growing Mycobacteria spp. or widely disseminated granulomatous disease, which is usually caused by members of the Mycobacterium avium-intracellulare complex (MAC). Disseminated MAC disease is rare, but when it occurs, usually develops in immunocompromised hosts with defective cell-mediated immunity.

Do school-based prevention programs impact co-occurring alcohol use and psychological distress during adolescence?

Background: Adolescence is a critical period for preventing substance use and mental health concerns, often targeted through separate school-based programs. However, co-occurrence is common and is related to worse outcomes. This study explores prevention effects of leading school-based prevention programs on co-occurring alcohol use and psychological distress.

ProFESS: Changing the Way Multidisciplinary Student's Professional Behaviour Lapses Are Identified and Managed. An Evaluation of Educators' Perspectives.

Background: Best practice evidence for identifying and managing professional behaviour lapses in a multidisciplinary context is lacking. This study aimed to evaluate multidisciplinary educators' attitudes and perceptions of the ProFESS (Professional standards, Ethical Behaviour and Student Support) framework and its companion Fitness for Practice model, designed and implemented at a large Australian university to address this using a behaviour change approach.

Methods: A 72-item survey based on the Context, Input, Process, Product evaluation framework was completed by 92 multidisciplinary faculty educators and analysed using descriptive and inferential statistics.