1 results match your criteria: "Austin and Repatriation Medical Centre (Austin Campus) Heidelberg[Affiliation]"
Overexpression of insulin-like growth factor binding protein-6 inhibits rhabdomyosarcoma growth in vivo.
Int J Cancer
December 2001
Department of Medicine, University of Melbourne, Austin and Repatriation Medical Centre (Austin Campus) Heidelberg, Victoria, Australia.
Rhabdomyosarcoma is the most common soft-tissue sarcoma of childhood. Rhabdomyosarcoma cell lines overexpress insulin-like growth factor-II (IGF-II), an autocrine growth factor that is inhibited by insulin-like growth factor binding protein-6 (IGFBP-6). IGFBP-6 is associated with myoblast quiescence, and expression in rhabdomyosarcoma cells is low.
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