Factors affecting waiting times to enter opioid use disorder treatment in the United States with a particular focus on potential biological sex disparity.

Aim: Opioid use disorder (OUD) is the problematic use of licit or illicit opioids. Thus far, the literature on biological sex differences in accessing treatment is scarce. Hence, we hypothesize that biological sex has a moderating effect on OUD treatment accessibility.

Left atrial septal pouch thrombus: An unusual cause of an embolic stroke.

Left-atrial septal pouch (LASP) is a newly described anatomical variant caused by incomplete fusion of the septa primum and secundum. This case visualizes LASP as a potential nidus for blood stasis and cardiac embolism and highlights the need for consideration of TEE in the work up of cryptogenic stroke.

Orbital emphysema as a result of chest tube placement for recurrent pneumothorax.

Orbital emphysema refers to the presence of air or gas within the orbital soft tissue space. Although orbital fracture due to trauma is the most common cause, iatrogenic orbital emphysema from chest tube insertion is a rare but potentially serious complication from the treatment of pneumothorax. Symptoms can range from mild crepitus of the periorbital region to permanent vision loss secondary to central retinal artery occlusion or optic neuropathy, a result of orbital compartment syndrome.

A case of dysautonomia after COVID-19 infection in a patient with poorly controlled type I diabetes.

COVID-19 has been linked to dysautonomia in the current literature, as has uncontrolled diabetes. Here, we present a case report of severe dysautonomia following a COVID-19 infection in a patient with pre-existing poorly controlled type-1 diabetes. This patient exhibited symptoms consistent with both postural orthostatic tachycardia syndrome (POTS), as well as orthostatic hypotension.

: Uncommon yet not to be missed cause of eosinophilia.

is a soil-transmitted nematode that is estimated to infect millions of people per year worldwide. However, cases are less commonly seen in the United States. This report highlights the importance of when to include in the differential diagnosis of patients presenting eosinophilia within the United States.

Extracellular Vesicles as Communicators of Senescence in Musculoskeletal Aging.

Extracellular vesicles (EVs), including exosomes and microvesicles, are released by numerous cell types. EVs are now acknowledged as playing a critical role in cell-cell communication in healthy aging as well as in age-related diseases. Recently it was shown that senescence, a key hallmark of aging, increases the secretion of EVs.

Cell loaded hydrogel containing Ag-doped bioactive glass-ceramic nanoparticles as skin substitute: Antibacterial properties, immune response, and scarless cutaneous wound regeneration.

An ideal tissue-engineered dermal substitute should possess angiogenesis potential to promote wound healing, antibacterial activity to relieve the bacterial burden on skin, as well as sufficient porosity for air and moisture exchange. In light of this, a glass-ceramic (GC) has been incorporated into chitosan and gelatin electrospun nanofibers (240-360 nm), which MEFs were loaded on it for healing acceleration. The GC was doped with silver to improve the antibacterial activity.

Autoimmune pancreatitis: What we know so far.

Autoimmune pancreatitis (AIP) is a rare, often-missed disease that involves inflammation of the pancreas and strictures of the pancreatic duct. Its prevalence and incidence in the United States remain scarce. The disease has a varied presentation and often mimics pancreatic malignancy, which can make the diagnosis challenging.

When hiccups mean something more than just a nuisance: A rare presentation of pyogenic liver abscess.

Pyogenic liver abscess (PLA) is an uncommon yet potentially fatal disease. The disease most commonly arises from biliary infection but may also result from hematogenous seeding and portal spread secondary to bowel contamination, direct seeding, or penetrating trauma. The diagnosis is suspected when there is a hepatic lesion on imaging.

Identifying factors associated with the issuance of coronavirus-related stay-at-home orders in the Middle East and North Africa Region.

The COVID-19 pandemic has not spared the Middle East and North Africa (MENA) Region. MENA is one of the most politically, socially, and economically heterogeneous regions in the world, a characteristic reflected in its governments' responses to COVID-19. About two-thirds of these governments issued coronavirus-related stay-at-home orders (SAHOs), one of the most effective tools public health officials have for slowing the spread of infectious diseases.

Epidemiology of the 2020 pandemic of COVID-19 in the state of Georgia: Inadequate critical care resources and impact after 7 weeks of community spread.

Objectives: Novel coronavirus (COVID-19) is a global pandemic currently spreading rapidly across the United States. We provide a comprehensive look at COVID-19 epidemiology across the state of Georgia, which includes vast rural communities that may be disproportionately impacted by the spread of this infectious disease.

Methods: All 159 Georgia counties were included in this study.