6 results match your criteria: "August Pi i Sunyer Biomedical Research Institute (IDIBAPS). Barcelona[Affiliation]"
Article Synopsis
- Researchers investigated the relationship between the integrity of deep medullary veins and markers of cerebral small vessel disease in patients who had experienced a recent small subcortical infarct.
- They collected data from 50 patients using 3 Tesla-MRI imaging, examining various factors such as the presence of microbleeds, white matter hyperintensities, and diffusivity measures to assess glymphatic function.
- Results indicated that several imaging variables correlated with venular integrity and small vessel disease markers, with specific measures of diffusivity showing significant associations related to the appearance of the veins.
Coronary Endothelium-Dependent Vasomotor Function After Drug-Eluting Stent and Bioresorbable Scaffold Implantation.
J Am Heart Assoc
November 2021
University Hospital of Bellvitge, Biomedical Research Institute of Bellvitge (IDIBELL) University of Barcelona, L' Hospitalet de Llobregat Spain.
Background Early generation drug-eluting stents (DESs) showed a high grade of coronary endothelial dysfunction that was attributed to lack of stent reendothelialization. Endothelium-dependent vasomotor response of current DESs and bioresorbable scaffolds (BRSs) remains unknown. This study sought to assess the device-related endothelial function of current devices and to correlate neointima healing with endothelial function.
View Article and Find Full Text PDFResponse to fluoxetine in children and adolescents: a weighted gene co-expression network analysis of peripheral blood.
Am J Transl Res
May 2020
Department of Clinical Foundations, Pharmacology Unit, University of Barcelona Barcelona, Spain.
The inconclusive and non-replicated results of pharmacogenetic studies of antidepressant response could be related to the lack of acknowledgement of its mechanism of action. In this scenario, gene expression studies provide and interesting framework to reveal new candidate genes for pharmacogenetic studies or peripheral biomarkers of fluoxetine response. We propose a system biology approach to analyse changes in gene expression induced by eight weeks of treatment with fluoxetine in peripheral blood.
View Article and Find Full Text PDFLung function trajectories in health and disease.
Lancet Respir Med
April 2019
August Pi i Sunyer Biomedical Research Institute (IDIBAPS) Barcelona, Spain; Centro de Investigación Biomédica en Red, Enfermedades Respiratorias, Instituto de Salud Carlos III (CIBER), Madrid, Spain.
The normal lung function trajectory from birth to death has three phases: a growth phase (from birth to early adulthood), a plateau phase (that lasts for a few years), and a decline phase resulting from physiological lung ageing. Numerous genetic and environmental factors can alter one or more of these phases. Evidence shows that several lung function trajectories exist throughout the life course and, importantly, that some of them are associated with substantial implications for health and disease.
View Article and Find Full Text PDFAntigen-specific immune reactions to ischemic stroke.
Front Cell Neurosci
October 2014
August Pi i Sunyer Biomedical Research Institute (IDIBAPS) Barcelona, Spain ; Department of Brain Ischemia and Neurodegeneration, Instituto de Investigaciones Biomédicas de Barcelona (IIBB), Consejo Superior de Investigaciones Científicas (CSIC) Barcelona, Spain.
Brain proteins are detected in the cerebrospinal fluid (CSF) and blood of stroke patients and their concentration is related to the extent of brain damage. Antibodies against brain antigens develop after stroke, suggesting a humoral immune response to the brain injury. Furthermore, induced immune tolerance is beneficial in animal models of cerebral ischemia.
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