4 results match your criteria: "Aubervilliers and Paris Nord University[Affiliation]"

Bidirectional interplay of sleep apnea syndrome and cardio-vascular disorders in diabetes.

Diabetes Res Clin Pract

January 2025

Department of Endocrinology-Diabetology-Nutrition, Jean Verdier Hospital, APHP, CINFO, Bondy, France. Electronic address:

Although often overlooked sleep apnea has emerged as a significant public health concern. Obstructive sleep apnea (OSA) and diabetes commonly co-exist with a vicious cycle worsening the incidence and severity of both conditions. OSA has many implications including cardiometabolic disorders and impaired cardiovascular (CV) prognosis.

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Prevalence of heart failure (HF) and diabetes are markedly increasing globally. In a population of HF patients, approximately 40% have diabetes which is associated with a more severe HF, poorer cardiovascular outcomes and higher hospitalization rates for HF than HF patients without diabetes. Similar trends were shown in HF patients with prediabetes.

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Article Synopsis
  • The spectrum of cardiorenal and metabolic diseases includes various disorders like obesity, type 2 diabetes, chronic kidney disease, and heart failure, often co-existing in the same patient due to shared physiological pathways.
  • Recent trials have shown that treatments can benefit multiple conditions simultaneously, highlighting a need for updated clinical guidance.
  • An international task force of specialists has created the DCRM 2.0 Practice Recommendations, which consist of 22 graphics to help clinicians manage these complex conditions effectively, aiming to enhance patient health and outcomes.
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In the primary care setting providers have more tools available than ever before to impact positively obesity, diabetes, and their complications, such as renal and cardiac diseases. It is important to recognise what is available for treatment taking into account diabetes heterogeneity. For those who develop type 2 diabetes (T2DM), effective treatments are available that for the first time have shown a benefit in reducing mortality and macrovascular complications, in addition to the well-established benefits of glucose control in reducing microvascular complications.

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