A Challenging Case of Miliary Tuberculosis in Pregnancy.

Miliary tuberculosis (TB) is an uncommon yet severe condition that can pose substantial risks to pregnant women and their unborn child. This case study describes a 22-year-old pregnant female at 23 weeks of gestation presented with breathlessness, fever accompanied by chills, dry cough, and loss of appetite. With no significant comorbidities, her initial symptoms were inconclusive, leading to her initial diagnosis as a case of pyrexia of unknown origin.

Atypical Mycobacterium Skin Infection in a Heart Transplant Patient.

Atypical mycobacterium infections are an uncommon cause of cutaneous infection, and they are especially rare infections of the facial region. Immunocompromised patients, such as transplant patients, are at higher risk for infections of this nature with concurrent hematogenous spread to other organ systems. We report a patient with a previous heart transplant who developed an atypical mycobacterium infection of the skin with possible dissemination to the lung.

The fall of the mycobacterial cell wall: interrogating peptidoglycan synthesis for novel anti-TB agents.

Tuberculosis (TB) caused by has been a threat to human health for thousands of years and still leads to millions of deaths each year. TB is a disease that is refractory to treatment, partially due to its capacity for in-host persistence. The cell wall of mycobacteria, rich in mycolic acid, is broadly associated with bacterial persistence together with antimicrobial and immunological resistance.

Gastric Tuberculosis Masquerading as Persistent Epigastric Pain in an Immunocompetent Patient: A Case Report.

Tuberculosis (TB), caused by , is a leading infectious disease with varied manifestations. We report a rare presentation of gastric TB in a 50-year-old immunocompetent woman from the Middle East with no prior medical history. The patient presented with persistent epigastric pain, weight loss, nausea, and vomiting over a 2-month duration.

Microbiological aspects and clinical impact of lower lung field tuberculosis: An observational cohort study in Peru.

Objectives: Approximately 40% of tuberculosis (TB) cases remain undiagnosed globally. Lower lung field TB (LLF TB) presents atypically and is often misidentified as other lung diseases, leading to diagnostic delays in resource-limited settings. It may contribute to increased TB transmission and mortality.

Primary cutaneous infections with non-tuberculous mycobacteria: a report of 6 cases.

Background: The incidence of non-tuberculous mycobacterium infection has shown a gradual increasing trend in recent years, among which cutaneous manifestations as an important aspect. This study aimed to describe the clinical features and microbiological findings in 6 cases of primary cutaneous nontuberculous mycobacterium infection.

Methods: In this retrospective study from June 2021 to June 2022, the clinical data and microbiological results of six cases diagnosed with primary cutaneous non-tuberculous mycobacterium infection in department of dermatology, Hangzhou Third People's Hospital were analyzed.

[Issues of morphological diagnosis and pathogenesis of tuberculosis].

Tuberculosis remains a serious global problem of our time. The epidemiological situation regarding tuberculosis in the Russian Federation and in Moscow is quite favorable, however, many manifestations of diseases and morphological changes in tuberculosis require a serious approach to the timely diagnosis of the disease, especially intravital morphological verification of the process. The article outlines the main aspects of the pathogenesis of tuberculosis, including deep immunosuppression associated with HIV.

Isolated pancreatic tuberculosis presenting as mucinous cystic lesion.

A young man in his early 30s presented to our hospital with upper abdominal pain radiating to the back, progressive jaundice with pruritus, low-grade fever, vomiting and significant weight loss over 4 months. The syndrome of extrahepatic biliary obstruction was considered. There was no significant past, personal or family history.

Atypical tuberculous peritonitis presenting as a peritoneal pseudocyst in an immunocompetent adult: insights from a case and literature review.

Background: Tuberculous peritonitis often presents with nonspecific symptoms that can lead to diagnostic challenges, particularly when manifesting as peritoneal pseudocysts. This study highlights the clinical complexity and diagnostic approach of tuberculous peritonitis presented as a pseudocyst in an immunocompetent adult, an atypical scenario that is rarely documented.

Case Presentation: We report a detailed case of a 41-year-old man presenting with abdominal distension, pain, and significant weight loss over four months.

Genomics Insights into Causing Infection in a Cat with Pyogranulomatous Dermatitis and Panniculitis.

(homotypic synonym: ) represents an ungrouped thermotolerant rapidly growing mycobacteria (RGM) species occasionally associated with infections and disease in humans. In this report, we describe a case of pyogranulomatous dermatitis and panniculitis due to in an immunocompetent adult cat. To the best of our knowledge, this represents the first report of infection in animals.

Atypical Mycobacterium abscessus BlaRI Ortholog Mediates Regulation of Energy Metabolism but Not β-Lactam Resistance.

Mycobacterium abscessus (Mab) is highly drug resistant, and understanding regulation of antibiotic resistance is critical to future antibiotic development. Regulatory mechanisms controlling Mab's β-lactamase (Bla) that mediates β-lactam resistance remain unknown. S.