4,516 results match your criteria: "Attikon University Hospital.[Affiliation]"

Endometriosis is a debilitating gynecological condition commonly seen in individuals designated female at birth; however, there has been limited research focused on its prevalence and impact among transgender men. This narrative review aims to fill a critical knowledge gap by exploring the epidemiology, clinical manifestations, management strategies, and quality-of-life implications of endometriosis among transgender individuals who identify as male. Specifically, this study seeks to estimate the prevalence rates and describe the symptoms experienced by transgender men undergoing testosterone therapy.

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  • Nosocomial pneumonia, particularly hospital-acquired and ventilator-associated forms, is the top killer from hospital infections in critically ill patients, significantly exacerbated by multi-drug-resistant (MDR) Gram-negative bacteria (GNB).
  • The rise of MDR-GNB pneumonia results in delayed treatments, longer hospital stays, and higher rates of illness and death, compounded by the toxic side effects of traditional antibiotics.
  • Recently approved novel antibiotics show promise in treating MDR-GNB pneumonia, but rising antibiotic resistance poses a global challenge, emphasizing the need for careful usage to extend their effectiveness and evaluating their clinical efficacy specifically for patients with nosocomial pneumonia.
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  • Hepatocellular carcinoma (HCC) is the leading type of primary liver cancer, with increasing incidence and high mortality rates, and there are currently limited curative treatment options available despite advances in diagnosis and therapy.
  • Recent advances in understanding the tumor microenvironment have brought attention to immunotherapy as a promising approach for treating advanced HCC, although only a small number of patients benefit from existing solutions.
  • The glucocorticoid-induced TNFR-related protein (GITR) shows potential as a therapeutic target for HCC due to its role in enhancing T-cell function and inhibiting regulatory T-cells, along with evidence suggesting it may aid in anti-tumor effects and liver regeneration.
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Introduction: The complex nature of xerostomia prevents the establishment of a definite cure. Recently, research has pivoted towards stem cell transplantation for glandular reconstruction. The aim of this study is to provide an updated review of the existing research, to highlight the encountered challenges and research pathways, potentially enhancing the therapeutic applications of stem cell transplantation.

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The incidence of T4b esophageal cancer with aortic invasion but without distant metastasis is estimated to be between 3.8% and 4.6% of all esophageal cancer cases.

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Infective endocarditis (IE) is a disease that may cause significant morbidity and mortality. IE is classically caused by Gram-positive microorganisms; however, Gram-negative bacteria may seldom also be the cause. species cause zoonosis and may also infect humans, mainly causing gastrointestinal infection by or invasive disease by , such as bacteremia, sepsis, meningitis, or vascular infection.

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Nonalcoholic fatty liver disease (NAFLD) poses an emerging threat topublic health. Nonalcoholic steatohepatitis (NASH) is reported to be the most rapidly rising cause of hepatocellular carcinoma in the western world. Recently, a new term has been proposed: metabolic dysfunction-associated steatotic liver disease (MASLD).

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Psoriatic arthritis (PsA) is associated with obesity and other related comorbidities, which impose an additional burden on disease activity and response to treatment. We investigated the impact of Mediterranean diet, and exercise on the presentation and severity of PsA. Three hundred fifty-five patients with PsA (n = 279) and psoriasis (PsO) (n = 76) were included in a cross-sectional study.

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Introduction: Endometriosis is a common benign condition affecting 10-15% of women of reproductive age. An unusual site of endometriosis is the canal of Nuck, which is a physiologically obliterated space in women spanning the area from the deep inguinal ring to the labia majora.

Case Presentation: A 37-year-old woman, with a past medical history of several in vitro fertilization attempts, presented with a right-sided painful inguinal mass.

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  • The European Stroke Organisation (ESO) developed guidelines for managing basilar artery occlusion (BAO) due to its poor outcomes, despite being a small percentage of strokes.
  • The guidelines were created using the GRADE methodology and involved a systematic literature review based on 10 clinical questions identified as critical (PICO).
  • The findings suggest using intravenous thrombolysis (IVT) within 24 hours for BAO patients, combined with endovascular treatments for better outcomes, but results varied depending on factors like treatment location and initial stroke severity.
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Introduction: Despite the widespread use of minimally invasive techniques, open left thoracoabdominal esophagectomy (LTE) can offer excellent visualization and adaptability. The current study aimed to present and evaluate the outcomes related to an open LTE in esophageal malignancy treatment.

Methods: A retrospective cohort analysis of data collected from two institutions was performed, including patients with distal esophageal or junctional tumors who underwent open LTE between November 2018 and December 2023.

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Renal manifestations in a cohort of pediatric patients with inflammatory bowel disease.

Arab J Gastroenterol

August 2024

Department of Paediatric Gastroenterology, Hepatology and Nutrition, 3(rd) Department of Paediatrics, Attikon University General Hospital, National and Kapodistrian University of Athens, Athens, Greece.

Background And Study Aims: Renal involvement in inflammatory bowel disease is rather uncommon. This study aims to describe the spectrum of renal involvement in pediatric patients with IBD and reduce delay in detection and management.

Patients And Methods: This is a retrospective study of the renal function of all patients, aged <18 years, who have been followed for IBD in our pediatric gastroenterology department from January 2019 till January 2023.

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Background And Purpose: Cervical artery dissection (CAD) represents a leading cause of unilateral lower cranial nerve IX-XII palsy, known as Collet-Sicard syndrome (CSS). High-resolution magnetic resonance imaging (HR-MRI) is widely used in the evaluation of patients with CAD, providing information regarding vessel wall abnormalities and intraluminal thrombus.

Methods: We present a patient with palsy of multiple lower cranial nerves in the context of CSS, attributed to unilateral spontaneous internal carotid artery dissection.

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Atrial fibrillation (AF) is the most common heart rhythm disorder, especially in people over the age of 50, which affects more than 40 million people worldwide. Many studies have highlighted the association between hypertension with the development of AF. Blood pressure variability (BPV) is a dynamic size obtained by recording blood pressure oscillations using specific readings and at specific time intervals.

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Objectives: The Thyroidectomy-Related Voice Questionnaire (TVSQ) is a useful tool in the detection of voice changes and dysfunctions and the diagnosis of other symptoms related to transient or permanent laryngeal nerve damage in patients after thyroidectomy. The aim of our study is the translation and validation of (TVSQ) in the Greek language and in Greek population for the first time.

Methods: The TVSQ was translated from English to Greek and vice versa by two independent researchers, while before the application of the TVSQ in clinical practice, a control group of 20 people was used.

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  • The STRONG-HF trial tested the effectiveness of rapidly increasing neurohormonal blockade in patients with acute heart failure (AHF) compared to usual care.
  • Patients receiving high-intensity care (HIC) showed significantly higher rates of successful decongestion at day 90 (75%) compared to usual care (68%), alongside improvements in various decongestion markers.
  • Successful decongestion was linked to a lower risk of hospital readmission or all-cause death, indicating that the HIC approach offers better long-term outcomes for AHF patients.
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  • * A study involving 52 stage III/IV NSCLC patients showed that 44% had detectable pre-existing T cells specific to tumors, and those patients had better median overall survival rates compared to those without these T cells.
  • * The research highlighted that patients with pre-existing T cells and low levels of certain immunosuppressive cells had a significant survival advantage, suggesting that evaluating these immune cell characteristics could help identify which patients are likely to benefit most from immunotherapy.
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  • - This study introduces a new method, FFR2D, for quickly and accurately calculating fractional flow reserve using routine 2D coronary angiograms, comparing its effectiveness to the traditional pressure wire measurement in assessing coronary artery stenosis.
  • - Conducted with 88 patients, the results showed that FFR2D had a strong correlation with the invasive FFR, achieving a diagnostic accuracy of 90.9%, with key metrics including 85.7% sensitivity and 93.3% specificity for identifying critical artery blockages.
  • - FFR2D outperformed the standard 50% diameter stenosis measurement in predictive ability, demonstrating a significantly higher area under the ROC curve, indicating its potential as a more reliable tool
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: Real-world data show limited utilization of direct oral anticoagulants (DOACs) in obese patients (body mass index [BMI] ≥ 30 kg/m) due to concerns regarding their efficacy and safety in this demographic. : This review aimed to consolidate current evidence on the efficacy and safety of DOACs versus warfarin in obese patients with non-valvular atrial fibrillation (AF) or venous thromboembolism (VTE). The primary efficacy outcome assessed a composite of all-cause mortality, stroke, systemic embolism (SE), and myocardial infarction (MI).

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  • The EUCAST Antifungal Susceptibility Testing Subcommittee (AFST) has been refining antifungal susceptibility testing methods for yeast, moulds, and dermatophytes since 2002, including setting epidemiological cut-off values and breakpoints.
  • Key challenges for yeasts like fluconazole resistance and variability in testing methods have been addressed, ensuring reliable clinical recommendations even for rare yeast species.
  • Recent initiatives focus on developing methods to detect antifungal resistance in specific species and creating guidance for molecular testing, while the adoption of EUCAST breakpoints in commercial tests requires careful validation to align with established reference standards.
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Objective: This study investigates the association of Body Mass Index (BMI) and age of epilepsy onset, in patients with epilepsy associated with temporal encephaloceles (TEs).

Methods: A comprehensive PubMed literature review was conducted using the keywords "temporal encephaloceles" and "epilepsy" for identifying articles for the analysis. Inclusion criteria encompassed all evidence levels reporting patients with TE-related epilepsy and documented BMI.

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Backround: Metabolic-dysfunction Associated Steatotic Liver Disease (MASLD) has been associated with increased cardiovascular risk. The aim of this Randomized Double-blind clinical Trial was to evaluate the effects of coenzyme-Q10 supplementation in patients with MASLD in terms of endothelial, vascular and myocardial function.

Methods: Sixty patients with MASLD were randomized to receive daily 240 mg of coenzyme-Q10 or placebo.

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