7 results match your criteria: "Atsuta Clinic[Affiliation]"
Causative diseases of bloody sputum and hemoptysis in respiratory clinics in Japan.
Respir Investig
January 2025
Department of Pulmonology, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, Kanagawa, 236-0004, Japan.
Background: No previous studies have compared respiratory clinics and respiratory specialized facilities regarding causative diseases for bloody sputum and hemoptysis in Japan.
Methods: We retrospectively compared causative diseases for bloody sputum and hemoptysis between 3 respiratory clinics (clinic group) and 7 departments of respiratory medicine at hospitals (hospital group) in Japan.
Results: We collected data from 231 patients (median age, 51 years; age range, 24-96 years; 109 men (47.
Prevalence and causes of subacute cough in Japan.
Respir Investig
January 2025
Department of Respiratory Medicine, Allergy and Clinical Immunology, Nagoya City University Graduate School of Medical Sciences, 1 Kawazumi Mizuho-machi, Nagoya, 467-860, Japan.
Article Synopsis
- Subacute cough is a specific type of cough lasting 3-8 weeks and is primarily caused by cough variant asthma, atopic cough, and sinobronchial syndrome, rather than post-infectious cough as previously believed.
- In a study involving 148 patients, 68.3% developed chronic cough, often stemming from multiple underlying conditions such as cough variant asthma combined with atopic cough.
- The findings highlight the need for careful diagnosis and treatment of multiple causes in patients with subacute cough to prevent progression to chronic cough.
Prevalence and causes of chronic cough in Japan.
Respir Investig
May 2024
Department of Respiratory Medicine, Allergy and Clinical Immunology, Nagoya City University Graduate School of Medical Sciences, 1 Kawazumi Mizuho-machi, Nagoya, 467-860, Japan.
Article Synopsis
- Chronic cough is a prevalent symptom in respiratory diseases that significantly impacts patients' lives and social interactions, highlighting the need for comprehensive studies in Japan.
- The study involved 379 patients with a cough lasting over 8 weeks, ultimately analyzing 334 cases, revealing major causes like cough variant asthma and sinobronchial syndrome.
- Findings indicate that patients with gastroesophageal reflux-associated cough had a lower treatment success rate and that undiagnosed cases took longer to treat, marking this as Japan's first nationwide investigation into chronic cough causes and treatments.
Histological characteristics of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinases-1 in asthmatic murine model during A(H1N1)pdm09 infection.
Pathol Int
October 2022
Department of Pediatrics, Yamaguchi University Graduate School of Medicine, Ube, Japan.
Pandemic influenza virus A(H1N1)pdm09 infection occurred in healthy children and young adults, but asthmatic patients presented more rapid progression of respiratory distress and plastic bronchitis. To investigate the pathogenesis of worsening respiratory symptoms after A(H1N1)pdm09 infection, we focused on matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinases-1 (TIMP-1). MMP-9 and TIMP-1 levels in bronchoalveolar lavage fluid and serum from mice with and without asthma were evaluated after A(H1N1)pdm09 or seasonal A(H1N1) infection.
View Article and Find Full Text PDFMepolizumab decreased the levels of serum galectin-10 and eosinophil cationic protein in asthma.
Asia Pac Allergy
July 2021
Division of Respiratory Medicine, Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan.
Background: Mepolizumab, a humanized antibody targeting interleukin-5, decreases the number of blood eosinophils and the frequency of exacerbation of severe asthma. Galectin-10 is a protein within the cytoplasm of eosinophils and constitutes Charcot-Leyden crystals, which promotes key features of asthma. However, the relationship between time kinetics and clinical response of eosinophil-derived molecules such as galectin-10 or eosinophil cationic protein (ECP) has not been precisely investigated.
View Article and Find Full Text PDFEnhanced airway hyperresponsiveness in asthmatic children and mice with A(H1N1)pdm09 infection.
Immun Inflamm Dis
June 2021
Department of Pediatrics, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan.
Background: Severe asthma exacerbation is an important comorbidity of the 2009 HIN1 pandemic (A(H1N1)pdm09) in asthmatic patients. However, the mechanisms underlying severe asthma exacerbation remain unknown. In this study, airway hyperresponsiveness (AHR) was measured in pediatric asthma patients infected with A(H1N1)pdm09.
View Article and Find Full Text PDFCauses and Solutions of the Trampoline Effect.
Contrib Nephrol
June 2016
Atsuta Clinic, Nagoya, Japan.
Article Synopsis
- A trampoline effect happens when a buttonhole tract and vessel flap aren't aligned properly, leading to complications.
- Using multiple punctures on an arteriovenous fistula (AVF) to create a buttonhole tract may lower the risk of this effect by enlarging the puncture with each needle insertion.
- Using a new dull needle to enlarge the vessel flap during a single buttonhole cannulation may help address issues with the trampoline effect, and inserting the needle in reverse could lead to smoother procedures.