A Descriptive Analysis of the Seasonal Patterns of Bone Stress Injury Incidence in Division I Collegiate Distance Runners.

Background: A bone stress injury (BSI) is a common overuse injury in collegiate athletes, particularly cross-country and track and field runners. Limited work describes the seasonality of BSIs or the differences in rates and anatomic locations of BSIs in collegiate runners.

Purpose: To describe seasonally related trends in anatomic locations of BSIs in National Collegiate Athletic Association (NCAA) Division I male and female middle- and long-distance runners.

Return to Sport After Distal Biceps Tendon Repair: A Systematic Review.

Background: Ruptures of the distal biceps tendon (DBT) can affect the range of motion and strength of the elbow, raising concerns for patients seeking to restore normal function and engage in their regular activities, particularly returning to previous levels of sport participation.

Purpose: To characterize and assess the rate and timing of return to sport (RTS) after DBT repair.

Study Design: Systematic review; Level of evidence, 4.

The Statistical Fragility of Functional Outcomes for Arthroscopic Rotator Cuff Repair With and Without Acromioplasty: A Systematic Review and Meta-analysis.

Background: Views surrounding acromioplasty at the time of arthroscopic rotator cuff repair (RCR) have shifted dramatically over time. In recent years, various studies have argued against acromioplasty, citing equivocal functional outcomes after arthroscopic RCR with or without acromioplasty.

Purpose: To assess the statistical fragility of functional outcomes after arthroscopic RCR with and without acromioplasty using the reverse continuous fragility index (RCFI).

Return to Sport and Graft Failure Rates After Primary Anterior Cruciate Ligament Reconstruction With a Bone-Patellar Tendon-Bone Versus Hamstring Tendon Autograft: A Systematic Review and Meta-analysis.

Background: Anterior cruciate ligament (ACL) tears are frequent injuries in athletes that often require surgical reconstruction so that patients may return to their previous levels of performance. While existing data on patient-reported outcomes are similar between bone-patellar tendon-bone (BTB) and hamstring tendon (HT) autografts, the literature regarding return to sport (RTS), return to previous levels of sport activity, and graft failure rate remains limited.

Purpose: To compare rates of RTS, return to previous activity levels, and graft retears among athletes undergoing primary ACL reconstruction using a BTB versus HT autograft.

Orthopedic Patients Are Highly Amenable to Cannabis-Based Products for the Treatment of Musculoskeletal Pain.

Background: Tetrahydrocannabinol (THC)-based and cannabidiol (CBD)-based products are increasing in popularity for the management of pain. Cannabis-based products may serve as a valuable alternative to traditional analgesics such as opioids for pain management among orthopedic patients. The purpose of this study was to investigate the perspective of orthopedic sports medicine patients regarding the use of THC- and CBD-based products for the management of musculoskeletal pain.

Pulmonary function in swimmers exposed to disinfection by-products: a narrative review.

Swimming produces many psychophysiological effects, including blood, hormonal, enzymatic, pulmonary, cardiovascular and energetic adaptations. However, asthma and allergies are becoming increasingly prevalent medical issues among elite endurance-trained swimmers, where exercise-induced asthma or bronchospasm is frequently reported. Heavy endurance swimming training, especially under adverse conditions, stresses the airway mucosa, leading to inflammatory changes, as observed in induced sputum in competitive swimmers.

Epidemiology of Wrestling Injuries in Female Athletes at US Emergency Departments.

Purpose Wrestling injuries in female athletes is an understudied topic. The aim of this study is to characterize the injuries that occur in female wrestlers aged five to 18 who presented to United States (US) emergency departments (ED) from 2014-2023 and compare patterns between youth and adolescent wrestlers. Method This was a retrospective comparative study including female patients aged five to 18 years of age presenting to the ED due to an injury related to their participation in the sport of wrestling.

Sudden Onset of Unexplained Leg Pain Following Open Reduction and Internal Fixation of a Displaced Tibial Tuberosity Fracture: A Case Report of Deep Venous Thrombosis in an Adolescent Athlete.

This case report presents a 16-year-old basketball player, who developed deep venous thrombosis (DVT) following surgical intervention for a displaced tibial tuberosity fracture and forearm fractures. Despite few identifiable thrombotic risk factors, the patient's postoperative course was complicated by unexplained leg pain, fever, and ultimately confirmed DVT. Prompt management with therapeutic anticoagulation and multidisciplinary care led to favourable outcomes.

Heterogeneity in the use of osseous risk factors and limited use of relevant patient-reported outcome measurements in studies investigating treatment of patellar dislocation: A scoping review.

Purpose: The treatment of patellar dislocation is tailored based on the presence or absence of osseous risk factors. The purpose of this scoping review was to investigate whether existing research addresses patient differences by mapping the use of osseous risk factors and patient-reported outcome measures (PROMs) in studies investigating the treatment of patellar dislocation.

Methods: This study was a scoping review conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analysis extension for Scoping Reviews.

Correlation of King-Devick Test and Helmet Impact Exposures Over a Youth Football Season.

Background: The cumulative effect of repetitive subconcussive head impacts on neurocognitive function during youth contact sports remains largely unknown. There is a paucity of literature evaluating cumulative helmet forces over a season and their correlation with preseason and postseason cognitive performance tasks such as the King-Devick test (KDT).

Hypothesis: Higher helmet forces recorded throughout a 10-week, 10-game youth football season would correlate with slower performance on postseason KDT.

Clinical outcomes of arthroscopic modified suture augmentation versus InternalBrace™ reconstruction in the treatment of chronic ankle instability.

Background: At present, the modified suture augmentation (MSA) repair and the InternalBrace™ (IB) reconstruction techniques are commonly used for the treatment of chronic ankle instability (CAI). This study aimed to evaluate and compare the clinical efficacy of the MSA repair and IB reconstruction techniques, providing a reference for clinical practice.

Methods: After propensity score matching, 50 patients with CAI between May 2021 and May 2022 were included in this retrospective study.

Varus/valgus angle of the femoral component relative to the tibial component increases risk of bearing dislocation in medial mobile bearing unicompartmental knee arthroplasty.

Background: In medial mobile-bearing unicompartmental knee arthroplasty (MB-UKA), the position of the bearing does not correspond to the planned position which will increasing the risk of bearing dislocation. This study aimed to explore the relationship between the malposition of the femoral and tibial components and the phenomenon of bearing deviation using postoperative radiological measurements.

Methods: One hundred twenty patients who underwent mobile-bearing uni-compartmental knee arthroplasty (MB-UKA) at our hospital between January and August 2023 were enrolled in this retrospective study.

Resveratrol Upregulates miR-124-3p Expression to Target DAPK1, Regulating the NLRP3/Caspase-1/GSDMD Pathway to Inhibit Pyroptosis and Alleviate Spinal Cord Injury.

Currently, an effective treatment for spinal cord injury (SCI) is not available. Due to the irreversible primary injury associated with SCI, the prevention and treatment of secondary injury are very important. In the secondary injury stage, pyroptosis exacerbates the deterioration of the spinal cord injury, and inhibiting pyroptosis is beneficial for recovery from SCI.

Negative Prognostic Factors and Clinical Improvement Prediction Modeling for ESWT in Calcific Shoulder Tendinitis Using Artificial Intelligence Techniques.

Background: The efficacy of extracorporeal shockwave therapy (ESWT) for treating shoulder calcific tendinitis can be influenced by various prognostic factors. This study aimed to identify prognostic factors associated with the failure of ESWT for symptom relief and to evaluate the predictive capability of the eXtreme Gradient Boosting (XGBoost) algorithm of artificial intelligence techniques in this context.

Methods: This retrospective study enrolled patients with persistent shoulder pain attributed to calcific tendinitis who underwent ESWT after failed conservative treatment between January 1998 and December 2022.

Heavy resistance training provides short-term benefits on bone formation in well-functioning older adults.

Objectives: Maintained bone health is critical for independent living when aging. Currently, multimodal exercise regimes including weight-bearing exercises with impact are prescribed as optimal for maintaining bone health, while there is less consensus on the effects of resistance training at different intensities upon bone. Here we examined whether bone health was positively influenced by 1 year of supervised resistance training at two different intensities.

Combination of rTMS and oxytocin agonist attenuate depression-like behavior after postpartum depression in mice.

The Diagnostic and Statistical Manual of Mental Disorders (DSM-5) categorizes postpartum depression (PPD) as a subtype of Major Depressive Disorder (MDD) with peripartum onset, generally arising within the initial trimester following delivery. This acute psychiatric condition is characterized by feelings of worthlessness, insomnia, extreme anxiety, or maternal neglect. Intranasal oxytocin (OT) and transcranial magnetic stimulation (TMS) have the potential to address impaired social cognition; nonetheless, their neuronal underpinnings, along with their safety and efficacy, are little comprehended.

Unloader brace or high tibial osteotomy in the treatment of the young patient with medial knee osteoarthritis: a randomized controlled trial.

Background And Purpose:  For medial knee osteoarthritis (OA), operative and nonoperative treatment options are available. Two widely applied unloading therapies are a valgus unloader brace and a high tibial osteotomy (HTO). We aimed to compare the effects of a valgus unloader knee brace with an HTO on knee pain after 1 year in patients with symptomatic medial knee OA.

Aerobic exercise regulates gut microbiota profiles and metabolite in the early stage of Alzheimer's disease.

Aerobic exercise (AE) has been shown to offer significant benefits for Alzheimer's disease (AD), potentially influencing the gut microbiota. However, the impact of changes in intestinal flora in early Alzheimer's disease induced by aerobic exercise on metabolic pathways and metabolites is not well understood. In this study, 3-month-old APP/PS1 and C57BL/6 mice were divided into two groups each: a control group (ADC for APP/PS1 and WTC for C57BL/6) and an aerobic exercise group (ADE for APP/PS1 and WTE for C57BL/6).

Go big or spin fast? Biomechanical deterministic models for snowboard freestyle tricks performed on a trampoline.

In snowboard freestyle, rotation is the key indicator of trick difficulty, encouraging riders to perform tricks with more rotation. In many cases, snowboarders learn and practice tricks using training tools such as trampolins and/or landingbags before they transfer this tricks on-snow. It has not yet been scientifically investigated which movement parameters are primarily responsible for the acquisistion of increasingly difficult cork tricks.

Public perceptions of meniscus tears: Evaluating knowledge gaps and the role of education.

Background: Meniscus tears are common, occurring acutely during sports or as degenerative tears with aging. Limited information exists about the public's understanding of these injuries and their management.

Hypothesis/purpose: This study aimed to evaluate the public's baseline understanding of meniscus tear management and assess the effectiveness of an educational intervention to improve their understanding.

Chronic reactive synovitis in patients undergoing ACL reconstruction and augmentation with tape-type sutures.

Introduction: Arthroscopic Anterior Cruciate Ligament Reconstruction (ACLR) with internal bracing and augmentation using tape-type sutures (TTS) has gained popularity due to its biomechanical advantages. However, concerns have emerged regarding chronic reactive synovitis, which can lead to graft failure and the need for revision surgery. The purpose of this research is to determine the prevalence of chronic reactive synovitis after TTS-reinforced ACLR.

Microfluidic Synthesis of miR-200c-3p Lipid Nanoparticles: Targeting ZEB2 to Alleviate Chondrocyte Damage in Osteoarthritis.

Introduction: Osteoarthritis (OA) is a degenerative joint disease characterized by articular cartilage degeneration. Chondrocyte inflammation, apoptosis, and extracellular matrix degradation accelerated OA progression. MicroRNA (miRNA) has the potential to be a therapeutic method for osteoarthritis.

Fibrocyte enrichment and myofibroblastic adaptation causes nucleus pulposus fibrosis and associates with disc degeneration severity.

Fibrotic remodeling of nucleus pulposus (NP) leads to structural and mechanical anomalies of intervertebral discs that prone to degeneration, leading to low back pain incidence and disability. Emergence of fibroblastic cells in disc degeneration has been reported, yet their nature and origin remain elusive. In this study, we performed an integrative analysis of multiple single-cell RNA sequencing datasets to interrogate the cellular heterogeneity and fibroblast-like entities in degenerative human NP specimens.