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High mortality within 90 days of diagnosis in patients with Cushing's syndrome: results from the ERCUSYN registry.

Eur J Endocrinol

November 2019

Institute of Medicine at Sahlgrenska Academy, University of Gothenburg and the Department of Endocrinology, Sahlgrenska University Hospital, Gothenburg, Sweden.

Objective: Patients with Cushing's syndrome (CS) have increased mortality. The aim of this study was to evaluate the causes and time of death in a large cohort of patients with CS and to establish factors associated with increased mortality.

Methods: In this cohort study, we analyzed 1564 patients included in the European Registry on CS (ERCUSYN); 1045 (67%) had pituitary-dependent CS, 385 (25%) adrenal-dependent CS, 89 (5%) had an ectopic source and 45 (3%) other causes.

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Article Synopsis
  • Diabetes self-management education is essential for effectively managing diabetes, focusing on improving metabolic control and quality of life.
  • Negative attitudes towards insulin therapy are common among patients with type 2 diabetes, stemming from feelings of failure and fear of restrictions or complications.
  • Health care professionals should prioritize understanding patients’ concerns through active listening rather than simply convincing them to undergo insulin treatment.
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