Effects of L. Extract and Apocynin on Lens Oxidative Damage and Boron Levels in Rats with a High Fat-Diet.

Objectives: Nutritional obesity causes oxidant damage in the body and cataract formation in the lenses by increasing the formation of free radicals. Myrtus communis leaf extracts (Myr) have antioxidant properties, and apocynin (Apo) is an effective NADPH-oxidase inhibitor. The data on tissue boron levels are quite lacking.

Synthesis and Aldose Reductase Inhibition Effects of Novel N-Benzyl-4-Methoxyaniline Derivatives.

In the current study, starting from 4-methoxyaniline, four Schiff bases were synthesized from benzaldehydes with Br and OMe. Corresponding N-benzylanilines and their derivatives were obtained from reductions (by NaBH ) and substitutions (by acyl and tosyl chlorides) of these bases, respectively. The inhibitory effects of the sixteen compounds, twelve of which were novel compounds are examined.

Photon interaction performance of various contrast agents: Theoretical and simulation results.

In this study, total mass attenuation coefficient (μ/ρ) values in the energy range from 60 keV to 15 MeV for some contrast agents (Iopamidol, Metrizamide, Iohexol, Ioxaglic acid, Iopromide, Ioversol and Iopentol) were determined with the WinXCOM computer program and GEANT4 computer simulation code. Linear attenuation coefficients (μ), half value layers (HVL), tenth value layers (TVL), mean free paths (mfp), effective atomic numbers (Z) and effective electron densities (N) in the aforementioned energy range were obtained with the help of the calculated total mass attenuation coefficients. Energy absorption build-up factors (EABF) and exposure build-up factors (EBF) for contrast agents were calculated using the five-parameter geometric progression (G-P) fitting method in the energy region of 0.

Digitalization in education during the COVID-19 pandemic: emergency distance anatomy education.

Purpose: During the COVID-19 pandemic, the distance education method started to be applied to prevent the interruption of education in universities. Anatomy education given to students who will serve in the field of health has also been transferred to the online method in this digitization process. The aim of the study was to evaluate the emergency distance anatomy education by taking the feedback of the students of the health services vocational school and to make changes and regulations that will increase the quality of education.

The effects of hand deformity on upper-limb function and health-related quality of life in children with spastic hemiplegic cerebral palsy.

The aim of this study was to investigate the effect of hand deformity on upper-limb function and health-related quality of life (HRQOL) in children with hemiplegic cerebral palsy (CP). The study included 44 children with hemiplegic CP between the ages of 6 and 14 years (mean age, 10.04 years; SD, 3.

Potentially Inappropriate Medication Use in Older People: A Crosssectional Study Using Beers Criteria.

Background: The use of Potentially Inappropriate Medications (PIMs) is common and negatively affects elderly health and disease prognosis.

Objective: This study aims to analyze the frequency of PIMs in the elderly health records registered to a family health center and to identify risk factors, prescription/nonprescription distribution, distribution by healthcare institutions, number of doctors visits, and health literacy.

Methods: In this cross-sectional study, a stratified sampling method was used to select individuals aged ≥ 65 years.

Investigation of possible neuroprotective effects of some plant extracts on brain in bile duct ligated rats.

This study aimed to investigate the possible neuroprotective effects of bitter melon (BM), chard, and parsley extracts on oxidative damage that may occur in the brain of rats with bile duct ligation (BDL)-induced biliary cirrhosis. It was observed that lipid peroxidation (LPO), sialic acid (SA), and nitric oxide (NO) levels increased; glutathione (GSH) levels, catalase (CAT) activity, and tissue factor (TF) activity decreased significantly in the BDL group. However, in groups with BDL given BM, chard, and parsley extracts LPO, SA, NO levels decreased; GSH levels and CAT activities increased significantly.

Sensitive determination of Fluoxetine and Citalopram antidepressants in urine and wastewater samples by liquid chromatography coupled with photodiode array detector.

A new analyte separation and preconcentration method for the trace determination of antidepressant drugs, Fluoxetine (FLU) and Citalopram (CIT) in urine and wastewaters, was developed based on HPLC-DAD analysis after magnetic solid phase extraction (MSPE). In the proposed method, FLU and CIT were retained on the newly synthetized magnetic sorbent (FeO@PPy-GO) in the presence of buffer (pH 10.0) and then were desorbed into a lower volume of acetonitrile prior to the chromatographic determinations.

The Popularity of the Biologically-Based Therapies During Coronavirus Pandemic Among the Google Users in the USA, UK, Germany, Italy and France.

Object: The aim of this retrospective infodemiological study was to evaluate people's interests in biologically-based (B-B) complementary and alternative medicine (CAM) therapies such as herbs, foods, and supplements during the coronavirus pandemic via analysis of Google search engine statistics.

Design & Settings: The category, period, and regions selected in the Google Trends were "health," "15 January-15 May 2020," in the United States of America (USA), the United Kingdom (UK), Germany, Italy, and France, respectively. The most commonly searched herbs, foods and supplements (n = 32) during the pandemic were determined from a pool of keywords (n = 1286) based on the terms' relative search volumes (RSVs) within the last five years.

Synthesis, characterization, crystal structure, α-glycosidase, and acetylcholinesterase inhibitory properties of 1,3-disubstituted benzimidazolium salts.

Chloro-/fluorobenzyl-substituted benzimidazolium salts were synthesized from the reaction of 4-fluorobenzyl/2-chloro-4-fluorobenzyl-substituted benzimidazole and chlorinated aromatic hydrocarbons. They were characterized using various spectroscopic techniques (Fourier-transform infrared and nuclear magnetic resonance) and elemental analysis. In addition, the crystal structures of the complexes 1a -d and 2b were determined by single-crystal X-ray diffraction methods.

Anti-Ulcerogenic and Cytoprotective Effects of Saharian (Sidr) Honey from Algeria.

Aim And Objective: This study aimed at investigating the gastro-protective effects of Algerian Sahara (Sidr) honey from Apis mellifera intermissa against HCl/Ethanol-induced gastric ulcers in rats.

Materials And Methods: Total phenolic content, antioxidant activity and phenolic compounds were determined. Then, three groups of rats (control, HCl/ Ethanol-induced ulcer, and orally administered honey) were used for the determination of gastro-protective effect of Sidr honey.

Increasing suction pressure during endotracheal suctioning increases the volume of suctioned secretions, but not procedure-related complications: A comparative study in open system endotracheal suctioning.

Objectives: To compare the effect of three different suction pressures (80 mmHg, 150 mmHg, 250 mmHg) with the open system suction method in terms of the volume of secretions and complications development in intubated intensive care patients.

Research Methodology/design: This study was planned as a prospective, experimental, self-controlled design. The study sample included 47 patients.

The effects of and gene polymorphisms on warfarin maintenance dose in Turkish cardiac patients.

Our aim was to examine the effect of and polymorphisms on warfarin dose requirements in Turkish patients. 24 warfarin prescribed patients were included and analyzed for eight and 6 polymorphisms in the study. Patients with *1/*1 and -1639 GG and GA genotypes required higher warfarin doses in comparison to wild type genotype.

Evaluation of Cytotoxicity and Mutagenicity of Wastewater from Istanbul: Data from Hospitals and Advanced Wastewater Treatment Plant.

Wastewater (WW) carry considerable amount of chemicals that could have mutagenic or cytotoxic effect from hospital discharges to aquatic environment. Our objective was to determinate the possible mutagenic and toxic effects of hospital originated WWs and effectiveness of the wastewater treatment plants (WTP) functions. In the study the mutagenic and cytotoxic potential of three hospitals and influent/effluent of a treatment plant WW collected in Istanbul and was examined using AMES, XTT, and lactate dehydrogenase (LDH) assays.

Fast off-line FPSE-HPLC-PDA determination of six NSAIDs in saliva samples.

A fast off-line FPSE-HPLC-PDA method has been reported that allows simultaneous clean up and determination of six non-steroidal anti-inflammatory drugs (NSAIDs) in saliva samples from healthy volunteers. Particularly, furprofen, indoprofen, ketoprofen, fenbufen, flurbiprofen, and ibuprofen were chromatographically resolved. Benzyl paraben was chosen as the internal standard (BzPB, IS).

Determination of Chemical Composition and α-amylase Inhibitory Effect of New Propolis Extracts.

Background: Propolis is a resinous mixture collected by honeybees from tree buds and exudates of the plants. Propolis contains aromatic acids, diterpenic acids and phenolic compounds and these components are responsible for its antitumor, anticancer, antiviral and antifungal effects. Propolis can be extracted and the solubility of propolis differs depending on the solvent used in the process of extraction.

Evaluating the Anatomical Traits of Lip on Three-Dimensional Computed Tomography Images.

Background: Lips and mouth are the most recognizable parts of the lower face. The morphometry of the facial organs is important for the balance of the face. Besides congenital anomalies occur on the lips, some kinds of deformities might be seen because of trauma or carcinoma.

Determination of some fluorescence parameters of L sub-shells for Th and U at 59.54 keV photon energy.

The L X-ray fluorescence cross-sections at 59.54 keV, L sub-shell fluorescence and Auger yields, L sub-shell level widths, life times and some selected radiative transfer probabilities of L to M, N and O sub-shells were determined using Energy Dispersive X-ray Fluorescence for Th and U. The experiments were performed with a Si(Li) detector and an Am-241 radioactive annular source in excitation geometry.

An investigation of the relation between catalase gene polymorphism and catalase enzyme activity in leukemia patients.

Introduction: Catalase (CAT), an antioxidant enzyme, catalyzes conversion of hydrogen peroxide to water and molecular oxygen, protecting cells against oxidative stress. The aim of this study was to investigate the possible association between polymorphism in the promoter region of the gene and leukemia risk and to determine the relationship between genotypes and CAT enzyme activities.

Material And Methods: Genotypes of 102 cases and 112 healthy controls' genotypes were determined by polymerase chain reaction-restriction fragment length polymorphism methods.

Bacteroidetes and Firmicutes levels in gut microbiota and effects of hosts TLR2/TLR4 gene expression levels in adult type 1 diabetes patients in Istanbul, Turkey.

Aim: The aim of this study was to determine and compare the levels of both Bacteroidetes and Firmicutes in the gut microbiota and TLR2/TLR4 gene expression in the blood of patients with type 1 diabetes mellitus (T1DM) and healthy individuals. These results may serve as a preliminary assessment to guide future research.

Method: Between January and October 2014, stool and blood samples were collected from 53 adult T1DM patients and 53 age- and gender-matched healthy individuals.

Characterisation of OC125-8 lipase for oily wastewater treatment.

In this study, the lipase-producing bacterium (GenBank number MF621564) was identified, and the extracellular OC125-8 lipase produced by this strain was characterised for use in wastewater treatment. The lipase was partially purified by ammonium sulphate precipitation at a final yield of 3.28-fold purification and a recovery of 56%.

Co-culture of rat luteal cells with islet cells enhances islet viability and revascularization.

Islet cell transplantation is a major treatment strategy for type I diabetes, and has proven to be effective for maintaining glucose homeostasis. However, this treatment requires an extended period of immunosuppression to prevent rejection and recurrent transplantation to maintain function. Thus, to enhance the properties of transplanted islet cells, we examined the effect of the co-culture of luteal cells, which secrete progesterone, on islet cell viability, functionality, and revascularization.

Comparison of two different techniques of cooperative learning approach: Undergraduates' conceptual understanding in the context of hormone biochemistry.

The purpose of the research was to compare the effects of two different techniques of the cooperative learning approach, namely Team-Game Tournament and Jigsaw, on undergraduates' conceptual understanding in a Hormone Biochemistry course. Undergraduates were randomly assigned to Group 1 (N = 23) and Group 2 (N = 29). Instructions were accomplished using Team-Game Tournament in Group 1 and Jigsaw in Group 2.