3D printed PCL-nHAp composite implants for the treatment of segmental bone defects: in vivo application in a rabbit model.

The management and treatment of long bone defects are challenging clinical problems. In this study, in order to address the need for load bearing segmental defects, 3D printed cylindrical implants of poly(-caprolactone) (PCL) and nanohydroxyapatite (nHAp) composites were prepared and applied as lateral segments to the femurs of New Zealand white rabbits. The results obtained after 6 weeks of implantation were compared with the autografts.

The effect of pranic healing based on Rogers' therapeutic touch on cardiorespiratory indices and pain during venipuncture in pediatrics: A randomized clinical trial.

Background: Venipuncture is a commonly performed but distressing procedure for children, often leading to significant pain and anxiety. This study aimed to evaluate the effect of Pranic Healing, based on Rogers' Therapeutic Touch Nursing Theory, on the cardiorespiratory indices and pain associated with venipuncture in children.

Methods: This double-blind, randomized clinical trial was conducted on a cohort of 46 school-aged children, selected via convenience sampling, at a hospital in Northern Cyprus.

An Evaluation of Language Development and Working Memory in Children with Hearing Loss.

Background:  Children with hearing loss (HL) have difficulty in performing the complex functions of language, especially in noisy environments. Cognitive processes such as working memory and short-term memory are effective on individual differences in language skills in children with HL.

Purpose:  The present study aimed to evaluate the vocabulary and syntax skills in language development areas and working memory of children with HL and to compare these results with those of their peers with normal hearing (NH).

Assessment of temporal changes in cognitive effects induced by antiseizure medications in epilepsy patients.

Objective: Numerous studies have been conducted investigating the effects of antiseizure medications (ASMs) on cognitive functions, and the cognitive side effects of some ASMs have been demonstrated. However, data on whether tolerance to these side effects develops over time is insufficient. The aim of this study is to evaluate the reversibility of cognitive impairments caused by ASMs in patients, utilizing event-related potentials (ERPs) and the Montreal Cognitive Assessment (MoCA) test.

The Role of Social Support in Enhancing Life Satisfaction Among Syrian Refugees in Türkiye During the COVID-19 Pandemic.

Purpose: This study investigates the role of perceived social support from family and friends in enhancing life satisfaction among Syrian refugees in Türkiye during the COVID-19 pandemic.

Materials And Methods: A cross-sectional survey was conducted among 636 Syrian refugees residing in Istanbul and Hatay provinces. The study used the Multidimensional Perceived Social Support Scale, the COVID-19 State Anxiety Sources Scale, and the Satisfaction With Life Scale.

The PSR corpus: A Persian sentence reading corpus of eye movements.

The present study introduces the Persian Sentence Reading (PSR) Corpus, aiming to expand empirical data for Persian, an under-investigated language in research on oculomotor control in reading. Reading research has largely focused on Latin script languages with a left-to-right reading direction. However, languages with different reading directions, such as right-to-left and top-to-bottom, and particularly Persian script-based languages like Farsi and Dari, have remained understudied.

Patient satisfaction study for the new Rigicon Infla10 inflatable penile prosthesis including single surgeon safety and outcomes data.

Background: Rigicon is a newer inflatable penile prostheses (IPP) manufacturer that has produced the Infla10 IPP for countries outside the United States (US) since 2019, with Food and Drug Administration studies for approval of Infla10 in the US presently underway.

Aim: This study aims to report the first patient satisfaction, efficacy, and safety from revision data for the newly available Rigicon Infla10 IPP.

Methods: A single surgeon's first 58 patients who underwent Rigicon Infla10 IPP implantation between 2019 and 2023 were included.

First Report of Crown and Root Rot on Eastern Redbud () Caused by in Tennessee.

Eastern redbuds () are the important trees in Tennessee nurseries, known for their vibrant spring blooms, and heart-shaped foliage (Kidwell-Slak and Pooler 2018). In May 2023, container-grown eastern redbuds exhibited crown and root rot symptoms. Disease incidence was 50% of 100 plants and severity was 40% for the affected root area.

First Report of Causing Root Rot on in Tennessee and the United States.

Swamp white oak () is a North American species of medium-sized trees in the beech family. One-year-old swamp white oak seedlings grown in field conditions in a commercial nursery in Warren County, Tennessee exhibited severe root rot in July 2024. Dark brown lesions were observed in the affected roots (Fig.

Evaluation of the mandibular canal and the third mandibular molar relationship by CBCT with a deep learning approach.

Objective: The mandibular canal (MC) houses the inferior alveolar nerve. Extraction of the mandibular third molar (MM3) is a common dental surgery, often complicated by nerve damage. CBCT is the most effective imaging method to assess the relationship between MM3 and MC.

Quality of Life and Related Factors in Patients Diagnosed with Mucopolysaccharidosis and Their Caregivers.

Objectives: Quality of life (QoL) is directly associated with physical-psychological well-being, family and environmental factors in patients with Mucopolysaccharidosis (MPS). The present study aims to investigate the factors affecting QoL in both MPS patients and their caregivers.

Methods: The sociodemographic characteristics, clinical findings, and special needs of 37 patients with MPS were questioned, among which 28 pediatric patients were evaluated for QoL using the KINDL-parents scale.

End-to-end deep learning patient level classification of affected territory of ischemic stroke patients in DW-MRI.

Purpose: To develop an end-to-end DL model for automated classification of affected territory in DWI of stroke patients.

Materials And Methods: In this retrospective multicenter study, brain DWI studies from January 2017 to April 2020 from Center 1, from June 2020 to December 2020 from Center 2, and from November 2019 to April 2020 from Center 3 were included. Four radiologists labeled images into five classes: anterior cerebral artery (ACA), middle cerebral artery (MCA), posterior circulation (PC), and watershed (WS) regions, as well as normal images.

The morphology of the preimaginal stages of Choreutis muhabbet Koçak, 2008 (Choreutidae, Lepidoptera).

This work presents the first description of the last instar larval and pupal morphology of the metalmark moth species Choreutis muhabbet Koçak, 2008. All diagnostic morphological features are described in detail, and illustrated with photographs and line drawings. Diagnostic features for the genus Choreutis (Hübner) based on the described last instar larvae and pupae, are proposed and discussed.

Pro's and con's of different blocks for postoperative analgesia after video-assisted thoracic surgery.

Purpose Of Review: Although there are a lot of studies examining the effects of different blocks for postoperative analgesia after video-assisted thoracic surgery (VATS), the results are controversial.

Recent Findings: Paravertebral block, serratus anterior plane block and erector spinae plane block appear to be effective and beneficial for post-VATS analgesia, but probably in different manners.

Summary: All three blocks can be suggested for daily practice, the choice should be based on personal experience and preference of the anesthetist.

Liver Transplantation for Acute Liver Failure due to Mushroom Poisoning.

Background/aims: Liver transplantation is a life-saving approach in some cases of mushroom poisoning, which is one of the important causes of acute liver failure. However, debate continues regarding the timing of liver transplantation. The aim of this study is to retrospectively evaluate the results of patients who underwent liver transplantation due to mushroom poisoning.

Histopathological Comparison of Various Tongue Base Reduction Processes.

Background And Aim: Tongue base reduction surgery is the only minimally invasive technique that can be performed under local anesthesia as an outpatient procedure, especially to treat obstructive sleep apnea caused by hypopharyngeal obstruction. Studies reported that various devices could be used for tongue base reduction, but comparisons of these methods are limited in the literature. Our study aimed to compare the histological effects of tongue base reduction methods performed with the Celon radiofrequency, monopolar cautery, Coblator, and Sutter devices on the tissue.

Neurohormonal activation pattern in patients with atrial septal defect.

Atrial septal defects (ASD) divert flow from systemic to pulmonary circulation, and some degree of plasma volume expansion and neurohormonal activation are necessary to maintain the effective circulatory volume. The aim of the present study was to understand the patterns of neurohormonal activation in ASD patients. 16 ASD patients and 10 controls were enrolled.

Psychological and Pain Factors in Microsurgical Testicular Sperm Extraction (Micro-TESE) for Non-Obstructive Azoospermia: A Comparative Study of Successful and Unsuccessful Cases.

Purpose: This study aimed to assess postoperative pain, depression, and anxiety levels in infertile men who underwent microsurgical testicular sperm extraction (micro-TESE) for non-obstructive azoospermia (NOA) and compare results between patients with successful and unsuccessful sperm retrieval.

Material And Methods: A total of 105 NOA patients participated, completing preoperative Beck Depression Inventory (BDI) and Situational and Transient Anxiety Inventory (SAI and TAI) questionnaires. Postoperatively, Visual Analog Scale (VAS) scores were recorded.

The Relation of Insulin Resistance With Free Androgen Index and Endothelial Dysfunction Marker YKL-40 and Its Effect on Male Infertility: A Prospective Study.

Purpose: In this study, the effects of insulin resistance and the role of the endothelial dysfunction marker YKL-40 in male infertility were investigated.

Methods: This study was conducted with male patients who underwent fertility investigations in the in vitro fertilization (IVF) unit of a tertiary center. Semen samples were evaluated after two to five days of sexual abstinence.

Systemic Immune Inflammatory Index as Predictor of Blood Pressure Variability in Newly Diagnosed Hypertensive Adults Aged 18-75.

Accumulating evidence from clinical trials, large registries, and meta-analyses of population studies shows that increased Blood Pressure Variability (BPV) is predictive of Cardiovascular (CV) outcomes, independently of the average Blood Pressure (BP) values. One of the mechanisms explaining the relationship between BPV and target organ damage is the inflammatory response. The Systemic Immune Inflammation Index (SII), which relies on peripheral blood cell counts, including platelets, neutrophils, and lymphocytes, has emerged as a predictor of prognosis and outcomes in various diseases.

Magnetic resonance imaging characteristics of ovarian torsion: insights into diagnostic features.

Purpose: We aimed to describe the magnetic resonance imaging (MRI) features of adnexal torsion, additional radiological findings and apparent diffusion coefficient (ADC) measurements of the affected and non-affected ovaries.

Methods: We retrospectively examined the MRI of 34 torsed adnexa of 34 cases. We specifically examined the peripherally displaced follicle sign, stromal edema, lack of stromal contrast enhancement, follicular rim sign, T2 hypointense rim sign, uterine deviation, adnexal displacement, whirlpool sign, T2 hypointense dot sign, and tubal thickening.

Using high-frequency oscillations from brief intraoperative neural recordings to predict the seizure onset zone.

Background: While high-frequency oscillations (HFOs) and their stereotyped clusters (sHFOs) have emerged as potential neuro-biomarkers for the rapid localization of the seizure onset zone (SOZ) in epilepsy, their clinical application is hindered by the challenge of automated elimination of pseudo-HFOs originating from artifacts in heavily corrupted intraoperative neural recordings. This limitation has led to a reliance on semi-automated detectors, coupled with manual visual artifact rejection, impeding the translation of findings into clinical practice.

Methods: In response, we have developed a computational framework that integrates sparse signal processing and ensemble learning to automatically detect genuine HFOs of intracranial EEG data.