The Turkish Version of the Revised Nottingham Sensory Assessment: Validity and Reliability in Chronic Stroke Survivors.

Background: Evaluation of sensory functions in chronic stroke survivors is essential to plan and implement effective treatment and rehabilitation.

Objective: To investigate the validity and reliability of the Turkish version of the Revised Nottingham Sensory Assessment (rNSA-T) in chronic stroke survivors.

Methods: We applied the World Health Organization's translation protocols to develop the rNAS-T.

Comparison of the effect of general anesthesia and combined epidural anesthesia on the anesthetic management of gynecological oncological surgery.

Objective: To evaluate the potential advantages of combined general and epidural anesthesia for major gynecological oncological surgeries.

Materials And Methods: The data of 690 gynecological cancer were retrospectively examined, and 223 patients who met the inclusion criteria were included in the study. The patients were divided into two groups: Group G (123 patients who received general anesthesia only) and Group C (100 patients who received combined epidural and general anesthesia.

The Significance of SARC-F Scores in One-Year Mortality of Adults with High Nutritional Risk with Cancer.

Sarcopenia, being prevalent in up to 70% of cancer patients, is associated with adverse clinical outcomes. The use of the Simple Questionnaire for Rapidly Diagnose of Sarcopenia (SARC-F), a questionnaire developed to screen for sarcopenia, remains to be investigated in cancer patients. The aim in this study was to assess the prognostic value of SARC-F on one-year mortality in cancer patients at high nutritional risk.

Thiol-Disulfide Homeostasis in Noise-Induced Hearing Loss in Rats.

Background: This study was designed to assess if thiol-disulfide homeostasis could be used as diagnostic biomarker in noise-induced hearing loss (NIHL) in a laboratory animal model.

Methods: The study was carried out with a total of 28 female albino rats in 4 groups: group 1 (control group) included rats that were not exposed to noise or any study treatment; in group 2, following noise exposure, rats received 2 mg of dexamethasone per kilogram of body weight via the intramuscular route for 5 days; in Group 3, rats were exposed to noise and received a saline solution for 5 days, in a volume (0.15 cc) matched to that of dexamethasone administered in group 2; and in group 4, rats were exposed to noise, and blood samples were collected during the early phase to assess thiol-disulfide homeostasis without administering any treatment.

A comparison of two surgical techniques for basal cell carcinoma of the eyelid: two-step surgery and one-step surgery.

Objective: To compare the results of one-step surgery (OSS) and two-step surgery (TSS) in the surgical management of eyelid basal cell carcinomas (BCC).

Method: A total of 43 eyes of 43 patients were included. OSS was applied to 22 of these patients, while TSS was applied to 21 patients.

Effect of upper eyelid blepharoplasty with or without orbicularis oculi muscle removal on anterior segment parameters, keratometry, and ocular biometry.

Purpose: To evaluate the effect of upper eyelid blepharoplasty with or without the removal of a strip of orbicularis oculi muscle on corneal topographic parameters, anterior segment parameters, intraocular pressure, and ocular biometry.

Method: This prospective study examined 428 eyes of 214 patients with dermatochalasis. Patients were divided into two groups randomly: those who underwent orbicularis oculi muscle excision (Group 1) during blepharoplasty and those who did not (Group 2).

Hyperandrogenemia impairs endometrial vitamin D receptor expression in polycystic ovary syndrome.

Objectives: To determine the effects of hyperandrogenemia and other phenotypic parameters on endometrial vitamin D receptor (VDR-X2 and VDR-X4) expression in women with polycystic ovary syndrome (PCOS) undergoing ovarian stimulation and total embryo freezing.

Methods: Forty-four PCOS patients were divided into four phenotypes according to the criteria for hyperandrogenemia (HA), ovulatory dysfunction (OD), and polycystic ovary morphology (PCOM): phenotype A (HA+OD+PCOM), phenotype B (HA+OD), phenotype C (HA+PCOM), and phenotype D (OD+PCOM). Endometrial VDR expression was determined by real-time PCR and immunohistochemistry.

An Improvement Project to Lower Pneumothorax Rates in Neonates Born at 36 Weeks' Gestational Age or Beyond.

Objective: Our institutional data revealed high pneumothorax rates in term neonates resuscitated in the delivery room (DR). Other studies have reported that high rates of continuous positive airway pressure (CPAP) in the DR are associated with increased pneumothorax rates. We sought to test the hypothesis that quality improvement efforts to reduce the use of CPAP in the DR would be associated with a reduced incidence of pneumothorax.

Current Developments in the Treatment of Postpartum Depression: Zuranolone.

Pregnancy is a period in a woman's life during which she experiences physiological, psychological, and social changes. These changes can lead to various mental illnesses, including postpartum depression (PPD), which is common during the perinatal period. Postpartum depression is a significant cause of morbidity and mortality for both the mother and baby.

Postoperative Analgesic Efficacy of Clavipectoral Plane Block and Serratus Posterior Superior Intercostal Plane Block Combination in Clavicle Surgeries: A Report of 10 Cases.

This case series included 10 patients who underwent clavicular fracture surgery under general anesthesia. A novel analgesic approach combining 2 distinct nerve block techniques-serratus posterior superior intercostal plane block (SPSIPB) and clavipectoral plane block (CPPB)-was used for postoperative pain management. SPSIPB provided sensory blockade for the innervation of the clavicular skin, whereas CPPB targeted the clavipectoral fascia.

Time-Sensitive Quality Metrics of Acute Stroke Care: A Comprehensive Stroke Center Experience.

The stroke center approach provides an efective solution for acute stroke management. Our study aims to systematically analyze our stroke center records to identify factors that afect acute stroke time-sensitive quality metrics. Data were prospectively collected from 524 acute stroke patients at the Comprehensive Stroke Center of Atatürk UniversityMedical Faculty Hospital between January 1, 2021, and September 30, 2021.

Predictive value of hematologic parameters and HALP score for testicular viability in adults with testicular torsion: A multicentric study.

Objectives: To evaluate the predictivity of haematologic parameters and HALP score on testicular viability in adults with testicular torsion.

Methods: We retrospectively analyzed the clinical data of 139 men ≥18 years of age who underwent testicular detorsion with fixation (n = 90) or orchiectomy (n = 49) due to testicular torsion in five different tertiary centers between May 2019 and August 2023. Demographic, pre-, peri- and postoperative data were analyzed.

Vitrectomy With Short-Term Perfluorocarbon Liquid Tamponade for Retinal Detachment With Inferior Retinal Breaks and Proliferative Vitreoretinopathy.

To assess and compare the results of pars plana vitrectomy (PPV) with short-term perfluorocarbon liquid (PFCL) tamponade and combined PPV with scleral buckling to treat rhegmatogenous retinal detachment (RRD) with inferior retinal breaks complicated by proliferative vitreoretinopathy (PVR). The medical records of patients who had vitreoretinal surgery for RRD with inferior retinal breaks complicated by PVR were reviewed. Group 1 had PPV with PFCL, and Group 2 had PPV with scleral buckling.

LesionScanNet: dual-path convolutional neural network for acute appendicitis diagnosis.

Acute appendicitis is an abrupt inflammation of the appendix, which causes symptoms such as abdominal pain, vomiting, and fever. Computed tomography (CT) is a useful tool in accurate diagnosis of acute appendicitis; however, it causes challenges due to factors such as the anatomical structure of the colon and localization of the appendix in CT images. In this paper, a novel Convolutional Neural Network model, namely, LesionScanNet for the computer-aided detection of acute appendicitis has been proposed.

Influence of sarcopenia as determined by bioelectrical impedance analysis in acute pancreatitis.

Sarcopenia can be defined as the loss of muscle mass and strength. It is a poor prognostic factor for many diseases. Our study aims to assess the prevalence of sarcopenia in patients with acute pancreatitis using bioelectrical impedance analysis (BIA) and hand dynamometry while also investigating its impact on acute pancreatitis.

Serum Biomarkers IL-6 and HIF-1α in Rosacea: Assessing Their Significance in Disease Pathogenesis and Telangiectasia Formation.

Introduction: Rosacea, a chronic inflammatory disease primarily affecting the central area of the face, is a complex condition whose mechanisms are still not fully understood. However, research has indicated a positive correlation between two molecules: hypoxia-inducible factor-1α (HIF-1α) and interleukin-6 (IL-6). The levels of HIF-1α in rosacea patients have yet to be assessed.

Is Unilateral Extended Pterional Craniotomy Preferable Over Bicoronal (Bifrontal) Craniotomy in Large or Giant Olfactory Groove Meningiomas?

Aim: Bicoronal incision and bifrontal craniotomy are commonly used for resecting large (4-6 cm) or giant ( 6cm) olfactory groove meningiomas (OGMs). Although the bifrontal approach provides good bilateral visual access to the anterior cranial fossa, it is associated with the risk of injury to the frontal bridging veins and superior sagittal sinus, infection, and CSF leakage due to the frontal sinus neighborhood.

Material And Methods: This was a retrospective review of 16patients (nine men and seven women) with large and giant OGMs operated through unilateral extended pterional craniotomy between 2010 and 2022.

Documentation of the current state of cardiopulmonary bypass management in Türkiye.

Since the first successful use of cardiopulmonary bypass (CPB), much has changed in its technology, area of use, and management. Despite suggestions in guidelines, the institutional behavior may change based on institutional experience and established habits. This so-called "deviation" may alter management strategies in favorable or unfavorable ways.

Can some inflammatory parameters predict the survival of patients with malignant pleural effusion?

Background: This study aimed to investigate whether there is a correlation between some serum inflammatory markers and the survival of patients with malignant pleural effusions (MPEs).

Methods: The prospective study included 125 patients (67 males, 58 females; median age: 62 years; range, 40 to 92 years) who underwent thoracentesis for pleural effusion between January 2020 and December 2021. An overall survival analysis was performed, and survival differences between the groups were investigated.

Postoperative physical activity limitations and balance changes on patients who have been operated for breast cancer.

Objective: The purpose of this study is to assess the postoperative physical activity limitations and balance changes in patients who have been operated on for breast cancer. Some physical activity limitations and balance disorders can be expected after breast cancer surgery.

Methods: From 2008 to 2016, 112 patients who underwent breast cancer surgery were included in this study.

Evaluation of corporate experiences during the accreditation process in the field of health - A qualitative study.

Objective: In our study, we attempted to determine the accreditation process experience of hospital senior managers accredited by the Turkish Health Care Quality and Accreditation Institute (TUSKA). Along with the institutions' accomplishments through the accreditation program, the major challenges they faced during the accreditation process were revealed.

Methods: One of the qualitative research designs used was interpretive phenomenological analysis, which was carried out through semi-structured interviews with hospital senior managers.

Brexpiprazole for the Treatment of Agitation in Alzheimer's Disease Dementia: Clinical Uncertainties and the Path Forward.

Brexpirazole was approved for the treatment of nonpsychotic agitation in Alzheimer's disease (AD) dementia by the United States Food and Drug Administration (FDA) in May 2023 after three phase 3 clinical trials found brexpiprazole 2 to 3 mg/day to be an effective and well-tolerated treatment for agitation in AD dementia, albeit with small effect sizes. It appeared to especially benefit dementia patients with severe agitation/aggression, but it took between 6 and 12 weeks across the three studies for the medication to separate from placebo. However, much remains unknown about its place in the psychopharmacological armamentarium for the treatment of AD dementia-related agitation, including the optimal duration of a brexpiprazole trial, bridging options during the time it takes for brexpiprazole to become effective, and whether it should be continued in the presence of or upon emergence of psychosis during treatment.

Gut microbiota profiles of patients with idiopathic pulmonary fibrosis.

: Idiopathic pulmonary fibrosis (IPF) is the most common idiopathic interstitial pneumonia. Multiple genetic factors, environmental exposures, micro-aspirations secondary to gastroesophageal reflux, age, sex, smoking habit, and infections contribute to its etiology; consequently, its pathogenesis remains unclear. The homeostasis of gut microbiota, including bacteria, archaea, and fungi, can influence the functions of both the intestine and remote organs.

Comparison of Ultrasound-Guided Hydrodissection with Various Volumes of 5% Dextrose for Carpal Tunnel Syndrome: A Prospective Randomized Controlled Double-Blind Trial.

Objective: Ideal volume of 5% dextrose (D5W) for median nerve hydrodissection (HD) for treating carpal tunnel syndrome (CTS) is still unknown. This study assessed the efficacy of nerve hydrodissection using varying volumes of D5W for treating mild to moderate CTS.

Design: Eighty participants with unilateral mild to moderate CTS were randomized into groups to receive either 5 ml of normal saline (NS), 5 ml of D5W, 10 ml of NS, and 10 ml of D5W, with each group undergoing one session of ultrasound-guided HD.

Septic Arthritis of the Temporomandibular Joint in a Geriatric Patient: A Case Report.

Septic arthritis of the temporomandibular joint is a rare pathology. There is no consensus in the literature regarding etiopathogenesis and treatment. Pain, swelling, trismus, and mandibular deviation are common.