26 results match your criteria: "Asymmetric Periflexural Exanthem of Childhood"

Unilateral laterothoracic exanthema (ULE) is a benign self-limited condition that spontaneously resolves in a few weeks. Occurring mostly in childhood, although few rare cases in adults have been also reported. Diagnosis of ULE is clinical, and laboratory investigations are not required.

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Article Synopsis
  • The asymmetric periflexural exanthema of childhood is a rare skin condition primarily affecting girls around the age of two, characterized by one-sided eruptions that resolve on their own.
  • The condition presents as a papular rash that starts near an axilla or extremity and spreads to the corresponding side of the body without other symptoms.
  • Two cases were reported, both involving young girls who experienced these distinctive rashes and were diagnosed accordingly, with treatments focusing on symptom relief and observing the condition's natural resolution.
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Article Synopsis
  • APEC is a childhood skin condition that causes a one-sided rash and usually resolves on its own.
  • The cause of APEC is not clearly understood, but it is believed to be linked to a viral infection.
  • A report describes a case of a 2-year-old girl with APEC that was associated with influenza A, suggesting a potential viral cause for the condition.
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Article Synopsis
  • The text discusses various skin rashes linked to viral infections, highlighting notable syndromes like pityriasis rosea (PR), Gianotti-Crosti syndrome (GCS), and others, including a newly identified rash called eruptive hypomelanosis (EH).
  • A systematic review of studies over the last 60 years was conducted to analyze epidemiological data and assess whether these rashes are caused by infectious agents, leading to the selection of numerous relevant articles.
  • The findings suggest moderate support for PR, GCS, and asymmetric periflexural exanthem (APE) being linked to infectious causes, while the evidence for the other conditions, including EH, is considered inadequate, indicating potential for future research.
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Superimposed lateralized exanthem of childhood: report of a case related to adenovirus infection.

Clin Exp Dermatol

April 2014

Department of Dermatology and Allergology, Ludwig-Maximilian University, Munich, Germany; Landeshauptstadt München, Referat für Gesundheit und Umwelt, Munich, Germany.

Article Synopsis
  • A 6-year-old boy experienced an itchy rash that started on one side of his body before spreading to both sides, but it healed on its own within four weeks.
  • The rash was linked to a respiratory adenovirus infection, and it has several names, including 'unilateral laterothoracic exanthem' and 'asymmetrical periflexural exanthem of childhood.'
  • A new term, 'superimposed lateralized exanthem of childhood,' suggests that a genetic mutation may make one side of the skin more sensitive to infections, leading to the initial unilateral rash and a milder response on the other side.
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Article Synopsis
  • A 4-year-old boy experienced a temporary eczema-like rash primarily on the left side of his trunk and limbs, clearly separated by the midline.
  • The rash began resolving on its own within 4 weeks, leaving no lasting effects.
  • The doctors speculate that this condition may have been either unilateral blaschkitis or asymmetric periflexural exanthem.
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Left-sided eruption on a child: case study.

Dermatol Nurs

August 2007

Ronald O. Perelman Department of Dermatology, Dermatologic and Laser Surgery, Mohs Micrographic Surgery, New York University School of Medicine, New York, NY, USA.

Article Synopsis
  • - Asymmetric periflexural exanthema of childhood is a non-serious condition that typically resolves on its own and has an unknown cause.
  • - It usually appears after a few weeks of symptoms resembling a viral infection, featuring red spots and bumps in the skin's folds, which then spread outward.
  • - The main goal of treatment is to relieve itching associated with the rash.
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Asymmetric periflexural exanthema: a report in an adult patient.

Indian J Dermatol Venereol Leprol

July 2007

Skin Disease Centre, Shreeram Sankul, Opp. Hotel Panchavati, Vakilwadi, Nashik-422 002.

Article Synopsis
  • Asymmetric periflexural exanthem (APE) is a unique skin rash, likely caused by a virus, primarily seen in children.
  • It's rare for adults to develop this condition.
  • The report discusses an adult male who exhibited the classic symptoms associated with APE.
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Viral exanthems in the tropics.

Clin Dermatol

June 2007

Sector of Dermatology, School of Medicine and HUCFF-UFRJ, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

Article Synopsis
  • Viral exanthems are common in tropical areas, especially among children, and most are harmless but some can be severe.* -
  • Pregnant women and vulnerable infants are at the highest risk for serious complications from these infections.* -
  • The article covers various viruses linked to exanthems, including parvovirus B19, dengue, yellow fever, and Ebola, among others.*
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Asymmetric periflexural exanthem of childhood: microbiologic case-control study.

Pediatr Dermatol

September 2000

Unité de Dermatologie Pédiatrique, Hôpital Pellegrin-Bordeaux, Bordeaux, France.

Article Synopsis
  • This study aimed to investigate potential causes of asymmetrical periflexural exanthem of childhood (APEC) by examining various microbiological agents through a case-control approach.
  • Researchers analyzed samples from 37 children with APEC and 37 age-matched controls but found no significant differences in the presence of viruses or bacteria between the two groups.
  • The results suggested that APEC is not triggered by common microbiological agents, indicating the need for more advanced methods to explore its underlying causes.
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[Asymmetric periflexural exanthema of childhood].

Ugeskr Laeger

April 2000

Odense Universitetshospital, dermato-venerologisk afdeling I.

Article Synopsis
  • Asymmetric peri-flexural exanthem of childhood is a newly identified disease that has not previously been documented by Danish researchers.
  • It typically presents as an asymmetric maculopapular rash that starts on one side of the body near the armpit before spreading outward over the course of a week.
  • The rash usually resolves on its own within four to six weeks, and the article describes two cases of this condition.
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Asymmetric periflexural exanthem of childhood: a clinical, pathologic, and epidemiologic prospective study.

Arch Dermatol

July 1999

Unité de Dermatologie Pédiatrique, Hôpital Pellegrin-Enfants, Bordeaux, France.

Objective: To assess the clinical, pathologic, and epidemiologic features of asymmetric periflexural exanthem of childhood (APEC), a clinically distinctive eruption, especially its link with pityriasis rosea and pattern of transmission.

Design: A prospective case series, including an analysis of epidemiologic triggering factors and mode of transmission. Pathologic study, including immunohistochemistry of the inflammatory infiltrate.

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Childhood exanthems.

Curr Opin Pediatr

August 1995

University of California at San Francisco, Department of Dermatology 94143, USA.

Article Synopsis
  • Childhood exanthems are common skin diseases in kids, with several new findings discussed in relation to them.
  • Conditions like unilateral laterothoracic exanthem and asymmetric periflexural exanthem might be variations of the same illness, possibly linked to different infections.
  • New information on papular-purpuric gloves and socks syndrome, and eruptive pseudoangiomatosis is presented, along with updates on exanthem subitum's causes and disease range.
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Article Synopsis
  • Researchers studied 187 children (111 girls, 76 boys) over four years who presented with a unique skin rash during winter and spring.
  • The rash started on the trunk or limb flexures, spreading outward over two to four weeks, and eventually faded with minor itching and skin peeling.
  • Virology tests in 34 cases found a slight link between viral infections (like parainfluenza and adenovirus) and skin symptoms, suggesting the two may be unrelated.
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Asymmetric periflexural exanthem of childhood: report of two new cases.

Pediatr Dermatol

March 1994

Institute for Dermatological Sciences, University of Milan, IRCCS, Ospedale Maggiore, Italy.

Article Synopsis
  • A newly identified skin rash in infants appears as an eczematous or scarlet-fever-like eruption, starting from one armpit and spreading outward on the same side of the body.
  • It can be slightly itchy and sometimes comes with swollen lymph nodes nearby, although lesions are rarely found on the opposite side.
  • The rash tends to occur in small outbreaks, suggesting that a viral infection may be responsible, and the authors report two additional cases, indicating that this condition is more common than previously thought.
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