1 results match your criteria: "Associated Unit R+D+i Institute of Medicinal Chemistry (IQM-CSIC)-URJC[Affiliation]"
Systematic Review and Metanalysis of the Expression of Blood-Based and Cerebrospinal Fluid-Based Biomarkers Related to Inflammatory Mediators in Neuropathic Pain.
J Integr Neurosci
June 2024
Area of Pharmacology and Nutrition and Bromatology, Department of Basic Health Sciences, School of Health Sciences, Universidad Rey Juan Carlos, High Performance Experimental Pharmacology Research Group, Universidad Rey Juan Carlos (PHARMAKOM), Associated Unit R+D+i Institute of Medicinal Chemistry (IQM-CSIC)-URJC, 28922 Alcorcón, Spain.
Article Synopsis
- - The review aims to explore potential biomarkers in blood and cerebrospinal fluid for diagnosing and treating neuropathic pain, given the incomplete understanding of this condition.
- - A systematic search of six research databases led to analyzing 16 studies, revealing no significant differences in inflammatory biomarkers (CRP, IL-6, TNF-alpha) between patients with neuropathic pain and those without.
- - Results highlight the complexity of neuropathic pain, showing methodological strengths but limited by publication bias and variability in study findings, indicating the necessity for further research to identify reliable biomarkers.