2,061 results match your criteria: "Assisted Ventilation of the Newborn"
Pediatr Int
December 2024
Department of Pediatrics, Korea University Anam Hospital, Seoul, South Korea.
Background: Evidence to show that neurally adjusted ventilatory assist (NAVA) improves clinical outcomes is lacking. We aimed to analyze whether NAVA improves respiratory outcomes in preterm infants who require invasive mechanical ventilation.
Methods: A retrospective cohort study was conducted in 122 very low birthweight infants who required invasive mechanical ventilation for more than 24 h at one tertiary neonatal intensive care unit in Korea from January 2016 to June 2023.
J Med Econ
December 2025
Novartis Gene Therapies Switzerland GmbH, Rotkreuz, Switzerland.
Aims: Spinal muscular atrophy (SMA) is a rare genetic disorder characterized by progressive muscle weakness, atrophy, respiratory failure, and in severe cases, infantile death. Early detection and treatment before symptom onset may substantially improve outcomes, allowing patients to achieve age-appropriate motor milestones and longer survival. We assessed the cost-utility of newborn screening (NBS) for SMA in Japan.
View Article and Find Full Text PDFJ Cachexia Sarcopenia Muscle
December 2024
Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Center for Musculoskeletal Surgery, Berlin, Germany.
Eur J Pediatr
November 2024
Department of Neonatal Medicine of Port Royal, Cochin Hospital, FHU PREMA, AP-HP Centre, Université Paris Cité, Paris, France.
Unlabelled: The short-term respiratory consequences of small for gestational (SGA) are only partially known. Our aim was to compare the early respiratory features between SGA and appropriate for gestational age (AGA) in very preterm infants. We conducted a secondary analysis of the French prospective EPIPAGE-2 cohort.
View Article and Find Full Text PDFInt J Environ Res Public Health
October 2024
College of Medicine, Central Michigan University, Mt. Pleasant, MI 48859, USA.
The harms of combustible cigarette (CC) use in pregnancy for fetal development are well studied. Less understood are the potential impacts of newer non-combustible cigarette alternatives, including electronic cigarettes (ECs). Our goal was to examine whether EC use during pregnancy predicts increased risk of adverse birth outcomes.
View Article and Find Full Text PDFZhongguo Dang Dai Er Ke Za Zhi
November 2024
Center for Newborn Care, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, China.
Scand J Trauma Resusc Emerg Med
November 2024
Department of Emergency Medicine and Pre-Hospital Services, St. Olav's University Hospital, Trondheim, Norway.
Background: Pre-hospital incidents involving pediatric and neonatal patients are infrequent, and clinical characteristics and care for these patients differ from the adult population. Lack of knowledge, guidelines, and experience can make pre-hospital pediatric care challenging, and there is limited research on the epidemiology and best practice of care for this population. We examined the pre-hospital pediatric population in the county of Sør-Trøndelag, Norway, to improve our understanding of this population in our region.
View Article and Find Full Text PDFChildren (Basel)
September 2024
Division of Newborn Medicine, Maria Fareri Children's Hospital, Westchester Medical Center and New York Medical Center, Valhalla, NY 10595, USA.
Eur J Cardiothorac Surg
November 2024
Department of Cardiovascular and Thoracic Surgery, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Objectives: The study's primary outcome was to evaluate if post-transplant survival has improved over the last 2 decades. Secondary outcomes were the infant's waitlist mortality, waitlist time and identifying factors that affected the infant's survival.
Methods: United Network for Organ Sharing (UNOS) database was queried for infants (age ≤ 1) who were listed for heart transplantation between 2000 and 2020.
Pediatr Res
October 2024
Department of Physiotherapy and faculty member of the Graduate Program in Physiotherapy - Santa Catarina State University, Florianópolis, Santa Catarina, Brazil.
Background: Given the knowledge of the damage caused by prolonged invasive mechanical ventilation in premature newborns, withdrawing this support as quickly as possible is important to minimize morbidity. The aim of this study was to analyze the variables associated with extubation outcomes and to develop a predictive model for successful extubation in premature newborns.
Methods: Data were obtained from a multicenter study involving six public maternity hospitals.
Semin Perinatol
December 2024
Professor of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.
J Matern Fetal Neonatal Med
December 2024
Graduate School of Nursing Sciences, Global Health Nursing, St Luke's International University, Tokyo, Japan.
Background: Noninvasive neurally-adjusted ventilatory assist (NIV-NAVA) improves patient-ventilator synchrony and may reduce treatment failure in preterm infants compared with nasal continuous positive airway pressure (NCPAP) and noninvasive positive-pressure ventilation (NIPPV). We conducted a systematic review and meta-analysis to assess the effects of NIV-NAVA in preterm infants with respiratory distress.
Methods: Four investigators independently assessed the eligibility of studies in CENTRAL, CINAHL, ClinicalTrials.
World J Pediatr Congenit Heart Surg
November 2024
The Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Int J Environ Res Public Health
August 2024
Nursing Graduate School, Universidade Federal do Piauí, Teresina 64049-550, Brazil.
Context: The Qualineo Strategy is an effective measure for reducing neonatal mortality in regions with the highest death rates. In addition, it is a relevant Brazilian tool for strengthening teamwork and neonatal assistance. This study aims to analyze the predictors of neonatal death in the indicators of care provided by the Qualineo Strategy at a reference maternity hospital in Piauí, in the years 2021 to 2022.
View Article and Find Full Text PDFNeonatology
October 2024
Centre for Perinatal Research, School of Medicine, University of Nottingham, Nottingham, UK.
Background: Guidelines recommend non-invasive ventilatory (NIV) support as first-line respiratory support mode in preterm infants as NIV is superior to intubation and mechanical ventilation in preventing death or bronchopulmonary dysplasia. However, with an ever-expanding variety of NIV modes available, there is much debate about which NIV modality should ideally be used, how, and when. The aims of this work were to summarise the evidence on different NIV modalities for both primary and secondary respiratory support: nCPAP, nasal high-flow therapy (nHFT), and nasal intermittent positive airway pressure ventilation (nIPPV), bi-level positive airway pressure (BiPAP), nasal high-frequency oscillatory ventilation (nHFOV), and nasally applied, non-invasive neurally adjusted ventilatory assist (NIV-NAVA) modes, with particular focus on their use in preterm infants.
View Article and Find Full Text PDFRes Vet Sci
October 2024
Department of Animal Reproduction, School of Veterinary Medicine and Animal Science, University of São Paulo, Rua Prof. Orlando Marques de Paiva, 87 - Cidade Universitária, São Paulo, SP 05508-270, Brazil. Electronic address:
In premature births, deficiency and/or inactivation of surfactant and incomplete development of lung occur, leading to pulmonary complications and greater need for ventilatory interventions. Prenatal corticosteroid therapy is used to improve neonatal lung function and, thus, may reduce mortality and lower incidence and severity of lung injury. Therefore, this study aimed to assess the need for ventilatory support in preterm lambs subjected or not to prenatal betamethasone treatment, and to evaluate the effectiveness on neonatal survival.
View Article and Find Full Text PDFCurr HIV Res
October 2024
Reproductive Health, Maternal, Fetal and Neonatal Research Center, Institute of Family Health, Tehran University of Medical Sciences, Tehran, Iran.
Background: Pregnancy among women infected with HIV is classified as a high-risk pregnancy. While previous research has indicated an elevated likelihood of preterm birth, low birth weight, and early gestational age in infants born to mothers with HIV, the correlation between maternal HIV infection and different neonatal results remains unclear.
Objective: This study aims to investigate the impact of maternal HIV infection on after-birth neonatal outcomes using machine learning (ML) and statistical methods.
J Epidemiol Community Health
October 2024
Department of Epidemiology, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China
Background: The association of maternal cigarette smoking during pregnancy with severe neonatal morbidity (SNM) is still inconclusive. We aimed to examine the associations of the timing and the intensity of maternal cigarette smoking with infant SNM in the USA.
Methods: We used birth certificate data of 12 150 535 women aged 18-49 years who had live singleton births from the 2016-2019 US National Vital Statistics System.
Vox Sang
November 2024
Pediatric Critical Care, Neonatal Medicine and Emergency, AP-HP Paris Saclay University, Bicêtre Hospital, Le Kremlin-Bicêtre, France.
BMC Pediatr
August 2024
University of New South Wales, Sydney, NSW, 2032, Australia.
Background: Preterm infants often require non-invasive breathing support while their lungs and control of respiration are still developing. Non-invasive neurally adjusted ventilatory assist (NIV-NAVA) is an emerging technology that allows infants to breathe spontaneously while receiving support breaths proportional to their effort. This study describes the first Australian Neonatal Intensive Care Unit (NICU) experience of NIV-NAVA.
View Article and Find Full Text PDFAndes Pediatr
June 2024
Universidad de Chile, Santiago, Chile.
Unlabelled: Congenital Central Hypoventilation Syndrome (CCHS) is a rare genetic condition affecting the autonomic nervous system and respiratory center due to mutations in the PHOX2B gene, and it is associated with alveolar hypoventilation during sleep and sudden death. It requires early invasive mechanical ventilation (IMV).
Objective: To report a neonatal case successfully treated with non-invasive ventilatory support (NVS), avoiding tracheostomy.
Background: Extremely preterm infants (EPIs) frequently encounter challenges in feeding due to their underdeveloped digestive systems. Attaining full enteral feeding at the earliest possible stage can facilitate the removal of vascular catheters and decrease catheter-related complications.
Methods: We performed a retrospective cohort study comprising 145 extremely preterm infants with a gestational age < 28 weeks who underwent non-invasive mechanical ventilation at Shenzhen Maternity & Child Healthcare Hospital between January 2019 and June 2020.
Front Pediatr
July 2024
Servicio de Neonatología, Hospital Universitario 12 de Octubre, Madrid, Spain.
Games Health J
December 2024
Centro di Formazione e Simulazione Neonatale "NINA", U.O. Neonatologia, Dipartimento Materno-Infantile, AOUP, Pisa, Italy.
Pediatr Pulmonol
December 2024
Division of Paediatric Respiratory Medicine and Allergology, Department of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Introduction: Major methodological issues with the existing algorithm (WBreath) used for the analysis of speed-of-sound-based infant sulfur hexafluoride (SF) multiple-breath washout (MBW) measurements lead to implausible results and complicate the comparison between different age groups and centers.
Methods: We developed OASIS-a novel algorithm to analyze speed-of-sound-based infant SF MBW measurements. This algorithm uses known context of the measurements to replace the dependence of WBreath on model input parameters.