Development of Mobile Application Based System for Improving Population Based Cancer Screening by Community Health Workers.

Objective: Cancer remains a leading cause of morbidity and mortality globally, with India experiencing a significant cancer burden. Effective population-based cancer screening is crucial for early detection and reduction of cancer-related deaths. This study aims to develop a mobile application-based Cancer Screening and Surveillance System (CSMS) to enhance the efficiency and effectiveness of population-based cancer screening by community health workers (CHWs).

Seasonal trends and sources of dicarboxylic acids in fine aerosol over the Brahmaputra valley, North-East India.

The atmospheric dicarboxylic acids (DCAs) have a significant impact on the climate and indirectly affect human health, making them important organic substances. PM bound DCAs were analysed for Jorhat, India, 2019. In addition to the temporal variability, seasonal variation throughout the year and the impact of varying meteorological factors on DCAs concentration have also been studied.

Substituent effect in protein binding, optical, electrochemical, and antimicrobial properties of dipyrazinylpyridine ligands.

A series of 2,6-di(pyrazine-2-yl)pyridine (dppy) ligands - of varying substituents of different electronic nature (-NMe, -OMe,-Me, and -Cl) in the 4-position of the pyridine moiety has been designed and synthesized to study the binding behavior of the dppy ligands towards Bovine Serum Albumin (BSA), a low-cost serum albumin protein. The interaction between ligands and BSA has been studied using UV-Visible and fluorescence spectroscopy and molecular docking studies. The fluorescence of BSA was found to be quenched in the presence of all the ligands , in which ligand , having the most electron donating group NMe exhibits the maximum binding affinity towards BSA.

Evaluation of the Efficiency of Ultrasonography and Color Doppler in Diagnosis of Intraosseous Jaw Lesions: An Study.

Aim: The current investigation aimed to evaluate the accuracy of ultrasonography and color Doppler performed in the diagnosis of intraosseous jaw lesions.

Materials And Methods: A total of 30 patients with intraosseous jaw lesions between the ages of 12 and 60 were selected for the present study. For every jaw lesion, a preliminary diagnosis was done using preoperative conventional radiographs.

Morphological Abnormalities Classification of Red Blood Cells Using Fusion Method on Imbalance Datasets.

Red blood cells (RBCs) or Erythrocytes are essential components of the human body and they transport oxygen from the lungs to the body's tissues, regulate balance, and support the immune system. Abnormalities in RBC shapes (Poikilocytosis) and sizes (Anisocytosis) can impede oxygen-carrying capacity, leading to conditions such as anemia, thalassemia, McLeod Syndrome, liver disease, and so on. Hematologists typically spend considerable time manually examining RBC's shapes and sizes using a microscope and it is time-consuming.

Controlling spiral wave dynamics of the BZ system in a modified Oregonator model: From suppression to turbulence.

Spirals are a special class of excitable waves that have its significance in the understanding of cardiac arrests and neuronal transduction. In a theoretical model of the chemical Belousov-Zhabotinsky reaction system, we explore the dynamics of the spatiotemporal patterns that emerge out of competing reaction and diffusion phenomena. By modifying the existing mathematical models of the reaction kinetics, we have been able to explore the explicit effect of hydrogen ion concentration in the system, so as to achieve various regimes of wave activity, from stable spirals to oscillation death.

Phytoplankton-environment dynamics in a tropical estuary of the northeastern Arabian Sea: a Generalized Additive Model (GAM) approach.

Phytoplankton are diverse photosynthetic organisms in estuarine ecosystems and sensitive indicators of environmental changes. This study employed Generalized Additive Model (GAM) to explore the impact of environmental variables on the abundance of six dominant phytoplankton species in the tropical Karanja estuary, India. Data were collected from five sampling stations between January 2022 and March 2023.

Fullerene (C & C)-Meso-Tris-4-Carboxyphenyl Porphyrin Dyads Inhibit Entry of Wild-Type and Drug-Resistant HIV-1 Clades B and C.

The biological applications of noncationic porphyrin-fullerene (P-F) dyads as anti-HIV agents have been limited despite the established use of several cationic P-F dyads as anti-cancer photodynamic therapy (PDT) agents. This article explores the potential of amphiphilic non-cationic porphyrin-fullerene dyads as HIV-1 inhibitors under both PDT (light-treated) and non-PDT (dark) conditions. The amphiphilic P-F dyads, PBC and PBC, demonstrated enhanced efficacy in inhibiting the entry and production of HIV-1 (subtypes B and C).

Edible flowers' flavor, safety and their utilization as functional ingredients: a review.

Edible flowers have been a part of various traditional dishes around the world. The consumption of edible flowers has been rising due to their nutritional properties, minerals, antioxidants, phenolic and bioactive compounds, therapeutic properties, and also aesthetic appeal. Along with the nutrients, some antinutrients and other chemical, biological, microbial hazards may render flowers non-edible.

Sociodemographic and clinical profiles of individuals with opioid dependence syndrome presenting to a tertiary care center in Assam: A retrospective review.

Background: Opioid dependence is a critical public health issue in Northeast India, with limited data available on the affected population.

Aim: This study examines the sociodemographic and clinical profiles of opioid-dependent individuals in Assam.

Methods: A retrospective review was conducted of 238 patients diagnosed with opioid dependence at a tertiary care addiction treatment center in Assam, covering records from January 2022 to January 2023.

Fixed points of two interpolative cyclic contractions in -metric spaces.

The -metric space happens to be one of the of most significant and non-trivial generalizations of metric spaces. In this paper, we introduce the concepts of Kannan type and Ćirić-Reich-Rus type cyclic contractions in -metric spaces via interpolation. Existence and uniqueness of fixed points of these two newly introduced contraction mappings have been studied and validated with suitable examples.

Does women empowerment impact child well-being? Evidence from India.

This study intends to examine how women's empowerment directly or indirectly impacts their children's well-being. Since prior research primarily focussed on the effects of maternal empowerment on specific domains of child well-being, such as healthcare or education, this study seeks to explore a more comprehensive understanding of child well-being, where child well-being is quantified using four domains, viz., physical well-being, psycho-social well-being, educational well-being and awareness of safety.

Welding, Joining, and Additive Manufacturing: Experiments, Materials, and Modeling.

With the advancement of technologies, welding and joining have become an integral part of advanced manufacturing systems [...

Critical Perspectives on Global Health Policy, Diagnostic Access and Practice Gaps towards a Tuberculosis Free India.

Tuberculosis (TB) poses a significant public health challenge in India. According to the World Health Organization (WHO), India tops the list of 30 countries responsible for 87% of global TB cases in 2023. Recent data indicates that India's TB incidence rate was 195 cases per 100,000 population in 2023, accounting for approximately 26% of global TB cases.

Integrated biorefinery approach for sustainable production of biodiesel, bioplastics and high value bioproducts from a bloom forming alga, Botryococcus braunii.

The global shift towards sustainable energy and bioproducts has intensified research on algae. Renewable green biofuel can address and provide solutions to both energy crisis and climate change challenges. Botryococcus braunii, a bloom forming green microalga, known for its high lipid content and potential for biofuel production has been explored in the present study.

Consensus Based Indian Guidelines for the Management of Pemphigus Vulgaris and Pemphigus Foliaceous.

Pemphigus is an autoimmune blistering disorder characterized by the presence of intraepidermal blisters and erosions, primarily affecting the mucosa and/or skin. There are no established Indian guidelines for the management of pemphigus, and Western guidelines cannot be directly applied due to differences in clinicodemographic profiles, comorbidities, and resource limitations. These guidelines aim to provide Indian dermatologists with evidence-based and consensus-driven recommendations for the management of pemphigus vulgaris (PV) and pemphigus foliaceous (PF), taking into account the unique challenges posed by the Indian healthcare setting.

Effects of Substituting Soybean Meal With Winged Bean on Growth, Physiological Function and Flesh Quality of Indian Butter Catfish ().

Soybean meal (SBM) remains a primary protein source in aquafeeds. This study investigated the potential of winged bean () meal as a SBM replacement in diets for butter catfish () juveniles (mean weight: 1.24 ± 0.

Physico-chemical, nutritional, and anti-inflammatory properties of processed Garcinia pedunculata fruit: A combined in vitro and in silico approach.

This study aimed to evaluate the physico-chemical, nutritional, antioxidant, and anti-inflammatory properties of Garcinia pedunculata fruit powders obtained from different drying methods to explore their potential use in health-promoting functional foods. The fruits were processed at mature and ripe stages. Molecular modeling studies were also performed to find effective inhibitors from G.

Classifying tumour infiltrating lymphocytes in oral squamous cell carcinoma histopathology using joint learning framework.

Oral squamous cell carcinoma (OSCC) is the most common form of oral cancer, with increasing global incidence and have poor prognosis. Tumour-infiltrating lymphocytes (TILs) are recognized as a key prognostic indicator and play a vital role in OSCC grading. However, current methods for TILs quantification are based on subjective visual assessments, leading to inter-observer variability and inconsistent diagnostic reproducibility.

Functional genomic insights into Floricoccus penangensis ML061-4 isolated from leaf surface of Assam tea.

Floricoccus penangensis ML061-4 was originally isolated from the leaf surface of an Assam tea plant (Camellia sinensis var. assamica) from Northern Thailand. To assess the functions encoded by the F.

Adsorption of emerging pollutants utilizing chitosan derivatives: Recent advances and future perspective.

Globalization resulted in technological advancement, and urban population growth. Consequently, pollution emerged as an imminent risk to the survival of all species on Earth. Consequently, on a worldwide basis, sustainability become a major issue for legislators.

Unraveling the nutritional potential of millet by-products through extraction of high value compounds for the development of novel food products.

Millets are drought-resistant crops that generate significant amount of by-products (bran, husk, stalk etc.) during harvesting and processing. These by-products are storehouse of nutrients and high value compounds including polyphenols, dietary fiber, proteins etc.

Role of micronutrients in production and reproduction of farm animals under climate change scenario.

Climate change poses significant challenges to livestock production worldwide. Wherein, it affects communities in developing nations primarily dependent on agriculture and animal husbandry. Its direct and indirect deleterious effects on agriculture and animal husbandry includes aberrant changes in weather patterns resulting in disturbed homeorhetic mechanism of livestock vis a vis indirectly affecting nutrient composition of feed and fodder.