80 results match your criteria: "Asokoro District Hospital[Affiliation]"

Background: Tuberculosis (TB), caused by Mycobacterium tuberculosis, is a leading cause of infection-related deaths worldwide. Children with underdeveloped immune systems are particularly vulnerable, experiencing symptoms akin to common childhood illnesses. Early diagnosis and treatment typically yield positive outcomes.

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A review of the association between in vitro fertilization and children's neurocognitive development.

J Assist Reprod Genet

December 2024

Department of Pharmacology, Therapeutics and Toxicology, Faculty of Basic Medical Sciences, University of Lagos, Lagos, Nigeria.

This review investigated the current research on the association between in vitro fertilization and children's neurocognitive development. Twenty studies were analyzed, encompassing over 23,000 children conceived through IVF, and compared to those conceived naturally. The findings on overall cognitive function were mixed, as measured by IQ.

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Heart failure is a complex and prevalent condition with significant implications for patient management and survival prediction. Traditional predictive models often fall short in accuracy due to their reliance on pre-specified predictors and assumptions of variable independence. This review aims to assess the role of machine learning (ML) algorithms in predicting heart failure survival, comparing their performance with traditional statistical methods and identifying key predictive features.

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Background: Substance use and abuse of psychoactive substances, alcohol, and illicit drugs, result in dependence, crimes, illicit financial flows, corruption, and terrorism/insurgency.

Objectives: To evaluate the risk factors, prevalence, and patterns of substance abuse, among adult patients attending the Behavioural Medical Unit, Karu General Hospital, Abuja; for prevention and early clinical diagnosis.

Method: A hospital-based descriptive cross-sectional study conducted, from March 2022 to May 2022; involving 257 consenting adults, 18 years and above, selected through systematic random sampling.

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African immunization programs are crucial in reducing the prevalence of infectious diseases and improving public health outcomes. This review provides an overview of the current status of immunization efforts in Africa, highlights key challenges, and offers recommendations to help the continent achieve the 2030 Global Immunization Goals. While progress has been made, significant challenges remain.

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Article Synopsis
  • * Low- and middle-income countries in Africa suffer significant health consequences from WASH-related diseases, with issues like poverty, illiteracy, and climate change hindering effective interventions and leading to millions of deaths annually.
  • * Recommendations for improving WASH practices include implementing strong financial frameworks, providing skills training, and utilizing tools like WASH Fit to enhance infrastructure and address health impacts while also contributing to economic growth and sustainability.
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  • * A systematic review and meta-analysis of existing literature found a migraine prevalence of 16% among 7,768 participants in Nigeria, with higher rates in women and various common triggers identified, such as fatigue and emotional stress.
  • * The conclusion stresses the urgent need for improved healthcare policies and treatment strategies, as many individuals experience inadequate pain relief and side effects from common migraine medications.
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  • Polycystic ovary syndrome (PCOS) is a common hormonal disorder in women of reproductive age, influenced by genetics, hormones, and environmental factors.* -
  • Serum kisspeptin is highlighted as a potential biomarker for PCOS due to its role in regulating the hypothalamic-pituitary-gonadal (HPG) axis, but there are challenges in utilizing it effectively for diagnosis.* -
  • The review stresses the need for standardized research methods and further investigation into genetic variations to improve the reliability of kisspeptin as a diagnostic tool for PCOS.*
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  • * A review of studies from 2000 to February 2024 reveals that these conditions lead to significant memory and cognitive impairments in mothers and cognitive deficits in their children due to factors like placental issues and maternal stress.
  • * The research calls for a better understanding of the causes and the development of early interventions to help improve cognitive health in affected mothers and children through a multidisciplinary approach.
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The burden of meningitis poses great challenges for neurology and global health, manifesting with a range of symptoms from mild fever and headaches, to severe long term complications such as paralysis and cognitive impairment.. Unfortunately, those living in endemic regions, especially survivors, are often confronted with the harsh reality of reduced quality of life as measured by disability-adjusted life years.

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Background: Breastfeeding is crucial in providing infants with needed nutrition and immunity to foster their healthy growth and development; yet, optimal support from health workers is critical for it to be successful.

Aim: To determine factors influencing tangible breastfeeding support among health workers in Nigeria.

Methods: This cross-sectional study was conducted in Nigeria's six geopolitical zones between August 2022 and February 2023 among health workers ( = 2,922).

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Stem cell therapy (SCT) is a promising solution for addressing health challenges in Africa, particularly non-communicable diseases (NCDs). With their regenerative potential, stem cells have the inherent capacity to differentiate into numerous cell types for tissue repair. Despite infrastructural, ethical, and legal challenges, SCT holds immense promise for managing chronic illnesses and deep-seated tissue injuries.

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  • Gestational Diabetes Mellitus (GDM) poses health risks, making early prediction and effective management essential, with machine learning proving to be a useful tool in this area.*
  • A review of fourteen studies published from 2000 to September 2023 focused on machine learning techniques for predicting GDM, highlighting key themes such as the need for early risk prediction and tailored models for different populations.*
  • The findings suggest integrating clinical data into GDM prediction models enhances treatment delivery, but complexities in model selection and variable weighting remain challenges for researchers seeking to improve healthcare outcomes for at-risk pregnant individuals.*
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  • * Key obstacles include poor environmental sanitation, contaminated water and food, and the impact of climate change, which exacerbate cholera spread and hinder progress towards the 2030 targets of a 90% reduction in cases and deaths.
  • * Despite these hurdles, achieving global cholera eradication is possible with strengthened institutional support and the implementation of evidence-based public health strategies, guided by the Global Roadmap to Ending Cholera Outbreaks by 2030.
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  • Ovarian cancer is a leading cause of death among gynecologic cancers, and this paper investigates the use of mirvetuximab soravtansine, a targeted therapy for platinum-resistant ovarian cancer expressing folate receptor alpha (FRα).
  • Four key studies involving 453 participants show that mirvetuximab soravtansine is effective in fighting tumors with a good safety profile, particularly beneficial for tumors with high FRα expression.
  • While the treatment shows promise for enhancing therapy outcomes, further research is needed to address patient diversity, improve quality of life data, and understand long-term safety, as well as to identify more biomarkers for personalized treatment options.
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Background: Like many low- and-middle-income countries in Africa, documented assessment of the neurosurgical workforce, equipment, infrastructure, and scope of service delivery in Nigeria is lacking. This study aimed to assess the capacity for the delivery of neurosurgical services in Nigeria.

Methods: An 83-question survey was disseminated to neurosurgeons and residents in Nigeria.

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Objective: There has been a modest but progressive increase in the neurosurgical workforce, training, and service delivery in Nigeria in the last 2 decades. However, these resources are unevenly distributed. This study aimed to quantitatively assess the availability and distribution of neurosurgical resources in Nigeria while projecting the needed workforce capacity up to 2050.

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Introduction Benign lipomatous tumors are soft tissue tumors that exhibit a predominant adipocytic phenotype. Lipomas are the archetype and are the most common benign soft tissue tumors in adults but relatively uncommon in children. Their sex incidence is equivocal.

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The healthcare industry is constantly evolving to bridge the inequality gap and provide precision care to its diverse population. One of these approaches is the integration of digital health tools into healthcare delivery. Significant milestones such as reduced maternal mortality, rising and rapidly proliferating health tech start-ups, and the use of drones and smart devices for remote health service delivery, among others, have been reported.

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  • - Group B streptococcus (GBS) poses serious risks to newborns, prompting research into maternal vaccination as a preventative measure due to limitations of current intrapartum antibiotics.
  • - A review of five studies indicated that maternal GBS vaccines are effective and generally safe, though varying immune responses highlight the need for personalized vaccination strategies.
  • - Successful integration of GBS vaccination into maternal health programs faces challenges, particularly in resource-limited settings, necessitating efforts to address cultural barriers and improve healthcare provider knowledge.
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Ovarian cancer presents a significant health challenge in sub-Saharan Africa (SSA), where late-stage diagnosis contributes to high mortality rates. This diagnostic gap arises from limited resources, poor healthcare infrastructure, and a lack of awareness about the disease. However, a potential game-changer is emerging in the form of liquid biopsy (LB), a minimally invasive diagnostic method.

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