[Biliary endoprosthesis using Gore-Tex covered expandable metallic stents: preliminary clinical evaluation].

Six patients with biliary obstruction caused by pancreatic carcinoma were treated with Gore-Tex covered EMS. In all cases cholangioscopy revealed massive tumor in the bile duct lumen, but all stents expanded well and equalled the caliber of the bile duct. Slipping migration was observed in 2 patients, in whom external drainage catheters could not be removed.

[Concomitant arterial infusion chemotherapy with tamoxifen therapy for hepatic metastases from pancreatic adenocarcinoma--a preliminary report].

The prognosis for hepatic metastasis from pancreatic adenocarcinoma is generally poor. Estrogen receptors have recently been demonstrated in pancreatic adenocarcinoma, and it has been suggested that tamoxifen increases patient survival. We have tried tamoxifen therapy combined with intermittent intraarterial infusion chemotherapy using mainly 5-FU for 4 patients with hepatic metastasis from pancreatic adenocarcinoma.

[Benefits of totally implanted central venous access in patients with cancer].

A totally implanted system for improved central venous access has been investigated during 44 procedures in 38 patients (37 with cancer and one with cerebral infarction). Most of them lacked peripheral venous sites, and ten per cent of the patients had a prior chronic external central venous catheter. This system is implanted using local anesthesia and consists of a port connected to a central venous catheter threaded through the subclavian vein into the superior vena cava.