DDX60 Promotes Migration and Invasion of Head and Neck Squamous Cell Carcinoma Cell through the NF-κB/IFI27 Signaling Pathway.

Background: Despite its significance in multiple cancer types. the function and mechanism of DEXD/H box helicase 60 (DDX60) in head and neck squamous cell carcinoma (HNSCC) remain unreported.

Methods: Thirty paired HNSCC tissues and adjoining normal tissues and human normal oral epithelial keratinocytes (HOK) and four HNSCC cells (CAL27, SAS, CAL33, and SCC25) were analyzed for DDX60 expression by Semi-quantitative real-time PCR (SQ RT-PCR) and western blot.

Propofol inhibits proliferation and migration of glioma cells by up-regulating lncRNA GAS5.

Propofol has been documented to exhibit anti-tumor effects in cancers. However, the underlying mechanisms of its inhibition remain unclear. We conducted this study to investigate the effect of propofol on lncRNA GAS5 in glioma cells, and to probe the role of GAS5 in the anti-tumor effects of propofol.

Association of MUC2, MUC5AC and MUC5B genes with the recurrence of nasal polyps.

Although mucins were suggested to contribute to the pathogenesis of nasal polyposis, the correlation between the expression levels of MUC5AC, MUC5B and MUC2, and the recurrence of nasal polyps, has not been extensively investigated. The present study aimed to investigate the association of the levels of mucin (MUC) 2, MUC5AC and MUC5B with the recurrence of nasal polyps. A total of 56 patients with nasal polyps who underwent functional endoscopic sinus surgery at the Tianjin Third Central Hospital (Tianjin, China) between June 2007 and June 2010 were included and baseline characteristics were recorded.