409 results match your criteria: "Army Dental Centre Research & Referral.[Affiliation]"

As a result of armed conflict, head trauma from exposure to blasts is an increasing critical health issue, particularly among military service members. Whilst numerous studies examined the burden of blast-related brain injuries on service members', few systematic reviews have been published. This work provides a comprehensive summary of the evidence on blast-related mild traumatic brain injury (mTBI) burden in active U.

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Chitosan capping of CuO nanoparticles: Facile chemical preparation, biological analysis, and applications in dentistry.

Int J Biol Macromol

January 2021

Department of Tissue Engineering, China Medical University, Shenyang 110122, China; Institute of Regulatory Science for Medical Device, National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610064, China.

This investigation is vital contribution to the healthcare system utilizing techniques of nanobiotechnology. It interestingly applies chitosan capped CuO nanoparticles in the field of medicine and restorative dentistry. The CuO nanoparticles and CuO-Chitosan nanoparticles are prepared by co-precipitation, and their characterization is performed using X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), transmission electron microscopy (TEM), and energy dispersive X-ray (EDX).

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Effects of Er:YAG laser pre-treatment on dentin structure and bonding strength of primary teeth: an in vitro study.

BMC Oral Health

November 2020

State Key Laboratory of Military Stomatology and National Clinical Research Center for Oral Disease and Shaanxi Clinical Research Center for Oral Diseases, Stomatology Department of Children, School of Stomatology, The Fourth Military Medical University, No. 145, Changle West Road, Xincheng District, Xi'an, Shaanxi, China.

Background: To investigate the effects of Er:YAG laser pre-treatment on the dentin structure and shear bond strength of primary teeth.

Methods: Dentin specimens were prepared using freshly extracted intact primary molars and divided randomly into four groups based on the surface treatment applied. The control and etchant groups received no treatment and conventional acid etching treatment, respectively, while the energy and frequency groups received laser surface treatment with variable energy (50-300 mJ) and frequency (5-30 Hz) parameters.

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Article Synopsis
  • - The study aimed to assess the effectiveness of using a sublingual gland flap for reconstructing surgical defects after sequestrectomy in patients with MRONJ, osteomyelitis, and osteoradionecrosis of the mandible.
  • - Six patients (3 males and 3 females, ages 45-71) underwent the procedure under local anesthesia and were monitored for outcomes including complete healing, pain, and the risk of infection over 1 to 6 months.
  • - Results showed that all patients achieved complete healing without complications such as pain, inflammation, or postoperative infections, indicating that this reconstruction method is effective for small to medium-sized oral defects.
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Drug Repurposing in Neurological Disorders: Implications for Neurotherapy in Traumatic Brain Injury.

Neuroscientist

December 2021

Program for Neurotrauma, Neuroproteomics & Biomarkers Research, Departments of Emergency Medicine, Psychiatry, Neuroscience and Chemistry, University of Florida, Gainesville, FL, USA.

Article Synopsis
  • Traumatic brain injury (TBI) is a major global cause of death and disability, yet no FDA-approved drugs effectively treat it.
  • Due to the challenges in developing new drugs, there's a growing interest in repurposing existing, safer medications as a more efficient alternative for TBI treatment.
  • The review discusses several FDA-approved drugs, like edaravone and progesterone, that show potential in providing neuroprotection for TBI, supported by recent studies on their effectiveness.
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Genomic Adaptations and Evolutionary History of the Extinct Scimitar-Toothed Cat, Homotherium latidens.

Curr Biol

December 2020

Section for Evolutionary Genomics, The GLOBE Institute, University of Copenhagen, Øster Voldgade 5-7, Copenhagen, Denmark; Department of Natural History, NTNU University Museum, Norwegian University of Science and Technology (NTNU), Trondheim NO-7491, Norway; Center for Evolutionary Hologenomics, The GLOBE Institute, University of Copenhagen, Øster Farimagsgade 5A, Copenhagen 1352, Denmark. Electronic address:

Article Synopsis
  • Homotherium was a large, extinct genus of scimitar-toothed cats with unique physical traits suited for hunting large Pleistocene mammals.
  • Genetic analyses indicate that Homotherium diverged from modern cats about 22.5 million years ago, showing no signs of interbreeding with current felids.
  • The study revealed high genetic diversity in Homotherium, suggesting it was potentially more abundant than indicated by the fossil record, and highlights its adaptations in vision, behavior, and hunting strategies.
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Pharyngoesophageal Segment Distention Across Volumes and Pathology.

J Speech Lang Hear Res

November 2020

Department of Otolaryngology-Head and Neck Surgery, Brooke Army Medical Center, Joint Base San Antonio-Fort Sam Houston, TX.

Purpose Patients receive multiple bolus trials during a videofluoroscopic swallowing study (VFSS) to assess swallow function, inclusive of narrowing within the pharyngoesophageal segment (PES). While differences in the narrowest and widest segments are visualized, the ratio of distention across boluses is not well understood. Method A retrospective review of 50 consecutive VFSSs with five boluses of varied viscosity and volume was performed.

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A four-year prospective study of self-assembling nano-modified dental implants in patients with type 2 diabetes mellitus.

J Dent Sci

September 2020

State Key Laboratory of Military Stomatology and National Clinical Research Center for Oral Diseases and Shaanxi Clinical Research Center for Oral Diseases, Department of Orthodontics, School of Stomatology, Fourth Military Medical University, Xi'an, PR China.

Background/purpose: Dental implantation has become an efficient and important method of replacing lost teeth. However, the success rate of dental-implant treatment in diabetics is higher than patients without diabetes. The aim of this study was to prospectively evaluate long-term marginal bone loss (MBL) and the stability of a self-assembling nano-modified implant in patients with type 2 diabetes mellitus compared with a conventional implant.

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Correlation of Glottic Gap and Voice Impairment in Presbyphonia.

Laryngoscope

July 2021

Department of Otolaryngology-Head and Neck Surgery, Birmingham, Alabama, U.S.A.

Objective/hypothesis: The objective of this study was to investigate the glottic gap area as a significant marker for the severity of presbyphonia as it relates to patient-reported outcome measures (Voice Handicap Index-10 [VHI-10]) and stroboscopic findings.

Study Design: Retrospective case-control study conducted in an academic tertiary voice center.

Methods: Patients seen at a tertiary voice clinic who were diagnosed with presbyphonia without other organic laryngeal pathology from January 2014 to December 2017 were included.

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Insertion tendinosis of stylomandibular ligament (SML) or Ernest syndrome is a very rare and under reported head and neck pain disorder. The pain originates from the insertion of stylomandibular region and radiates to the temple, lateral side of the neck and temporomandibular joint (TMJ). The diagnosis is confirmed by palpation of SML and local anesthetic block at the insertion of SML.

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Chitosan encapsulated ZnO nanocomposites: Fabrication, characterization, and functionalization of bio-dental approaches.

Mater Sci Eng C Mater Biol Appl

November 2020

Department of Tissue Engineering, China Medical University, Shenyang 110122, China; Institute of Regulatory Science for Medical Device, National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610064, China. Electronic address:

Current report is paramount contribution via nanotechnology to the existing remedies of health diseases. The lag in application of capped metallic oxide nanoparticles in restorative dentistry exist which is covered by this promising study. The uncapped and chitosan encapsulated ZnO nanoparticles were fabricated by facile co-precipitation method, and characterized using various biophysical strategies including X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM) and Energy dispersive x-ray (EDX).

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Objective: We sought to determine the time course of clinical and histologic differences between aspirated inorganic and organic foreign bodies.

Study Design: In-vivo.

Methods: Twenty Sinclair miniature swine (Sus scrofa domesticus) were divided into two groups-inorganic or organic foreign bodies.

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Objective:  The infrared rays is one of the treatments to relief of dental pain due to pulpitis or periodontitis. The ability of infrared to increase the pain threshold which make eliminating P substance on the inflammation area and inducing Aβ and Aδ fibers to activate γ-aminobutyrate (GABA) and neuropeptides to decrease the pain. Hence, reducing or eliminating dental pain.

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Evidence of differences in operator-related outcomes between single and double puncture arthrocentesis is limited. The purpose of this prospective study was to compare intraoperative outcomes with single puncture types 1 and 2, and double puncture, arthrocentesis. A total of 59 patients with 60 temporomandibular joints (TMJ) were treated sequentially by single puncture type 1 (n=20), single puncture type 2 (n=20), and double puncture arthrocentesis (n=20).

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Objective: To identify the prevalence of and factors associated with the use of dental health services to receive professionally applied topical fluoride (DHSU-PATF) in the 12 months prior to the study among Mexican schoolchildren aged 6 to 12 years.

Methods: A cross-sectional study was performed in 1,404 schoolchildren selected randomly from 15 public schools in the city of Pachuca, Mexico. Questionnaires were distributed to determine the demographic, socioeconomic, and behavioral variables.

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BACKGROUND Zirconia is one of the most widely used ceramic materials for transplanting and treating caries. This study aimed to synthesize zirconium oxide (ZrO₂) nanotubes and evaluated their characteristics. MATERIAL AND METHODS Zr film was prepared using an ion plating method.

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Full-mouth Rehabilitation of a Ventriculoperitoneal Shunt-treated Hydrocephalic Pediatric Patient: A Case Report.

Int J Clin Pediatr Dent

January 2020

Department of Pedodontics and Preventive Dentistry, Army Dental Centre, Research and Referral, New Delhi, India.

Hydrocephalus is characterized by accumulation of cerebrospinal fluid in the lateral ventricles of the brain, which results in progressive ventricular dilatation and an increased intracranial pressure. A ventriculoperitoneal shunt (VPS) is the most common treatment for hydrocephalus. Delayed development, behavioral disturbance, chronological changes in the eruption of their teeth, changes in the occlusion, greater accumulation of plaque, and increased caries prevalence are some of the clinical manifestations in these patients, which are encountered by a pediatric dentist.

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Purpose: This study aimed to determine whether complete dentures improve the oral health-related quality of life (OHRQoL) of edentulous patients, and to assess any associations related to age, gender, and OHRQoL.

Material And Methods: Hundred edentulous patients who required conventional complete denture treatment were selected for this study. The following inclusion criteria were established: edentulous in both jaws with no previous history of denture treatment and no significant medical history.

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Objective: Antimicrobial peptide, KSL-W, formulated as an antiplaque chewing gum (APCG), was tested to evaluate the dental plaque inhibition activity and safety in an IRB approved and FDA regulated 4-day plaque regrowth clinical study.

Methods: This Phase 2 two-armed placebo-controlled, double blind, randomized (1:1), multiple dose, and single-center study was evaluated in a proof of concept for the APCG containing 30 mg antimicrobial peptide KSL-W. Twenty six generally healthy subjects were consented and randomized into the study.

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Article Synopsis
  • The study aimed to assess the frequency of abnormal findings in fiberoptic endoscopic evaluation of swallowing (FEES) among patients with progressive neurological disorders and to identify common dysphagia management strategies used.* -
  • It involved a retrospective review of 209 assessments conducted between 2008 and 2019, revealing that many patients exhibited issues like penetration (72.5%) and aspiration (14.6%), with related Eating Assessment Tool-10 (EAT-10) scores indicating severity.* -
  • The majority (88%) of patients required a functional change in management, mostly involving self-directed dietary modifications, while some (19%) were recommended to use a PEG tube for nutrition, highlighting the need for early evaluation of swallowing
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To evaluate clinical effect of deproteinized bovine bone for delayed implantation after fenestration. This trial is a continuation of a prospective clinical trial. From May 2011 to February 2015 in Department of Implantology, School of Stomatology, The Fourth Military Medical University after planting division of 55 cases of maxillary teeth missing area of residual alveolar bone height ≤5 mm patients.

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Mesenchymal stem cells from orthodontic premolar teeth.

Med J Armed Forces India

April 2020

Senior Consultant, Haemato-Oncology & Bone Marrow Transplant, Comprehensive Blood & Cancer Center (CBCC), 632, C-1, Ansals Palam Vihar, Carterpuri, Gurgaon 122017, India.

Background: Considering the limitations in isolating Bone Marrow Mesenchymal Stem Cells (BMSCs), alternate sources of Mesenchymal Stem Cells (MSCs) are being intensely investigated. This study evaluated dental pulp MSCs (DP-MSCs) isolated from orthodontically extracted premolar teeth from a bone tissue engineering perspective.

Methods: MSCs isolated from premolar teeth pulp were cultured and studied using BMSCs as the control.

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Traumatic brain injury (TBI) is a major cause of disability worldwide, but the heterogeneous nature of TBI with respect to injury severity and health comorbidities make patient outcome difficult to predict. Injury severity accounts for only some of this variance, and a wide range of preinjury, injury-related, and postinjury factors may influence outcome, such as sex, socioeconomic status, injury mechanism, and social support. Neuroimaging research in this area has generally been limited by insufficient sample sizes.

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A comprehensive review of the neurological disorders reported during the current COVID-19 pandemic demonstrates that infection with SARS-CoV-2 affects the central nervous system (CNS), the peripheral nervous system (PNS) and the muscle. CNS manifestations include: headache and decreased responsiveness considered initial indicators of potential neurological involvement; anosmia, hyposmia, hypogeusia, and dysgeusia are frequent early symptoms of coronavirus infection. Respiratory failure, the lethal manifestation of COVID-19, responsible for 264,679 deaths worldwide, is probably neurogenic in origin and may result from the viral invasion of cranial nerve I, progressing into rhinencephalon and brainstem respiratory centers.

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The evolutionary history of extinct and living lions.

Proc Natl Acad Sci U S A

May 2020

Section for Evolutionary Genomics, The GLOBE Institute, Faculty of Health and Medical Sciences, University of Copenhagen, 1353 Copenhagen, Denmark;

Lions are one of the world's most iconic megafauna, yet little is known about their temporal and spatial demographic history and population differentiation. We analyzed a genomic dataset of 20 specimens: two 30,000-y-old cave lions (), 12 historic lions () that lived between the 15th and 20th centuries outside the current geographic distribution of lions, and 6 present-day lions from Africa and India. We found that cave and modern lions shared an ancestor 500,000 y ago and that the 2 lineages likely did not hybridize following their divergence.

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