Relationships between Workload, Heart Rate Variability, and Performance in a Recreational Endurance Runner.

Background: The association between heart rate variability (HRV), training load (TL), and performance is poorly understood.

Methods: A middle-aged recreational female runner was monitored during a competitive 20-wk macrocycle divided into first (M1) and second mesocycle (M2) in which best performances over 10 km and 21 km were recorded. Volume (km), session rating of perceived exertion (sRPE), TL, and monotony (mean TL/SD TL) were the workload parameters recorded.

Medication adherence and barriers among low-income, uninsured patients with multiple chronic conditions.

Background: Poor adherence to long-term therapies is a public health concern that affects all populations. Little is known about the context of adherence in chronic diseases for the uninsured population in the United States.

Objective: To evaluate medication adherence and barriers among low-income, uninsured adults recently initiating new therapy for a chronic disease.

The Demands of a Women's College Soccer Season.

The purpose of this study was to use GPS, accelerometers, and session rating of perceived exertion (sRPE) to examine the demands of a Division II women's soccer team. Data was collected on 25 collegiate Division II women's soccer players over an entire regular season (17 matches and 24 practices). Zephyr BioHarnesses (BHs) were used to collect tri-axial acceleration information and GPS derived variables for all matches and practices.

Epigenetic and genetic variation among three separate introductions of the house sparrow () into Australia.

Invasive populations are often associated with low levels of genetic diversity owing to population bottlenecks at the initial stages of invasion. Despite this, the ability of invasive species to adapt rapidly in response to novel environments is well documented. Epigenetic mechanisms have recently been proposed to facilitate the success of invasive species by compensating for reduced levels of genetic variation.

Visualization of mercury(ii) accumulation in vivo using bioluminescence imaging with a highly selective probe.

Mercury is a highly toxic environmental pollutant that negatively affects human health. Thus, an in vivo method for noninvasive imaging of mercury(ii) and visualization of its accumulation within living systems would be advantageous. Herein, we describe a reaction-based bioluminescent probe for detection of mercury(ii) in vitro and accumulation in vivo.

A Biomechanical Analysis of the Effects of Bouncing the Barbell in the Conventional Deadlift.

Krajewski, K, LeFavi, R, and Riemann, B. A biomechanical analysis of the effects of bouncing the barbell in the conventional deadlift. J Strength Cond Res 33(7S): S70-S77, 2019-The purpose of this study is to analyze biomechanical differences between the bounce and pause styles of deadlifting.

Differences in the motor unit firing rates and amplitudes in relation to recruitment thresholds during submaximal contractions of the first dorsal interosseous between chronically resistance-trained and physically active men.

Previous investigations report no changes in motor unit (MU) firing rates during submaximal contractions following resistance training. These investigations did not account for MU recruitment or examine firing rates as a function of recruitment threshold (REC). Therefore, MU recruitment and firing rates in chronically resistance-trained (RT) and physically active controls (CON) were examined.

Alcohol and drug screening and brief intervention behaviors among advanced practice registered nurse (APRN) students in clinical settings.

Previous research on training health professionals to identify and address unhealthy alcohol and drug use in patients through screening, brief intervention, and referral to treatment (SBIRT) has found that training increases knowledge about substance use and increases students' confidence in addressing substance use in patients. To date, however, there is little information on how health professional students integrate SBIRT into individual practice. Within a U.

Candida albicans-derived mannoproteins activate NF-κB in reporter cells expressing TLR4, MD2 and CD14.

The ability of soluble C. albicans 20A (serotype A) mannoprotein (CMP) to serve as a ligand for toll-like receptor 4 (TLR4) and its co-receptors was examined using commercially available and stably-transfected HEK293 cells that express human TLR4, MD2 and CD14, but not MR. These TLR4 reporter cells also express an NF-κB-dependent, secreted embryonic alkaline phosphatase (SEAP) reporter gene.

The Level of Cognitive Impairment and Likelihood of Frequent Hospital Admissions.

This study aims to examine the relationship between different levels of cognitive impairment (CI) and the frequency of hospital admission (HA). Data from the National Health and Aging Trend Study, Round 1 (2011), with 8,245 respondents from Medicare beneficiaries were used. The data account for the number of hospital admissions for one year before the data collection.

Manganese(II) chloride complexes with pyridine -oxide (PNO) derivatives and their solid-state structures.

Three manganese(II) -oxide complexes have been synthesized from the reaction of manganese(II) chloride with either pyridine -oxide (PNO), 2-methyl-pyridine -oxide (2MePNO) or 3-methyl-pyridine -oxide (3MePNO). The compounds were synthesized from methano-lic solutions of MnCl·4HO and the respective -oxide, and subsequently characterized structurally by single-crystal X-ray diffraction. The compounds are -poly[[aqua-chlorido-manganese(II)]-di-μ-chlorido-[aqua-chlorido-manganese(II)]-bis-(μ-pyridine -oxide)], [MnCl(CHNO)(HO)] or [MnCl(PNO)(HO)] (), -poly[[aqua-chlorido-man-gan-ese(II)]-di-μ-chlorido-[aqua-chlorido-manganese(II)]-bis-(μ-2-methyl-pyridine -oxide)], [MnCl(CHNO)(HO)] or [MnCl(2MePNO)(HO)] (), and bis-(μ-3-methyl-pyridine -oxide)bis-[di-aqua-dichlorido-manganese(II)], [MnCl(CHNO)(HO)] or [MnCl(3MePNO)(HO)] ().

Osteoporosis in Patients with CKD: A Diagnostic Dilemma.

Osteoporosis in patients with chronic kidney disease (CKD) is a complex problem, with diagnostic criteria and treatment plans often debated. The debate creates a practice dilemma for clinicians faced with an aging population and an increasing incidence of fragility fractures. This article discusses the dilemma as seen from the perspective of the nephrology clinician on differentiating osteoporosis from other bone mineral disorders in patients with progressive CKD in order to provide the most efficacious and safe care.

Age related changes in balance performance during self-selected and narrow stance testing.

Background: Various balance tests have been considered as fall risk screening tools however there is a lot of variability in the methods and outcome measures reported. Based on previous research examining age-related changes in balance and differences between fallers and nonfallers, the purpose of this investigation was to examine age-related balance changes, as reflected in medial-lateral center of pressure (CP) velocity, in community-dwelling/independently living adults (≥60years) during self-selected and narrow stance testing with eyes opened and closed.

Methods: Two hundred and thirty adults aged 60yrs or older completed one 45s trial under two stances (self-selected, narrow) and two visual conditions (eyes opened, eyes closed).

Genetic and epigenetic variation in following the oil spill.

Catastrophic events offer unique opportunities to study rapid population response to stress in natural settings. In concert with genetic variation, epigenetic mechanisms may allow populations to persist through severe environmental challenges. In 2010, the oil spill devastated large portions of the coastline along the Gulf of Mexico.

Ultra-shortened time-domain HRV parameters at rest and following exercise in athletes: an alternative to frequency computation of sympathovagal balance.

Purpose: The primary purpose of this study was to determine the accuracy of the standard deviation of normal-to-normal intervals (SDNN) to root mean square of successive normal-to-normal interval differences (RMSSD) ratio from 1-min recordings (SDNN:RMSSD) compared to criterion recordings, as well as its relationship to low-frequency-to-high-frequency ratio (LF:HF) at rest and following maximal exercise in a group of collegiate athletes.

Method: Twenty athletes participated in the study. Heart rate variability (HRV) data were measured for 5 min before and at 5-10 and 25-30 min following a maximal exercise test.

Heart Rate Variability and Training Load Among National Collegiate Athletic Association Division 1 College Football Players Throughout Spring Camp.

Flatt, AA, Esco, MR, Allen, JR, Robinson, JB, Earley, RL, Fedewa, MV, Bragg, A, Keith, CM, and Wingo, JE. Heart rate variability and training load among National Collegiate Athletic Association Division 1 college football players throughout spring camp. J Strength Cond Res 32(11): 3127-3134, 2018-The purpose of this study was to determine whether recovery of cardiac-autonomic activity to baseline occurs between consecutive-day training sessions among positional groups of a collegiate football team during Spring camp.

Kinetic and kinematic patterns during high intensity clean movement: searching for optimal load.

The aim of the present study was to investigate loading effects on kinematic and kinetic variables among elite-weightlifters in order to identify an optimal training load to maximize power production for clean-movement. Nine elite-weightlifter (age: 24 ± 4years, body-mass: 77 ± 6.5kg, height: 176 ± 6.

Design and synthesis of benzopyran-based inhibitors of the hypoxia-inducible factor-1 pathway with improved water solubility.

While progress has been made in treating cancer, cytotoxic chemotherapeutic agents are still the most widely used drugs and are associated with severe side-effects. Drugs that target unique molecular signalling pathways are needed for treating cancer with low or no intrinsic toxicity to normal cells. Our goal is to target hypoxic tumours and specifically the hypoxia inducible factor (HIF) pathway for the development of new cancer therapies.

Within-session reversal learning in rhesus macaques (Macaca mulatta).

In a midsession reversal (MSR) task, animals are typically presented with a simple, simultaneous discrimination (S1+, S2-) where contingencies are reversed (S1-, S2+) half-way through each session. This paradigm creates multiple, relevant cues that can aid in maximizing overall reinforcement. Recent research has shown that pigeons show systematic anticipatory and perseverative errors across the session, which increase as a function of proximity to the reversal trial.

Effects of Trial Duration on Intrasession Reliability of Single Leg Balance Testing on Stable and Unstable Surfaces.

Context: Single leg balance testing is a commonly used tool in sports medicine; however, there has been no consensus on trial duration needed to obtain reliable measures.

Objective: This investigation sought to determine the minimum trial duration required to obtain the highest intrasession single and average trial reliability for single leg balance testing on stable and unstable surfaces using dominant and nondominant limbs.

Design: Intrasession reliability.

ACL Return to Sport Guidelines and Criteria.

Purpose Of Review: Because of the epidemiological incidence of anterior cruciate ligament (ACL) injuries, the high reinjury rates that occur when returning back to sports, the actual number of patients that return to the same premorbid level of competition, the high incidence of osteoarthritis at 5-10-year follow-ups, and the effects on the long-term health of the knee and the quality of life for the patient, individualizing the return to sports after ACL reconstruction (ACL-R) is critical. However, one of the challenging but unsolved dilemmas is what criteria and clinical decision making should be used to return an athlete back to sports following an ACL-R. This article describes an example of a functional testing algorithm (FTA) as one method for clinical decision making based on quantitative and qualitative testing and assessment utilized to make informed decisions to return an athlete to their sports safely and without compromised performance.

Discrepancies in publications related to HMB-FA and ATP supplementation.

This letter addresses a number of discrepancies found in several publications related HMB-FA and ATP supplementation.