3,472 results match your criteria: "Armed Forces Hospital.[Affiliation]"

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  • * A total of 18 studies with 2,457 participants were examined, revealing that cognitive dysfunction affects 11.5% to 70% of adults and 10.2% to 68.2% of children with SCA, influenced by factors such as educational and economic status, age, and prior strokes.
  • * The study emphasizes that cognitive decline is a critical concern for individuals with SCA across all ages and suggests the need for targeted medical interventions and further research on various influencing factors.
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  • A study conducted in Jordan aimed to decrease vaccine hesitancy among parents regarding the measles and rubella (MR) vaccine by using an educational video intervention.
  • The video showed a significant improvement in parents' attitudes towards the vaccine, with their acceptance likely increasing immediately after watching and remaining positive two weeks later.
  • Results indicated that the educational approach effectively reduced the likelihood of vaccine refusal, suggesting similar interventions could be beneficial in other regions facing vaccine hesitancy.
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  • A hybrid strategy combining plug-based and suture-based vascular closure devices (VCDs) was studied to determine the effectiveness of ProGlide/AngioSeal versus ProGlide/FemoSeal after transcatheter aortic valve implantation (TAVI).
  • A retrospective study of 608 patients revealed that the ProGlide/AngioSeal group had significantly higher rates of major bleeding and overall complications compared to the ProGlide/FemoSeal group.
  • The findings suggest that using ProGlide/FemoSeal may lead to better outcomes within 30 days and that anterior wall calcification at the access site increases the risk of complications.
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Green and High Throughput Assay Using 96-Microwell Base to Determine Metformin Hydrochloride in the Tablet Dosage Form.

Int J Anal Chem

August 2024

Department of Pharmaceutical Chemistry, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.

Article Synopsis
  • Metformin (MET) is a primary treatment for type 2 diabetes, and the study focuses on improving quality control methods for its analysis in pharmaceutical formulations.
  • The researchers developed and validated a 96-microwell plate spectrophotometer method using charge-transfer complexes with chloranilic acid and DDQ, demonstrating high precision and accuracy for quantifying MET.
  • The new method is efficient, cost-effective, and environmentally friendly, making it a superior alternative for routine MET analysis in quality control laboratories compared to traditional methods.
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  • Over the past 20 years, the European School of Urology (ESU) has implemented various educational programs, including e-learning, courses, webinars, and the European Urology Resident Education Program (EUREP), to standardize training in urology.
  • From 2004 to 2022, participation in ESU courses grew significantly, with 4,750 attendees and EUREP attracting 5,958 trainees, showing a notable increase in female participation from 10.7% to 37.1%.
  • The average age of participants has decreased over time, indicating a growing influx of younger urologists, which reflects the ESU's commitment to modernizing urological education and improving patient care.
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Statins differ in their solubility. Some previous studies suggested a difference in clinical efficacy and adverse events between hydrophilic and lipophilic statins. The purpose of this study is to compare the efficacy and safety of hydrophilic and lipophilic statins in patients with acute coronary syndrome.

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  • The study investigates the use of nebulized tranexamic acid (TXA) for treating post-tonsillectomy bleeding (PTB), a common complication leading to emergency department visits.
  • By systematically reviewing nine studies, the researchers assessed the effectiveness and safety of nebulized TXA, finding a lower reoperation rate for those treated with TXA compared to those who weren't.
  • The results suggest that nebulized TXA is a safe and effective treatment for PTB, but more extensive research is needed to confirm these findings.
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Introduction Asthma is a common chronic airway disorder, particularly among children in Saudi Arabia, with an increasing global prevalence. Limited epidemiological studies in the region indicate variable asthma rates, potentially influenced by factors such as modernization and environmental changes. Given the potential health benefits of breastfeeding, it is critical to investigate the relationship between type of feeding, and asthma risk.

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  • This study investigated how often children with autism spectrum disorder (ASD) experience gastrointestinal (GI) symptoms and what factors might be related to those symptoms.
  • It included a total of 146 children with ASD and 114 typically developing children, using a questionnaire to gather data on demographics, nutrition, and GI health over the past six months.
  • Results showed that children with ASD reported more GI issues like constipation and diarrhea, and factors such as family history of ASD and maternal education levels were linked to these symptoms.
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Background: Autism spectrum disorder (ASD) is a complex neurodevelopmental condition that is significantly increasing, resulting in severe distress. The approved treatment for ASD only partially improves the sympoms, but it does not entirely reverse the symptoms. Developing novel disease-modifying drugs is essential for the continuous improvement of ASD.

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  • Displaced femoral neck fractures are common in older adults and often require surgery, with hemiarthroplasty being a typical treatment option.
  • A case study reports the successful use of cementless hemiarthroplasty in a 93-year-old woman, demonstrating its benefits like shorter surgery time and less blood loss.
  • The positive outcome with no early complications highlights the need for individualized patient care and suggests further research to better define cementless techniques' roles in elderly patients.
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Mandibulectomy with free fibular flap reconstruction is a well-established procedure in head and neck surgery, recognized for its functional and aesthetic outcomes. However, this procedure carries certain risks, including the rare occurrence of late-onset donor site morbidities such as compartment syndrome. We report the case of a 67-year-old male with multiple comorbidities who developed compartment syndrome due to delayed hematoma formation at the donor site after undergoing segmental mandibulectomy with left fibular osteocutaneous free flap reconstruction.

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Background Family presence during resuscitation (FPDR) has been a long-debated topic in medical circles in the last 40 years. Studies usually concentrate on the opinions and responses of the family members of the patients being resuscitated. Only a handful of studies have focussed on the medical practitioner's opinions and beliefs on the topic.

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Coronary arteries normally originate from two separate cusps from the aorta, and various anomalies can occur. One such anomaly is the single coronary artery (SCA), where the coronary arteries originate from a single ostium due to the absence of the contralateral ostia. In a rare case we encountered while evaluating a patient with atypical chest pain, computed tomography angiography revealed that the right ostia was absent, and the right coronary artery originated from the left circumflex artery.

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In staging for testicular germ cell tumor (GCT), current guidelines lack consensus regarding the measurement of retroperitoneal lymph node metastasis, concerning the recommended plane and dimension. This exploratory study aimed to assess its impact on clinical stage (cS) and therapy. We retrospectively examined 154 cSI (retroperitoneal lymph nodes < 10 mm in axial short-axis diameter (SAD)) GCT patients, without adjuvant therapy and a follow-up ≥ 24 months.

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Metabolic syndrome (MetS) is a worldwide public health challenge. Accumulating evidence implicates elevated serum ferritin and disruptions in iron metabolism as potential elements linked to an increased risk of MetS. This study investigates the relationship between iron homeostasis-including hepcidin levels, serum iron concentration, unsaturated iron-binding capacity (UIBC), and the hepcidin/ferritin (H/F) ratio-and MetS.

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This systematic review evaluates the efficacy and safety of semaglutide in individuals with obesity or overweight without diabetes. Obesity is a significant public health concern, associated with various comorbidities and reduced quality of life. Semaglutide, a glucagon-like peptide-1 receptor agonist, has emerged as a promising pharmacological intervention for weight management.

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Chronic rhinosinusitis with nasal polyposis (CRSwNP) occurs due to the inflammation of sinonasal tissue. Cases of CRSwNP more commonly demand revision endoscopic sinus surgery (ESS) as compared to patients without polyposis. The recurrence rate varies widely depending on various factors, such as the extent of surgery, patient compliance with postoperative care, and the severity of the underlying disease.

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Hepatocellular carcinoma (HCC) is a common critical type of hepatic cancer worldwide. Recent guidelines have considered ablative therapeutic approaches as the primary option for managing early-stage surgically untreatable HCC. Among these therapies, radiofrequency ablation (RFA) and microwave ablation (MWA) have attained a significant role due to their efficacy and theoretical advantages.

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Introduction: This study aims to develop co-amorphous Solid Dispersion (SD) system containing antimalarials Artesunate (ARS) and Amodiaquine (AMQ) to improve its oral bioavailability employing the Hot Melt Extrusion (HME) technique. Soluplus was selected as a polymeric excipient, whereas Lutrol F127, Lutrol F68, TPGS, and PEG400 as surfactants were incorporated along with Soluplus to enhance extrudability, improve hydrophilicity, and improve the blend viscosity during HME. Soluplus with surfactant combination successfully stabilizes both drugs during extrusion by generating SD because of its lower glass transition temperature (Tg) and viscoelastic behavior.

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  • * A review of five studies indicated corticosteroids significantly reduced pain at 24 hours, with some evidence of decreased antibiotic use, but results showed high variability among studies.
  • * While corticosteroids may help lessen pain intensity and duration, the overall evidence is inconclusive due to study limitations, highlighting the need for better-quality randomized controlled trials (RCTs).
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Background: Though virtual care was widely adopted during the COVID-19 pandemic, evidence to support its use in kidney transplant recipients early after transplantation is limited.

Methods: We conducted a retrospective cohort study comparing post kidney transplant outcomes in patients who received in-person transplant care before the COVID-19 pandemic with those who received mainly virtual transplant care during the COVID-19 pandemic. The usual-care group included 69 patients who received a kidney transplant from March 1, 2019 to September 1, 2019, and the virtual-care group included 64 patients who received a kidney transplant from September 1, 2020 to March 1, 2021.

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Laparoscopic sleeve gastrectomy (LSG) is a popular bariatric procedure with significant effects on weight and metabolic health. However, its impact on gastroesophageal reflux disease (GERD) and esophageal symptoms remains debated. This study aims to evaluate the endoscopic changes five years post-LSG.

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  • European laparoscopic urological skills (LUSs2) curriculum is being developed to fill the gap in intermediate and advanced training for laparoscopic surgical procedures in urology, promoting uniformity and proficiency among practitioners.
  • A Delphi survey with international experts helped create this curriculum; it achieved consensus on 85% of the evaluated statements regarding crucial laparoscopic procedures.
  • The new curriculum aims to enhance surgical education standards, improve surgical skills, and ultimately provide better patient care, although some limitations and potential biases in the process were noted.
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Peripheral nerve sheath tumors (PNSTs), while uncommon, can have a significant impact on appearance and quality of life, especially when they form in prominent areas such as the nose dorsum. We discuss a case of a 29-year-old woman who developed a benign PNST on the right side of her nasal ala. This tumor gradually grew, impairing her face appearance.

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