Select terpenes from Cannabis sativa are antinociceptive in mouse models of post-operative pain and fibromyalgia via adenosine A receptors.

Background: Terpenes from Cannabis show promise for pain management. Our lab found that the terpenes geraniol, linalool, β-caryophyllene, and α-humulene relieve chemotherapy-induced peripheral neuropathy via Adenosine A receptors (AR). This suggests terpenes as potential non-opioid, non-cannabinoid therapeutics.

Association between precipitation events, drought, and animal operations with infections in the Southwest US, 2009-2021.

Background: Temperature and precipitation have previously been associated with infections. The association between salmonellosis and precipitation might be explained by antecedent drought conditions; however, few studies have explored this effect.

Methods: Using an ecological study design with public health surveillance, meteorological (total precipitation [inches], temperature [average °F], Palmer Drought Severity Index [PDSI, category]), and livestock data we explored the association between precipitation and infections reported in 127/141 counties from 2009 to 2021 in the Southwest, US and determined how this association was modified by antecedent drought.